ethyl 1-acetylcyclopropanecarboxylate
- CAS No.
- 32933-03-2
- Chemical Name:
- ethyl 1-acetylcyclopropanecarboxylate
- Synonyms
- thyl 1-acetylcyclopropanecarboxylate;ethyl 1-acetylcyclopropanecarboxylate;Ethyl 1-acetylcyclopropane-1-carboxylate;1-Acetylcyclopropancarbonsaeure-ethylester;1-Acetyl-cyclopropanecarboxylic acid ethyl ester;1-acetyl-1-cyclopropanecarboxylic acid ethyl ester;Cyclopropanecarboxylic acid, 1-acetyl-, ethyl ester;1-acetyl-Cyclopropanecarboxylic acid ethyl ester (8CI 9CI ACI);Cyclopropanecarboxylic acid, 1-acetyl-, ethyl ester (8CI, 9CI, ACI)
- CBNumber:
- CB22499747
- Molecular Formula:
- C8H12O3
- Molecular Weight:
- 156.18
- MDL Number:
- MFCD00480999
- MOL File:
- 32933-03-2.mol
| Product description | Number | Pack Size | Price |
| (3-Oxocyclohexyl)acetic acid AldrichCPR | PH018197 | 1G | $201 |
| Ethyl 1-Acetylcyclopropane-1-carboxylate min. 98.0 % | E1442 | 1G | $94 |
| Ethyl 1-Acetylcyclopropane-1-carboxylate min. 98.0 % | E1442 | 5G | $284 |
| Ethyl1-acetylcyclopropanecarboxylate | E896430 | 100mg | $65 |
| Ethyl 1-acetylcyclopropane-1-carboxylate >95% | 077028 | 500mg | $74 |
| More product size | |||
| Boiling point | 42-44 °C(Press: 2 Torr) |
|---|---|
| Density | 1.139±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | solid |
| Appearance | Colorless to light yellow Liquid |
| InChI | InChI=1S/C8H12O3/c1-3-11-7(10)8(4-5-8)6(2)9/h3-5H2,1-2H3 |
| InChIKey | DISZFIFAESWGBI-UHFFFAOYSA-N |
| SMILES | C1(C(C)=O)(C(OCC)=O)CC1 |
| UNSPSC Code | 12352106 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 |
| HS Code | 2902190000 |
ethyl 1-acetylcyclopropanecarboxylate price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PH018197 | (3-Oxocyclohexyl)acetic acid AldrichCPR | 32933-03-2 | 1G | $201 | 2023-06-20 | Buy |
| TCI Chemical | E1442 | Ethyl 1-Acetylcyclopropane-1-carboxylate min. 98.0 % | 32933-03-2 | 1G | $94 | 2025-07-31 | Buy |
| TCI Chemical | E1442 | Ethyl 1-Acetylcyclopropane-1-carboxylate min. 98.0 % | 32933-03-2 | 5G | $284 | 2025-07-31 | Buy |
| TRC | E896430 | Ethyl1-acetylcyclopropanecarboxylate | 32933-03-2 | 100mg | $65 | 2021-12-16 | Buy |
| Matrix Scientific | 077028 | Ethyl 1-acetylcyclopropane-1-carboxylate >95% | 32933-03-2 | 500mg | $74 | 2021-12-16 | Buy |
ethyl 1-acetylcyclopropanecarboxylate Chemical Properties,Uses,Production
Uses
ethyl 1-methyl cyclopropanecarboxylate is an important pharmaceutical intermediate used in the addition of cyclopropane.
Synthesis
141-97-9
106-93-4
32933-03-2
Step 1) Synthesis of ethyl 1-acetylcyclopropanecarboxylate: To a solution of ethyl 3-oxobutanoate (26 g, 200 mmol) in acetone (500 mL) was added potassium carbonate (82.8 g, 600 mmol) followed by 1,2-dibromoethane (45.12 g, 240 mmol). The reaction mixture was refluxed for 24 hours. After completion of the reaction, the mixture was filtered and the filtrate was concentrated under vacuum. The residue was purified by silica gel column chromatography with an eluent ratio of 1:50 (v/v) ethyl acetate/hexane to afford the target compound ethyl 1-acetylcyclopropanecarboxylate as a colorless oil (18.7 g, 60% yield). Mass spectrum (ESI, cation mode) m/z: 157 (M+1); 1H NMR (400 MHz, CDCl3) δ: 1.25-1.29 (t, J=7.2 Hz, 3H), 1.45 (s, 4H), 2.45 (s, 3H), 4.18-4.20 (q, 2H).
References
[1] Tetrahedron Letters, 2005, vol. 46, # 4, p. 635 - 638
[2] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004, vol. 43, # 2, p. 420 - 422
[3] Tetrahedron Asymmetry, 2010, vol. 21, # 5, p. 631 - 635
[4] Journal of Organic Chemistry, 2011, vol. 76, # 8, p. 2807 - 2813
[5] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983, vol. 19, # 6, p. 644 - 650
ethyl 1-acetylcyclopropanecarboxylate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Yushan Wanfang Biotechnology Co., Ltd. | +86-025-84918180 +86-18014482516 | 3552541679@qq.com | China | 997 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 4000 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29799 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9629 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
View Lastest Price from ethyl 1-acetylcyclopropanecarboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-05-12 | ethyl 1-acetylcyclopropanecarboxylate
32933-03-2
|
US $0.00 / kg | 1kg | 98% | 2 MTs | PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD | |
 |
2024-08-13 | ethyl 1-acetylcyclopropanecarboxylate
32933-03-2
|
US $1.00 / KG | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-01-09 | ethyl 1-acetylcyclopropanecarboxylate
32933-03-2
|
US $6.68 / KG | 1KG | 97%-99% | 1kg-1000kg | Career Henan Chemical Co |
-
- ethyl 1-acetylcyclopropanecarboxylate
32933-03-2
- US $0.00 / kg
- 98%
- PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
-
- ethyl 1-acetylcyclopropanecarboxylate
32933-03-2
- US $1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- ethyl 1-acetylcyclopropanecarboxylate
32933-03-2
- US $6.68 / KG
- 97%-99%
- Career Henan Chemical Co
