ChemicalBook >> CAS DataBase List >>2-Chloro-6-(trifluoromethyl)pyridine

2-Chloro-6-(trifluoromethyl)pyridine

2-Chloro-6-(trifluoromethyl)pyridine structure

CAS No.: 39890-95-4

Chemical Name:: 2-Chloro-6-(trifluoromethyl)pyridine

Synonyms: FINE ORGANIC COMPOUND;oro-6-(trifL;PYRIDINE DERIVAT;BUTTPARK 27\08-82;Chloro-6-(trifluoroMethyl)pyr;2-Chloro-5-trifluoromethylpyri;2-CHLORO-6-TRIFLUOROMETHYLPRIDINE;6-Chloro-2-(trifluoromethyl)pyridine;2-CHLORO-6-(TRIFLUOROMETHYL)PYRIDINE;PYRIDINE, 2-CHLORO-6-(TRIFLUOROMETHYL)-

CBNumber:: CB2241526

Molecular Formula:: C6H3ClF3N

Molecular Weight:: 181.54

MDL Number:: MFCD00042226

MOL File:: 39890-95-4.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:46

Request For Quotation

2-Chloro-6-(trifluoromethyl)pyridine Properties

Melting point	33 °C
Boiling point	60-62°C 8mm
Density	1.416±0.06 g/cm3(Predicted)
Flash point	78°C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Water Solubility	Insoluble in water
form	powder to lump
pka	-4.30±0.10(Predicted)
color	White to Almost white
FreezingPoint	32.0 to 34.0 ℃
BRN	4308910
InChI	InChI=1S/C6H3ClF3N/c7-5-3-1-2-4(11-5)6(8,9)10/h1-3H
InChIKey	ADVQMCQMDHBTHJ-UHFFFAOYSA-N
SMILES	C1(Cl)=NC(C(F)(F)F)=CC=C1
CAS DataBase Reference	39890-95-4(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

Hazard statements

H300-H319

Precautionary statements

P264-P270-P280-P301+P310-P305+P351+P338-P337+P313

Hazard Codes

T;Xn,Xi,Xn,T

Risk Statements

25-20/21/22-36/37/38-36

Safety Statements

26-36/37/39-45-36/37-9-36

RIDADR

2811

WGK Germany

Hazard Note

Irritant

HazardClass

6.1

PackingGroup

III

HS Code

29333990

NFPA 704

	2
2		0

2-Chloro-6-(trifluoromethyl)pyridine price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	684724	2-Chloro-6-(trifluoromethyl)pyridine 96%	39890-95-4	1g	$25	2023-06-20	Buy
TCI Chemical	C1986	2-Chloro-6-(trifluoromethyl)pyridine >98.0%(GC)	39890-95-4	1g	$40	2025-07-31	Buy
TCI Chemical	C1986	2-Chloro-6-(trifluoromethyl)pyridine >98.0%(GC)	39890-95-4	5g	$119	2025-07-31	Buy
TRC	C432960	2-Chloro-6-(trifluoromethyl)pyridine	39890-95-4	1g	$55	2021-12-16	Buy
Matrix Scientific	007184	2-Chloro-6-(trifluoromethyl)pyridine 98%	39890-95-4	100g	$59	2021-12-16	Buy

Product number	Packaging	Price	Buy
684724	1g	$25	Buy
C1986	1g	$40	Buy
C1986	5g	$119	Buy
C432960	1g	$55	Buy
007184	100g	$59	Buy

2-Chloro-6-(trifluoromethyl)pyridine Chemical Properties,Uses,Production

Chemical Properties

Colorless to off-white liquid (or White to off-white crystal)

Uses

2-Chloro-6-(trifluoromethyl)pyridine can be used in the synthesis of medicine, pesticide or biocidal product.

Chemical Reactivity

2-Chloro-6-(trifluoromethyl)pyridine is stable under recommended storage conditions, it reacts with strong oxidizing agents, strong acids, strong bases.

Synthesis

1929-82-4

39890-95-4

General procedure for the synthesis of 2-chloro-6-trichloromethylpyridine from 2-chloro-6-trichloromethylpyridine: 2-chloro-6-trichloromethylpyridine (700 g, 3.03 mol, feed rate 1.24 g/min) and anhydrous hydrogen fluoride (936 g, 46.8 mol, feed rate 1.66 g/min) were added successively to a tubular reactor fitted with a preactivated chromium oxide-alumina catalyst (210 g) in a tubular reactor at a reaction temperature of 330 °C. The reaction products were cooled with ice water and collected. The reaction products were collected after cooling with ice water and extracted with dichloromethane. The extract was washed with 10% potassium hydroxide solution, and the organic layer was separated and concentrated to give 490.0 g of crude 2-chloro-6-trifluoromethylpyridine, which was analyzed by GC for 95.03% purity and 89% reaction yield. The crude product was purified by fractionation to obtain 2-chloro-6-trifluoromethylpyridine with 98.0% purity and 80.0% yield.

