5-Bromo-4-fluoro-2-hydroxy-benzaldehyde
- CAS No.
- 399-00-8
- Chemical Name:
- 5-Bromo-4-fluoro-2-hydroxy-benzaldehyde
- Synonyms
- 5-Bromo-4-fluorosalicylaldehyde;4-Fluoro-5-bromo-2-hydroxybenzaldehyde;5-Bromo-4-fluoro-2-hydroxy-benzaldehyde;Benzaldehyde, 5-bromo-4-fluoro-2-hydroxy-;5-Bromo-4-fluoro-2-hydroxybenzaldehyde 98%
- CBNumber:
- CB2250799
- Molecular Formula:
- C7H4BrFO2
- Molecular Weight:
- 219.01
- MDL Number:
- MFCD06739493
- MOL File:
- Mol file
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2913000090 |
5-Bromo-4-fluoro-2-hydroxy-benzaldehyde price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC430579 | 5-Bromo-4-fluoro-2-hydroxybenzaldehyde >97% | 399-00-8 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC430579 | 5-Bromo-4-fluoro-2-hydroxybenzaldehyde >97% | 399-00-8 | 1g | $45 | 2026-06-04 | Buy |
| Apolloscientific | PC430579 | 5-Bromo-4-fluoro-2-hydroxybenzaldehyde >97% | 399-00-8 | 5g | $214 | 2026-06-04 | Buy |
| Apolloscientific | PC430579 | 5-Bromo-4-fluoro-2-hydroxybenzaldehyde >97% | 399-00-8 | 25g | $997 | 2026-06-04 | Buy |
| Apolloscientific | PC430579 | 5-Bromo-4-fluoro-2-hydroxybenzaldehyde >97% | 399-00-8 | 100g | $3556 | 2026-06-04 | Buy |
5-Bromo-4-fluoro-2-hydroxy-benzaldehyde Chemical Properties, Uses, Production
Synthesis
348-28-7
399-00-8
The general procedure for the synthesis of 5-bromo-4-fluoro-2-hydroxybenzaldehyde using 4-fluoro-2-hydroxybenzaldehyde as starting material was as follows: a solution of bromine (14.1 g, 88.3 mmol) dissolved in chloroform (25 mL) was added slowly and dropwise over a period of 10 min to a solution of chloroform (68 mL) containing 4-fluoro-2-hydroxybenzaldehyde (13.6 g, 97.1 mmol) in a round bottomed flask. The reaction mixture was stirred at room temperature for 16 hours and then the same amount of bromine (14.1 g) was added. Stirring was continued at room temperature for 24 hours. Upon completion of the reaction, the mixture was washed twice with 30% aqueous sodium thiosulfate to remove the color, followed by washing with water and drying the organic layer with anhydrous sodium sulfate. Finally, the organic phase was concentrated by decompression to afford the target product 5-bromo-4-fluoro-2-hydroxybenzaldehyde (21.3 g, 100% yield).
References
[1] Patent: WO2012/40641, 2012, A2. Location in patent: Page/Page column 135; 136
[2] Journal of Medicinal Chemistry, 2004, vol. 47, # 12, p. 3163 - 3179
[3] Patent: US6642222, 2003, B2
[4] Patent: US6593335, 2003, B1
[5] Patent: WO2013/91096, 2013, A1. Location in patent: Page/Page column 37
5-Bromo-4-fluoro-2-hydroxy-benzaldehyde Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Xi'an NewProChem Co.,Ltd. | 15332490153 | newprochem@126.com | China | 991 | 55 |
| Changzhou Anxuan Chemical, Co., Ltd. | 13912302692 | sales@anxuanchem.com | China | 4824 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shanghai CR Corporation Limited | 13917420128 13062833949 | fred.wen@crcorporation.cn | China | 9769 | 58 |
View Latest Price from 5-Bromo-4-fluoro-2-hydroxy-benzaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE
399-00-8
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2024-04-28 | 5-Bromo-4-fluoro-2-hydroxybenzaldehyde
399-00-8
|
$5.00 | 1kg | 99.92% | 50000tons | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2024-04-24 | 5-Bromo-4-Fluoro-2-Hydroxy-Benzaldehyde
399-00-8
|
$30.00-100.00 | 1kg | 99.93% | 1000kg per week | Ouhuang Engineering Materials (Hubei) Co., Ltd |
-
- 5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE
399-00-8
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 5-Bromo-4-fluoro-2-hydroxybenzaldehyde
399-00-8
- $5.00
- 99.92%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
-
- 5-Bromo-4-Fluoro-2-Hydroxy-Benzaldehyde
399-00-8
- $30.00-100.00
- 99.93%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
