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ChemicalBook >> CAS DataBase List >>(1E)-1-Cyanomethylene-2-cyclohexene-4α,6α-diol

(1E)-1-Cyanomethylene-2-cyclohexene-4α,6α-diol

(1E)-1-Cyanomethylene-2-cyclohexene-4α,6α-diol Structure
(1E)-1-Cyanomethylene-2-cyclohexene-4α,6α-diol structure
CAS No.
127350-68-9
Chemical Name:
(1E)-1-Cyanomethylene-2-cyclohexene-4α,6α-diol
Synonyms
Coclauril;(1E)-1-Cyanomethylene-2-cyclohexene-4α,6α-diol;Acetonitrile, [(4R,6S)-4,6-dihydroxy-2-cyclohexen-1-ylidene]-, (2E)- (9CI)
CBNumber:
CB22429564
Molecular Formula:
C8H9NO2
Molecular Weight:
151.16
MDL Number:
MFCD20260939
MOL File:
127350-68-9.mol
Last updated:2025-04-18 09:51:50
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(1E)-1-Cyanomethylene-2-cyclohexene-4α,6α-diol Properties

Melting point 121-124 °C
Boiling point 392.0±42.0 °C(Predicted)
Density 1.449±0.06 g/cm3(Predicted)
pka 13.03±0.40(Predicted)

(1E)-1-Cyanomethylene-2-cyclohexene-4α,6α-diol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Arctom CFN99383 Coclauril ≥98% 127350-68-9 5mg $553 2021-12-16 Buy
Crysdot CD32002616 Coclauril 95+% 127350-68-9 5mg $852 2021-12-16 Buy
Product number Packaging Price Buy
CFN99383 5mg $553 Buy
CD32002616 5mg $852 Buy

(1E)-1-Cyanomethylene-2-cyclohexene-4α,6α-diol Chemical Properties,Uses,Production

Uses

Coclauril is an inhibitor of HBV. Coclauril inhibits HBV replication in the human hepatoblastoma cell line with an EC50 of 7.6 μg/mL[1].

References

[1] Yi XX, et al. Four New Cyclohexylideneacetonitrile Derivatives from the Hypocotyl of Mangrove (Bruguiera gymnorrhiza). Molecules. 2015 Aug 12;20(8):14565-75. DOI:10.3390/molecules200814565
[2] YOGO Motoi, et al. Coclauril, a nonglucosidic 2-cyclohexen-1-ylideneacetonitrile, from Cocculus lauriforius DC.. CHEMICAL & PHARMACEUTICAL BULLETIN, 38(1), 225–226.

(1E)-1-Cyanomethylene-2-cyclohexene-4α,6α-diol Preparation Products And Raw materials

Raw materials

Preparation Products

(1E)-1-Cyanomethylene-2-cyclohexene-4α,6α-diol Suppliers

Global( 34)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		support@targetmol.com United States 38663 58
Chembest Research Laboratories Limited +86-21-20908456 sales@BioChemBest.com China 6005 61
BioBioPha Co., Ltd. 0871-65217109 13211707573; y.liu@mail.biobiopha.com China 5653 65
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632 sales@reading-chemicals.com China 15178 58
ALB Technology Limited 702-983-3769 sales@albtechnology.com United States 2993 55
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6905 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60
Shanghai Hongshun Biological Technology Co., Ltd. 15901914505 15901914505 3187892335@qq.com China 10793 58
Absin Bioscience Inc. 021-38015121 18438616290 wulan@absin.cn China 24731 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Chembest Research Laboratories Limited 61
BioBioPha Co., Ltd. 65
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58
ALB Technology Limited 55
Wuhan ChemFaces Biochemical Co., Ltd. 55
EMMX Biotechnology LLC 60
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Hongshun Biological Technology Co., Ltd. 58
Absin Bioscience Inc. 58
(1E)-1-Cyanomethylene-2-cyclohexene-4α,6α-diol Coclauril Acetonitrile, [(4R,6S)-4,6-dihydroxy-2-cyclohexen-1-ylidene]-, (2E)- (9CI) 127350-68-9