ChemicalBook >> CAS DataBase List >>Methyl 2,3-dichloropropionate

Methyl 2,3-dichloropropionate

CAS No.
3674-09-7
Chemical Name:
Methyl 2,3-dichloropropionate
Synonyms
2,3-dichloropropionate;METHYL-A,B-DICHLOROPROPIONATE;METHYL 2,3-DICHLOROPROPIONATE;Methyl 2,3-dichloropropanoate;Methyl2,3-Dichloropropionate>Methyl 2,3-dichloropropionate,98%;METHYL ALPHA,BETA-DICHLOROPROPIONATE;2,3-dichloro-propanoicacimethylester;2,3-Dichloropropionic Acid Methyl Este;2,3-DICHLOROPROPIONIC ACID METHYL ESTER
CBNumber:
CB2257329
Molecular Formula:
C4H6Cl2O2
Molecular Weight:
157
MDL Number:
MFCD00000944
MOL File:
3674-09-7.mol
MSDS File:
SDS
Last updated:2026-05-12 09:20:59
Product description Number Pack Size Price
Methyl 2,3-dichloropropionate for synthesis 8.18319 10ml $44.2
Methyl 2,3-Dichloropropionate >95.0%(GC) D0408 10g $30
Methyl 2,3-dichloropropanoate >98% M69066 500g $140
Methyl 2,3-dichloropropionate 97% MT-17744 1000g $415
Methyl 2,3-dichloropropionate 97% MT-17744 1000g $415
More product size

Methyl 2,3-dichloropropionate Properties

Boiling point 52-55 °C/2 mmHg (lit.)
Density 1.325 g/mL at 25 °C (lit.)
refractive index n20/D 1.453(lit.)
Flash point 145 °F
storage temp. Store below +30°C.
solubility Soluble in ether, acetone, ethanol.
form liquid
color Colorless to Almost colorless
BRN 1701891
InChI InChI=1S/C4H6Cl2O2/c1-8-4(7)3(6)2-5/h3H,2H2,1H3
InChIKey OFHMODDLBXETIK-UHFFFAOYSA-N
SMILES C(OC)(=O)C(Cl)CCl
CAS DataBase Reference 3674-09-7(CAS DataBase Reference)
NIST Chemistry Reference Propanoic acid, 2,3-dichloro-, methyl ester(3674-09-7)
EPA Substance Registry System Propanoic acid, 2,3-dichloro-, methyl ester (3674-09-7)
UNSPSC Code 12352108

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS08
Signal word  Danger
Hazard statements  H318-H227-H314-H341
Precautionary statements  P201-P202-P210-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P308+P313-P403+P235-P405-P501-P210e-P260h-P303+P361+P353-P305+P351+P338-P501a
Hazard Codes  Xi
Risk Statements  36/37/38-10
Safety Statements  23-24/25-37/39-26-16
RIDADR  1993
WGK Germany  3
TSCA  TSCA listed
HazardClass  8
PackingGroup  III
HS Code  29159000
Storage Class 10 - Combustible liquids
REACH Registrations Active
NFPA 704
2
3 0

Methyl 2,3-dichloropropionate price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.18319 Methyl 2,3-dichloropropionate for synthesis 3674-09-7 10ml $44.2 2024-03-01 Buy
TCI Chemical D0408 Methyl 2,3-Dichloropropionate >95.0%(GC) 3674-09-7 10g $30 2026-04-30 Buy
Synthonix M69066 Methyl 2,3-dichloropropanoate >98% 3674-09-7 500g $140 2026-05-06 Buy
AHH MT-17744 Methyl 2,3-dichloropropionate 97% 1000g $415 2026-05-26 Buy
AHH MT-17744 Methyl 2,3-dichloropropionate 97% 1000g $415 2026-05-25 Buy
Product number Packaging Price Buy
8.18319 10ml $44.2 Buy
D0408 10g $30 Buy
M69066 500g $140 Buy
MT-17744 1000g $415 Buy
MT-17744 1000g $415 Buy

Methyl 2,3-dichloropropionate Chemical Properties,Uses,Production

Chemical Properties

clear colorless to slightly yellow liquid

Uses

Methyl 2,3-dichloropropionate can be used to produce 2-chloro-acrylic acid methyl ester at Heating. It is used as pharmaceutical intermediate.

