2-(6-broMopyridin-2-yl)propan-2-ol
- CAS No.
- 638218-78-7
- Chemical Name:
- 2-(6-broMopyridin-2-yl)propan-2-ol
- Synonyms
- 2-(6-bromopyridine) -2-propanol;2-(6-Bromo-2-pyridyl)-2-propanol;2-(6-broMopyridin-2-yl)propan-2-ol;2-Pyridinemethanol, 6-bromo-α,α-dimethyl-;2-(6-broMopyridin-2-yl)propan-2-ol ISO 9001：2015 REACH
- CBNumber:
- CB22560971
- Molecular Formula:
- C8H10BrNO
- Molecular Weight:
- 216.08
- MDL Number:
- MFCD16657880
- MOL File:
- 638218-78-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-(6-bromopyridin-2-yl)propan-2-ol | B429370 | 5g | $60 |
| 2-(6-Bromopyridin-2-yl)propan-2-ol | FB141391 | 100mg | $75 |
| 2-(6-Bromopyridin-2-yl)propan-2-ol | FB141391 | 250mg | $150 |
| 2-(6-Bromopyridin-2-yl)propan-2-ol | FB141391 | 500mg | $260 |
| 2-(6-Bromopyridin-2-yl)propan-2-ol | FB141391 | 1g | $450 |
| More product size | |||
| Boiling point | 273.2±25.0 °C(Predicted) |
|---|---|
| Density | 1.474±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 13.23±0.29(Predicted) |
| Appearance | Colorless to off-white Solid-liquid mixture |
| InChI | InChI=1S/C8H10BrNO/c1-8(2,11)6-4-3-5-7(9)10-6/h3-5,11H,1-2H3 |
| InChIKey | OXSDDDKLMCHNHF-UHFFFAOYSA-N |
| SMILES | CC(C1=NC(Br)=CC=C1)(O)C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
2-(6-broMopyridin-2-yl)propan-2-ol price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B429370 | 2-(6-bromopyridin-2-yl)propan-2-ol | 638218-78-7 | 5g | $60 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB141391 | 2-(6-Bromopyridin-2-yl)propan-2-ol | 638218-78-7 | 100mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB141391 | 2-(6-Bromopyridin-2-yl)propan-2-ol | 638218-78-7 | 250mg | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB141391 | 2-(6-Bromopyridin-2-yl)propan-2-ol | 638218-78-7 | 500mg | $260 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB141391 | 2-(6-Bromopyridin-2-yl)propan-2-ol | 638218-78-7 | 1g | $450 | 2021-12-16 | Buy |
2-(6-broMopyridin-2-yl)propan-2-ol Chemical Properties,Uses,Production
Application
2-(6-bromopyridine)-2-propanol can be used as an organic synthesis intermediate and a pharmaceutical intermediate, mainly in laboratory research and development processes and chemical and pharmaceutical production processes.
Synthesis
626-05-1
67-64-1
638218-78-7
GENERAL STEPS: In a dry 250 mL round-bottomed flask equipped with a stir bar, septum and temperature probe, 1.6 M hexane solution of n-butyllithium (31.2 mL, 50 mmol) was added. The reaction system was cooled to -76 °C in a dry ice-acetone bath. Subsequently, THF (30 mL) was added to the reaction vial and a solution of 2,6-dibromopyridine (11.5 g, 50 mmol) in THF (60 mL) was added slowly dropwise by syringe, controlling the reaction temperature below -60 °C. Stirring of the dark yellow-brown solution was continued in a dry ice bath for 30 min, and then acetone (6 mL, 80 mmol) was added. The reaction mixture was stirred in a dry ice bath for 15 minutes and then slowly warmed to room temperature. After 1 hour of reaction, the reaction was quenched by careful addition of 5% aqueous ammonium chloride solution (50 mL). The reaction mixture was extracted with dichloromethane, the organic phases were combined and the solvent evaporated to give 2-(6-bromopyridin-2-yl)propan-2-ol (10.6 g, 98% yield) as an orange oil. The mass spectrum (MS) showed m/z: 216 and 218 (M+H)+.
References
[1] Patent: WO2009/131814, 2009, A2. Location in patent: Page/Page column 40
[2] Patent: US2013/178478, 2013, A1. Location in patent: Paragraph 0461; 0462
[3] Patent: WO2014/60371, 2014, A1. Location in patent: Page/Page column 76
[4] Chemical Communications, 2016, vol. 52, # 74, p. 11056 - 11059
[5] Patent: WO2004/814, 2003, A1. Location in patent: Page 50
2-(6-broMopyridin-2-yl)propan-2-ol Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 19282 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Henan Alfa Chemical Co., Ltd | +8615838112936 | sale03@alfachem.cn | China | 12830 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
View Lastest Price from 2-(6-broMopyridin-2-yl)propan-2-ol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | 2-(6-broMopyridin-2-yl)propan-2-ol
638218-78-7
|
US $1.10 / g | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-05-13 | 2-(6-broMopyridin-2-yl)propan-2-ol
638218-78-7
|
US $0.00-0.00 / Kg | 1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-12-20 | 2-(6-broMopyridin-2-yl)propan-2-ol
638218-78-7
|
US $1.00 / g | 1g | 99% | g/kg/T | Career Henan Chemical Co |
-
- 2-(6-broMopyridin-2-yl)propan-2-ol
638218-78-7
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 2-(6-broMopyridin-2-yl)propan-2-ol
638218-78-7
- US $0.00-0.00 / Kg
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-(6-broMopyridin-2-yl)propan-2-ol
638218-78-7
- US $1.00 / g
- 99%
- Career Henan Chemical Co
