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5-Chloro-4-(trifluoromethyl)pyridin-2-amine

5-Chloro-4-(trifluoromethyl)pyridin-2-amine Structure
5-Chloro-4-(trifluoromethyl)pyridin-2-amine structure
CAS No.
1095823-39-4
Chemical Name:
5-Chloro-4-(trifluoromethyl)pyridin-2-amine
Synonyms
5-Chloro-4-(trifluoromethyl);5-Chloro-4-(trifluoromethyl)-2-pyridinamine;5-Chloro-4-(trifluoromethyl)pyridin-2-amine;5-chloro-4-(trifluoromethyl)pyridin-3-amine;5-Chloro-4-trifluoromethyl-pyridin-2-ylamine;2-PyridinaMine, 5-chloro-4-(trifluoroMethyl)-;305-Chloro-4-(triFluoroMethyl)Pyridine-2-amine;2- amino -4- three fluoromethyl -5- chlorpyridine
CBNumber:
CB22504805
Molecular Formula:
C6H4ClF3N2
Molecular Weight:
196.56
MDL Number:
MFCD18255015
MOL File:
1095823-39-4.mol
MSDS File:
SDS
Last updated:2026-05-28 00:01:15
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5-Chloro-4-(trifluoromethyl)pyridin-2-amine Properties

Boiling point 258.3±40.0 °C(Predicted)
Density 1.507±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form powder
pka 2.47±0.24(Predicted)
color Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P260-P280-P312
HS Code  2933399990

5-Chloro-4-(trifluoromethyl)pyridin-2-amine price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC01524 2-Amino-5-chloro-4-(trifluoromethyl)pyridine ≥95% 1095823-39-4 250mg $32 2026-06-04 Buy
Apolloscientific PC01524 2-Amino-5-chloro-4-(trifluoromethyl)pyridine ≥95% 1095823-39-4 1g $56 2026-06-04 Buy
Apolloscientific PC01524 2-Amino-5-chloro-4-(trifluoromethyl)pyridine ≥95% 1095823-39-4 5g $277 2026-06-04 Buy
Activate Scientific AS28439 2-Amino-5-chloro-4-(trifluoromethyl)pyridine 97% 1095823-39-4 1g $88 2026-06-04 Buy
Activate Scientific AS28439 2-Amino-5-chloro-4-(trifluoromethyl)pyridine 97% 1095823-39-4 5g $215 2026-06-04 Buy
Product number Packaging Price Buy
PC01524 250mg $32 Buy
PC01524 1g $56 Buy
PC01524 5g $277 Buy
AS28439 1g $88 Buy
AS28439 5g $215 Buy

5-Chloro-4-(trifluoromethyl)pyridin-2-amine Chemical Properties, Uses, Production

Synthesis

2-Amino-4-(trifluoromethyl)pyridine

106447-97-6

5-Chloro-4-(trifluoromethyl)pyridin-2-amine

1095823-39-4

Synthesis of Compound A.6: To a solution of 2-amino-4-trifluoromethylpyridine (2.00 g, 12.3 mmol) in N,N-dimethylformamide (DMF, 4 mL) was slowly added a solution of 1,3-dichloro-5,5-dimethylglycolide (1.4 g, 7.4 mmol) in DMF (4 mL). The reaction mixture was stirred at room temperature for 2 hours. After completion of the reaction, the mixture was diluted with ether (80 mL) and washed with deionized water (10 mL). The organic phase was separated, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by fast column chromatography (eluent: 0-20% ethyl acetate/hexane) to afford compound A.6 as a light yellow oil in 65% yield.1H NMR (DMSO-d6) δ: 8.16 (s, 1H), 6.87 (s, 1H), 6.76 (br s, 1H); MS: m/z 197 [M + H]+.

