1-(2-Amino-1,3-thiazol-5-yl)ethan-1-one
- CAS No.
- 53159-71-0
- Chemical Name:
- 1-(2-Amino-1,3-thiazol-5-yl)ethan-1-one
- Synonyms
- 2-Amino-5-acetylthiazole;1-(2-Aminothiazol-5-yl)ethan-1-one;5-Acetyl-2-aminothiazole;5-Acetyl-2-amino-1,3-thiazole;1-(2-AMinothiazol-5-yl)ethanone;Ethanone, 1-(2-amino-5-thiazolyl)-;1-(2-Amino-1,3-thiazol-5-yl)ethanone;1-(2-Amino-1,3-thiazol-5-yl)ethan-1-one;1-(2-Amino-1,3-thiazol-5-yl)ethan-1-one, 2-Amino-5-ethanoyl-1,3-thiazole
- CBNumber:
- CB22559845
- Molecular Formula:
- C5H6N2OS
- Molecular Weight:
- 142.18
- MDL Number:
- MFCD00775044
- MOL File:
- 53159-71-0.mol
- MSDS File:
- SDS
| Melting point | 176-178 °C |
|---|---|
| Boiling point | 303.1±15.0 °C(Predicted) |
| Density | 1.341±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 2.88±0.10(Predicted) |
| Appearance | Yellow to brown Solid |
| InChI | InChI=1S/C5H6N2OS/c1-3(8)4-2-7-5(6)9-4/h2H,1H3,(H2,6,7) |
| InChIKey | XJKIEXPVXXFORX-UHFFFAOYSA-N |
| SMILES | C(=O)(C1SC(N)=NC=1)C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| HS Code | 2934100090 |
1-(2-Amino-1,3-thiazol-5-yl)ethan-1-one price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 50879 | 1-(2-AMINOTHIAZOL-5-YL)ETHANONE 97% | 53159-71-0 | 0.25G | $29 | 2026-04-30 | Buy |
| AstaTech | 50879 | 1-(2-AMINOTHIAZOL-5-YL)ETHANONE 97% | 53159-71-0 | 1G | $54 | 2026-04-30 | Buy |
| AstaTech | 50879 | 1-(2-AMINOTHIAZOL-5-YL)ETHANONE 97% | 53159-71-0 | 5G | $200 | 2026-04-30 | Buy |
| Biosynth | DCA15971 | 5-Acetyl-2-amino-1,3-thiazole | 53159-71-0 | 5g | $413 | 2026-06-04 | Buy |
| Apolloscientific | OR17530 | 5-Acetyl-2-amino-1,3-thiazole 97% | 53159-71-0 | 100mg | $21 | 2026-06-04 | Buy |
1-(2-Amino-1,3-thiazol-5-yl)ethan-1-one Chemical Properties, Uses, Production
Synthesis Reference(s)
The Journal of Organic Chemistry, 49, p. 566, 1984 DOI: 10.1021/jo00177a042
Synthesis
87005-15-0
17356-08-0
53159-71-0
The general procedure for the synthesis of 1-(2-aminothiazol-5-yl)ethanone from 2-bromo-3-oxobutanal and compound (CAS: 17356-08-0) was as follows: 2-bromoacetoacetaldehyde (5 g, 0.03 mol) prepared in Step II was dissolved in ethanol (50 mL). Thiourea (2.76 g, 0.03 mol) was added to this solution and the reaction mixture was stirred at room temperature for 24 hours, followed by heating and refluxing for 3 hours. After completion of the reaction, the mixture was cooled to room temperature and the resulting solid product was separated by filtration. The solid was washed with ethanol and dried under vacuum to afford 1-(2-amino-1,3-thiazol-5-yl)ethanone (P5) as a white solid (2.5 g, 40% yield).
References
[1] Patent: WO2005/68444, 2005, A2. Location in patent: Page/Page column 79
1-(2-Amino-1,3-thiazol-5-yl)ethan-1-one Preparation Products And Raw materials
Raw materials
Preparation Products
1-(2-Amino-1,3-thiazol-5-yl)ethan-1-one Suppliers
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