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1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE

CAS No.
351457-12-0
Chemical Name:
1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE
Synonyms
1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMID;1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE;N-Methoxy-N-Methyl-1H-indazole-3-carboxaMide;1H-Indazole-3-carboxamide, N-methoxy-N-methyl-
CBNumber:
CB22464945
Molecular Formula:
C10H11N3O2
Molecular Weight:
205.21
MDL Number:
MFCD11809319
MOL File:
351457-12-0.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:45
Product description Number Pack Size Price
N-Methoxy-N-methyl-1H-indazole-3-carboxamide 96% AA007FID 1g $24
N-Methoxy-N-methyl-1H-indazole-3-carboxamide 96% AA007FID 5g $57
N-Methoxy-N-methyl-1H-indazole-3-carboxamide 96% AA007FID 10g $92
N-Methoxy-N-methyl-1H-indazole-3-carboxamide 96% AA007FID 25g $218
N-Methoxy-N-methyl-1H-indazole-3-carboxamide 95% CD11137929 25g $320

1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE Properties

storage temp. Store at room temperature
Appearance White to yellow Solid

1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA007FID N-Methoxy-N-methyl-1H-indazole-3-carboxamide 96% 351457-12-0 1g $24 2026-05-28 Buy
aablocks AA007FID N-Methoxy-N-methyl-1H-indazole-3-carboxamide 96% 351457-12-0 5g $57 2026-05-28 Buy
aablocks AA007FID N-Methoxy-N-methyl-1H-indazole-3-carboxamide 96% 351457-12-0 10g $92 2026-05-28 Buy
aablocks AA007FID N-Methoxy-N-methyl-1H-indazole-3-carboxamide 96% 351457-12-0 25g $218 2026-05-28 Buy
Crysdot CD11137929 N-Methoxy-N-methyl-1H-indazole-3-carboxamide 95% 351457-12-0 25g $320 2026-05-26 Buy
Product number Packaging Price Buy
AA007FID 1g $24 Buy
AA007FID 5g $57 Buy
AA007FID 10g $92 Buy
AA007FID 25g $218 Buy
CD11137929 25g $320 Buy

1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE Chemical Properties,Uses,Production

Synthesis

N,O-Dimethylhydroxylamine hydrochloride

6638-79-5

Indazole-3-carboxylic acid

4498-67-3

1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE

351457-12-0

Indazole-3-carboxylic acid (10 g, 61.7 mmol) was used as a raw material, which was dissolved in DMF (100 mL), and carbonyldiimidazole (11 g, 67.84 mmol) was slowly added at room temperature, and gas was observed to be released during the reaction for 15 min. Subsequently, the reaction mixture was heated to 65 °C and maintained for 2 hours. After completion of the reaction, the mixture was cooled to room temperature, N,O-dimethylhydroxylamine hydrochloride (4.14 g, 67.8 mmol) was added and the mixture was again heated to 65 °C and reacted overnight. At the end of the reaction, the reaction mixture was cooled, the reaction was quenched with water, extracted with dichloromethane (CH2Cl2) and the organic phase was washed with water. The organic phases were combined and concentrated after drying to afford the target product N-methoxy-N-methyl-1H-indazole-3-carboxamide (10.3 g, 81.4% yield).

References

[1] Tetrahedron Letters, 2007, vol. 48, # 14, p. 2457 - 2460
[2] Tetrahedron, 2007, vol. 63, # 2, p. 419 - 428
[3] Patent: WO2008/71451, 2008, A1. Location in patent: Page/Page column 50
[4] Patent: WO2013/40215, 2013, A1. Location in patent: Paragraph 00334
[5] Patent: US2013/267495, 2013, A1. Location in patent: Paragraph 0409

6638-79-5
4498-67-3
351457-12-0
Synthesis of 1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE from N,O-Dimethylhydroxylamine hydrochloride and Indazole-3-carboxylic acid

1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE Suppliers

Global( 57)Suppliers
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Alchem Pharmtech,Inc.
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Career Henan Chemica Co
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Amadis Chemical Company Limited
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Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60

1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE Spectrum

1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE 1H-Indazole-3-carboxamide, N-methoxy-N-methyl- N-Methoxy-N-Methyl-1H-indazole-3-carboxaMide 1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMID 351457-12-0