Methyl 4-amino-5-iodo-2-methylbenzoate
- CAS No.
- 672293-33-3
- Chemical Name:
- Methyl 4-amino-5-iodo-2-methylbenzoate
- Synonyms
- 187484;Methyl 4-amino-5-iodo-2-methylbenzoate;4-Amino-5-iodo-2-methyl-benzoic acid methyl ester;Benzoic acid, 4-amino-5-iodo-2-methyl-, methyl ester
- CBNumber:
- CB22534945
- Molecular Formula:
- C9H10INO2
- Molecular Weight:
- 291.09
- MDL Number:
- MFCD11112906
- MOL File:
- 672293-33-3.mol
- MSDS File:
- SDS
Methyl 4-amino-5-iodo-2-methylbenzoate price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | XBB29333 | Methyl 4-amino-5-iodo-2-methylbenzoate | 672293-33-3 | 2.5g | $531 | 2026-06-05 | Buy |
| Matrix Scientific | 306698 | Methyl 4-amino-5-iodo-2-methylbenzoate | 672293-33-3 | 1.00g | $115 | 2026-05-19 | Buy |
| Matrix Scientific | 306698 | Methyl 4-amino-5-iodo-2-methylbenzoate | 672293-33-3 | 5.00g | $500 | 2026-05-19 | Buy |
| Matrix Scientific | 306698 | Methyl 4-amino-5-iodo-2-methylbenzoate | 672293-33-3 | 10.00g | $935 | 2026-05-19 | Buy |
| Synthonix | M49843 | Methyl 4-amino-5-iodo-2-methylbenzoate 97% | 672293-33-3 | 100mg | $28 | 2026-05-06 | Buy |
Methyl 4-amino-5-iodo-2-methylbenzoate Chemical Properties, Uses, Production
Synthesis
6933-47-7
672293-33-3
Methyl 2-methyl-4-aminobenzoate (Intermediate 7) (2.9 g, 16.6 mmol) was used as raw material and dissolved in DMF (15 ml), sodium periodate (1.45 g, 6.6 mmol) and iodine (3.4 g, 13.3 mmol) were added sequentially. The reaction mixture was stirred at a constant temperature at 50°C for 2 hours. After the reaction was completed, the mixture was slowly poured into cold water containing NaHSO3 (0.5 g). After stirring and mixing, the mixture was allowed to stand overnight. On the following day, the precipitate was collected by filtration, washed with water and subsequently dissolved with dichloromethane. The resulting solution was dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure to afford the target product methyl 4-amino-5-iodo-2-methylbenzoate as an orange solid (4.1 g, 85% yield). The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 8.20 (s, 1H), 6.47 (s, 1H), 3.75 (s, 3H), 2.42 (s, 3H).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 3, p. 942 - 945
[2] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 3, p. 946 - 949
[3] Patent: WO2009/47240, 2009, A1. Location in patent: Page/Page column 30
[4] Patent: US2018/291002, 2018, A1. Location in patent: Paragraph 0462; 0463
[5] Patent: US2004/142940, 2004, A1. Location in patent: Page/Page column 42
Methyl 4-amino-5-iodo-2-methylbenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
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| ShangHai Movin Pharmaceutical Co., Ltd. | 13681854265 | info@moenpharm.com | China | 488 | 55 |
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| Shanghai Zhen Li Biological Technology Co., Ltd | 021-16621358918; 18516310516;16621358918;13045646768 | zhenlipharma888@163.com | China | 19060 | 58 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15078 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49299 | 58 |
| Shanghai Botuo Biotechnology Co., LTD | 16621358918 | botuopharma888@163.com | China | 9192 | 58 |
