PYRIFENOX
- CAS No.
- 88283-41-4
- Chemical Name:
- PYRIFENOX
- Synonyms
- RONDO;DORADO;Corado;Korado;NRK 297;FD 4060;POLIGROL;Podigrol;ACR 3651;ro15-1297
- CBNumber:
- CB2256771
- Molecular Formula:
- C14H12Cl2N2O
- Molecular Weight:
- 295.16
- MDL Number:
- MFCD00145192
- MOL File:
- 88283-41-4.mol
- MSDS File:
- SDS
| Melting point | <25℃ |
|---|---|
| Boiling point | bp0.1 >150° |
| Density | 1.3890 (rough estimate) |
| refractive index | 1.5490 (estimate) |
| Flash point | 145 °C |
| storage temp. | 0-6°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 4.76±0.10(Predicted) |
| color | Yellow |
| Merck | 13,8073 |
| Henry's Law Constant | 2.3×102 mol/(m3Pa) at 25℃, Ebert et al. (2023) |
| Major Application |
agriculture environmental |
| InChI | 1S/C14H12Cl2N2O/c1-19-18-14(7-10-3-2-6-17-9-10)12-5-4-11(15)8-13(12)16/h2-6,8-9H,7H2,1H3/b18-14- |
| InChIKey | CKPCAYZTYMHQEX-JXAWBTAJSA-N |
| SMILES | CO\N=C(\Cc1cccnc1)c2ccc(Cl)cc2Cl |
| CAS DataBase Reference | 88283-41-4 |
| FDA UNII | 9QNU6BZ7LO |
| EPA Substance Registry System | Pyrifenox (88283-41-4) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P273-P391-P501-P273-P391-P501 |
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
| RTECS | KM5772000 |
| HS Code | 29333990 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Acute Tox. 4 Oral |
| Toxicity | LD50 in rats (mg/kg): 950 i.p.; 2900 orally; >5000 dermally; LC50 by inhalation in rats: >2.05 mg/l (Zobrist) |
PYRIFENOX price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 45737 | Pyrifenox mixture of Z and E isomers | 88283-41-4 | 100mg | $127 | 2026-04-30 | Buy |
| TRC | TRC-P998855-5MG | Pyrifenox | 88283-41-4 | 5mg | $66 | 2026-06-03 | Buy |
| ChemScene | CS-0079832 | Pyrifenox | 88283-41-4 | 5mg | $144 | 2026-06-04 | Buy |
| AHH | MT-58078 | Poligrol 97% | 0.5g | $330 | 2026-05-26 | Buy | |
| TRC | P998855 | Pyrifenox | 88283-41-4 | 25mg | $155 | 2021-12-16 | Buy |
PYRIFENOX Chemical Properties,Uses,Production
Chemical Properties
This product is a brownish yellow slightly viscous liquid with slightly aromatic odor. b.p.>150℃/13.3 Pa, flash point 145℃, relative density Fang1.28 (20℃), vapor pressure 1.9×10-3 Pa (25℃). 20℃ solubility: acetone, ethyl acetate, chloroform, ether, dimethylformamide, isopropanol, toluene are>200g/L, hexane< ;1g/L, water 115mg/L (pH=7). Stable at room temperature and under UV light. Hydrolyzed at 50°C at pH 3, 7 and 9.
Uses
Agricultural fungicide.
Definition
ChEBI: An oxime O-ether that is the O-methyloxime of 2',4'-dichloro-2-(3-pyridyl)acetophenone. A fungicide used for control of powdery mildew, scab and other fungal pathogens on a range of crops.
Mechanism of action
Systemic with protective and curative action. Disrupts membrane function.
Synthesis
1) Preparation of 2' , 4 ` -dichloro-2 -( 3 - pyridinyl) acetophenone oxime ( 2): 10g of 2', 4'-dichloro-2-(3-pyridinyl) acetophenone (l), 10g of leucoammonium hydrochloride, 12g of anhydrous sodium carbonate and 100ml of Methanol was heated to 60C and the reaction was stirred for 2 h. The resulting mixture was treated with water and extracted with ethyl acetate, the organic layer was dried with anhydrous sodium sulfate, filtered, and concentrated; the residue was recrystallized with acetone/n-hexane to obtain the intermediate (2) 2) Synthesis of 2`,4'-dichloro-2-(3-pyridyl)acetophenone-O-methyl oxime: the intermediate (2) obtained from the reaction of the previous step was dissolved in 25 ml of ethylene glycol bis(methyl ether), with 51 g of sodium hydride (dispersed in oil, content of 5%), and this mixture was stirred at room temperature for 30 min, and then added 2.0 g of Iodomethane, heating to reflux, keep refluxing 4h, the mixture is poured into ice water, acetate ethyl cool extraction, the organic layer is dried with anhydrous sodium sulfate, filtration, filtrate concentration under reduced pressure, the crude product by column chromatography refinement that is the amidinium zebra oxime.
Pesticide Type
Fungicide
PYRIFENOX Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4508 | 55 |
| Shanghai Xilong Biochemical Technology Co., Ltd. | 021-52907766-8042 | China | 9928 | 58 | |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-85201366 18938635012 | sales@regentsciences.com | China | 9384 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8737 | 58 |
| Shanghai Yanze Chemical Co., Ltd. | 15345144255 19901447308 | 260924549@qq.com | China | 9989 | 58 |