References

[1] Patent: WO2016/178248, 2016, A1. Location in patent: Page/Page column 5

2-Chloro-6-(trifluoromethyl)pyridine Preparation Products And Raw materials

Raw materials

2-Amino-6-(trifluoromethyl)pyridine Nitrapyrin

Preparation Products

6-(6-(trifluoromethyl)pyridin-2-yl)-1,3,5-triazine-2,4(1H,3H)-dione 2,6-BIS(TRIFLUOROMETHYL)PYRIDINE 4-[6-(TRIFLUOROMETHYL)PYRIDIN-2-YL]MORPHOLINE 2-HYDRAZINO-6-(TRIFLUOROMETHYL)PYRIDINE

2-Chloro-6-(trifluoromethyl)pyridine Suppliers

Global( 412)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shandong Jihui Chemical Co., Ltd.	+8615053042019	sales@jihuichem.com	China	34	58
Hebei Chuanghai Biotechnology Co., Ltd	+8617732866630	abby@chuanghaibio.com	China	8773	58
Hebei Mujin Biotechnology Co.,Ltd	+8613288715578	sales@hbmojin.com	China	12371	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	615	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29734	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21622	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +8618949832763	info@tnjchem.com	China	2988	55

Supplier	Advantage
Shandong Jihui Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Nantong Guangyuan Chemicl Co,Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Hefei TNJ Chemical Industry Co.,Ltd.	55

View Lastest Price from 2-Chloro-6-(trifluoromethyl)pyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-15	2-Chloro-6-(trifluoromethyl)pyridine 39890-95-4	US $0.00-0.00 / KG	250KG	Purity: 99%	1000tons	Shandong Jihui Chemical Co., Ltd.
2025-08-08	2-Chloro-6-(trifluoromethyl)pyridine 39890-95-4	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mujin Biotechnology Co.,Ltd
2025-08-08	2-Chloro-6-(trifluoromethyl)pyridine 39890-95-4	US $120.00 / KG	1KG	99%	5000KG	Hebei Mujin Biotechnology Co.,Ltd

2-Chloro-6-(trifluoromethyl)pyridine
39890-95-4
US $0.00-0.00 / KG
Purity: 99%
Shandong Jihui Chemical Co., Ltd.

2-Chloro-6-(trifluoromethyl)pyridine
39890-95-4
US $0.00 / KG
99%
Hebei Mujin Biotechnology Co.,Ltd

2-Chloro-6-(trifluoromethyl)pyridine
39890-95-4
US $120.00 / KG
99%
Hebei Mujin Biotechnology Co.,Ltd

2-Chloro-6-(trifluoromethyl)pyridine Spectrum

2-Chloro-6-(trifluoromethyl)pyridine(39890-95-4)MS 2-Chloro-6-(trifluoromethyl)pyridine(39890-95-4)¹HNMR 2-Chloro-6-(trifluoromethyl)pyridine(39890-95-4)¹³CNMR 2-Chloro-6-(trifluoromethyl)pyridine(39890-95-4)IR1 2-Chloro-6-(trifluoromethyl)pyridine(39890-95-4)IR2

39890-95-4(2-Chloro-6-(trifluoromethyl)pyridine)Related Search:

3-Aminobenzotrifluoride 3-(Trifluoromethyl)benzaldehyde 2,4,6-Collidine 2-Chloro-5-chloromethylpyridine 2-(Trifluoromethyl)pyridine

Trifluoromethanesulfonic acid 2,6-Lutidine 2-(Trifluoromethyl)benzyl chloride 2-Chloro-6-methylpyridine 2-Fluoro-6-trifluoromethylpyridine

Azamethiphos 3-Trifluoromethylpyridine Epichlorohydrin 4-Methylpyridine 2-(Trifluoromethyl)benzoic acid

Pyridine Nitrapyrin 4-(Trifluoromethyl)pyridine

1of4

BUTTPARK 27\08-82 PYRIDINE, 2-CHLORO-6-(TRIFLUOROMETHYL)- 2-CHLORO-6-(TRIFLUOROMETHYL)PYRIDINE 6-Chloro-2-(trifluoromethyl)pyridine 2-CHLORO-6-TRIFLUOROMETHYLPRIDINE 2-Chloro-5-trifluoromethylpyri 2-CHLORO-6-TRIFLUOROMETHYL-PYRIDINE >97% oro-6-(trifL 6-Chloro-alpha,alpha,alpha-trifluoro-2-picoline Chloro-6-(trifluoroMethyl)pyr 2-chloro -6-three fluorineMethyl pyridine FINE ORGANIC COMPOUND PYRIDINE DERIVAT 2-Chloro-6-(trifluoromethyl)pyridine> 2-Chloro-6-(trifluoromethyl)pyridine ISO 9001：2015 REACH 2-Chloro-6-(trifluoromethyl)pyridine, ≥ 98.0% 39890-95-4 39890-95-7 30.9890-95-4 1478-14-8 C6H3CIF3N C6F3H3ClN C6H3ClF3N Heterocyclic Building Blocks Halogenated Heterocycles Pyridines Chloropyridines Halopyridines Building Blocks Fluorine series alkyl chloride Chloropyridines Halopyridines C6Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyridine series Pyridines, Pyrimidines, Purines and Pteredines Pyridines Pyridine Pyridines derivates Halides Heterocycles