Application

Methyl 2,3-Dichloropropanoate is a useful reagent in preparation of oxidative fragmentation and coupling of catharanthine analogs to vindoline.

Synthesis

Preparation of Methyl 2,3-dichloropropanoate:
Methyl acrylate (2366 g, 27.5 mol) and dimethylformamide (DMF) (40 g, 0.55 mol) was placed in a 3-liter three necked flask fitted with a stirrer, thermometer, inlet tube and gas trap. Chlorine (950 g, 0.48 mol) was passed into the methyl acrylate rapidly over a period of ten hours while the temperature was kept below 40°C. Reaction progress was monitored by gas chromatography (GC). When it seemed that 50 percent of chlorine was consumed, the reaction was stopped. The reaction mass was taken for distillation to separate methylacrylate and Methyl 2,3-dichloropropanoate. The contents were subjected to vacuum distillation. Methyl 2,3-dichloropropanoate was collected distilling at 70°C with 15mm.Yield (%):77.2, Purity (%) = 98.

Methyl 2,3-dichloropropionate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 181)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8738 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-173 9270 1263 1057@dideu.com China 4000 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Capot Chemical Co.,Ltd.
+8613336195806 sales@capot.com China 29640 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-2158073036 info@dakenam.com China 13901 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21588 55
AB PharmaTech,LLC
323-480-4688 sales@acrospharmatech.com United States 989 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Changzhou Ansciep Chemical Co., Ltd.
+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58

View Lastest Price from Methyl 2,3-dichloropropionate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 2,3-dichloropropionate pictures 2026-03-31 Methyl 2,3-dichloropropionate
3674-09-7
US $100.00 / g 1000g 98% 10tons Puyang Huicheng Electronic Materials Co., Ltd.
Methyl 2,3-dichloropropionate pictures 2026-03-20 Methyl 2,3-dichloropropionate
3674-09-7
US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
Methyl 2,3-dichloropropanoate pictures 2025-09-25 Methyl 2,3-dichloropropanoate
3674-09-7
US $200.00-1.00 / KG 1KG 99%, 99.5% Sublimated g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
METHYL 2,3-DICHLOROPROPIONATE METHYL-A,B-DICHLOROPROPIONATE METHYL ALPHA,BETA-DICHLOROPROPIONATE 2,3-DICHLOROPROPIONIC ACID METHYL ESTER 2,3-dichloro-propanoicacimethylester Methyl 2,3-dichloropropanoate Propionic acid, 2,3-dichloro-, methyl ester METHYL-2,3-DICHLOROPROPIONATE, 1000MG, N EAT Methyl 2,3-dichloropropionate, tech., 70% Propanoic acid, 2,3-dichloro-, methyl ester 2,3-dichloro-propanoic acid methyl ester Methyl 2,3-dichloropropionate,98% Methyl 2,3-dichloropropionate,70%,tech. Methyl 2,3-dichloropropionate, tech., 70% 25ML METHYL 2,3-DICHLOROPROPIONATE FOR SYNTHE Methyl2,3-Dichloropropionate> 2,3-dichloropropionate Propanoic acid, 2,3-dichloro-, methyl ester (9CI, ACI) 2,3-dichloro-Propanoic acid methyl ester (9CI ACI) 2,3-Dichloropropionic Acid Methyl Este 3674-09-7 648-19-2 674-09-7 3674-09-07 ClCH2CHClCOOCH3 Alpha Sort M MAlphabetic META - METH Volatiles/ Semivolatiles