References

[1] Patent: US2009/5359, 2009, A1. Location in patent: Page/Page column 33
[2] Patent: US2009/36419, 2009, A1. Location in patent: Page/Page column 78
[3] Patent: WO2010/78408, 2010, A1. Location in patent: Page/Page column 86; 87; 88

5-Chloro-4-(trifluoromethyl)pyridin-2-amine Preparation Products And Raw materials

Raw materials

2-Amino-4-(trifluoromethyl)pyridine 1,3-Dichloro-5,5-dimethylhydantoin N,N-Dimethylformamide

Preparation Products

5-Chloro-4-(trifluoromethyl)pyridin-2-amine Suppliers

Global Suppliers ( 97)
Supplier Tel Email Country ProdList Advantage
Jinan Kabotang Biological Technology Co.,Ltd. 0531-61320525 15866703830 figo.gao@foxmail.com China 7601 58
Changzhou Huanling Chemical Co., Ltd. 89803005 18206112582 info@huanlingchem.com China 983 68
China Langchem Inc. 0086-21-58956006 China 7798 57
Nanjing JinruiJiuAn Biotechnology Co., Ltd. 025-58196018 800028039 sales@fartop.net China 2227 55
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7545 61
Shanghai Keepontech Co.,Ltd 021-54849683 13601642561 sales@keepontech.com China 998 59
SuZhou ShiYa Biopharmaceuticals, Inc. 86(512)5235 8471 17715136450 sales@shiyabiopharm.com China 4167 58
SynAsst Chemical. 021-60343070 China 12731 55
Yancheng Orgunion Pharmaceutical Sci & Tech Co., Ltd. 0515-89701588 13770166955 orgunion@orgunion.com China 620 55
Cochemical Ltd. 029-86115547 17791676824 sales@cochemical.com China 3014 58
Supplier Advantage
Jinan Kabotang Biological Technology Co.,Ltd. 58
Changzhou Huanling Chemical Co., Ltd. 68
China Langchem Inc. 57
Nanjing JinruiJiuAn Biotechnology Co., Ltd. 55
Haoyuan Chemexpress Co., Ltd. 61
Shanghai Keepontech Co.,Ltd 59
SuZhou ShiYa Biopharmaceuticals, Inc. 58
SynAsst Chemical. 55
Yancheng Orgunion Pharmaceutical Sci & Tech Co., Ltd. 55
Cochemical Ltd. 58

View Latest Price from 5-Chloro-4-(trifluoromethyl)pyridin-2-amine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Chloro-4-(trifluoromethyl)pyridin-2-amine pictures 2022-01-15 5-Chloro-4-(trifluoromethyl)pyridin-2-amine
1095823-39-4
 1KG 98.0% 100 tons Honest Joy Holdings Limited
5-Chloro-4-(trifluoromethyl)pyridin-2-amine pictures 2019-12-26 5-Chloro-4-(trifluoromethyl)pyridin-2-amine
1095823-39-4
 $1.00 1KG 99% 1000KGS Career Henan Chemical Co

5-Chloro-4-(trifluoromethyl)pyridin-2-amine Spectrum

5-Chloro-4-(trifluoromethyl)pyridin-2-amine(1095823-39-4)1HNMR

1095823-39-4 (5-Chloro-4-(trifluoromethyl)pyridin-2-amine) Related Search:

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5-chloro-4-(difluoromethyl)pyridin-2-amine

1of2

5-Chloro-4-(trifluoromethyl)pyridin-2-amine 2-PyridinaMine, 5-chloro-4-(trifluoroMethyl)- 5-Chloro-4-trifluoromethyl-pyridin-2-ylamine 5-chloro-4-(trifluoromethyl)pyridin-3-amine 5-Chloro-4-(trifluoromethyl) 2- amino -4- three fluoromethyl -5- chlorpyridine 5-Chloro-4-(trifluoromethyl)-2-pyridinamine 305-Chloro-4-(triFluoroMethyl)Pyridine-2-amine 1095823-39-4