N-Methoxy-N-Methyltetrahydropyran-4-carboxaMide
- CAS No.
- 156353-01-4
- Chemical Name:
- N-Methoxy-N-Methyltetrahydropyran-4-carboxaMide
- Synonyms
- N-methoxy-N-methyloxane-4-carboxamide;N-Methoxy-N-Methyltetrahydropyran-4-carboxaMide;tert-butyl 3-allyl-3-hydroxyazetidine-11-carboxylate;2H-Pyran-4-carboxamide, tetrahydro-N-methoxy-N-methyl-;Tetrahydro-pyran-4-carboxylic acid methoxy-methyl-amide
- CBNumber:
- CB22597429
- Molecular Formula:
- C8H15NO3
- Molecular Weight:
- 173.21
- MDL Number:
- MFCD07370048
- MOL File:
- 156353-01-4.mol
| Product description | Number | Pack Size | Price |
| N-Methoxy-N-methyltetrahydropyran-4-carboxamide | M341683 | 50mg | $45 |
| N-Methoxy-N-methyltetrahydropyran-4-carboxamide | M341683 | 500mg | $265 |
| N-Methoxy-N-methyltetrahydro-2H-pyran-4-carboxamide | CS-0037535 | 1g | $192 |
| N-Methoxy-N-methyltetrahydropyran-4-carboxamide 95% | 116000 | 1g | $224 |
| N-Methoxy-N-methyltetrahydropyran-4-carboxamide 95% | 116000 | 5g | $840 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P310+P330-P405 |
N-Methoxy-N-Methyltetrahydropyran-4-carboxaMide price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M341683 | N-Methoxy-N-methyltetrahydropyran-4-carboxamide | 156353-01-4 | 50mg | $45 | 2021-12-16 | Buy |
| TRC | M341683 | N-Methoxy-N-methyltetrahydropyran-4-carboxamide | 156353-01-4 | 500mg | $265 | 2021-12-16 | Buy |
| ChemScene | CS-0037535 | N-Methoxy-N-methyltetrahydro-2H-pyran-4-carboxamide | 156353-01-4 | 1g | $192 | 2021-12-16 | Buy |
| Matrix Scientific | 116000 | N-Methoxy-N-methyltetrahydropyran-4-carboxamide 95% | 156353-01-4 | 1g | $224 | 2021-12-16 | Buy |
| Matrix Scientific | 116000 | N-Methoxy-N-methyltetrahydropyran-4-carboxamide 95% | 156353-01-4 | 5g | $840 | 2021-12-16 | Buy |
N-Methoxy-N-Methyltetrahydropyran-4-carboxaMide Chemical Properties,Uses,Production
Synthesis
110238-91-0
6638-79-5
156353-01-4
1. Methyl tetrahydropyran-4-carboxylate (1.33 mL, 10.0 mmol) was dissolved in anhydrous THF (20 mL), N,O-dimethylhydroxylamine hydrochloride (1.51 g, 15.5 mmol) was added, and mixed with stirring. 2. Under argon protection, the reaction system was cooled to -30 °C, THF solution of isopropylmagnesium chloride (2.0 mol/L, 15.0 mL, 30.0 mmol) was slowly added dropwise, and the reaction was stirred for 1 hour keeping the temperature at -5 °C. The reaction was then stirred for 1 hour. 3. After completion of the reaction, the reaction was quenched by adding water to the mixture and the organic phase was extracted with ethyl acetate. 4. The organic layer was washed with saturated brine, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to remove the solvent. 5. The crude product was purified by distillation under reduced pressure to afford N-methoxy-N-methyltetrahydropyran-4-carboxamide (1.00 g, 58% yield). 6. The product was characterized as follows: boiling point 125-129 °C/8.0 hPa; 1H NMR (CDCl3, δ ppm): 1.57-1.66 (m, 2H), 1.77-1.93 (m, 2H), 2.85-2.94 (m, 1H), 3.18 (s, 3H), 3.44 (ddd, J = 2.4, 11.9, 11.9 Hz, 2H), 3.69 (s, 2H), 3.44 (ddd, J = 2.4, 11.9, 11.9 Hz, 2H). 2H), 3.69 (s, 3H), 4.00 (ddd, J = 2.4, 11.9, 11.9 Hz, 2H).
References
[1] Patent: WO2007/15528, 2007, A1. Location in patent: Page/Page column 230
[2] Patent: EP1894930, 2008, A1. Location in patent: Page/Page column 31
[3] Patent: EP1921077, 2017, B1. Location in patent: Paragraph 0742
[4] MedChemComm, 2016, vol. 7, # 5, p. 1016 - 1021
[5] Patent: WO2011/50016, 2011, A1. Location in patent: Page/Page column 99-100
N-Methoxy-N-Methyltetrahydropyran-4-carboxaMide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Shanghai Rlavie Technology Co ltd | +86-021-67759270 +8617717059219 | sales@rlavie.com | China | 1030 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30227 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9984 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | sales@bicbiotech.com | China | 5994 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
View Lastest Price from N-Methoxy-N-Methyltetrahydropyran-4-carboxaMide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2022-04-22 | N-Methoxy-N-methyltetrahydropyran-4-carboxamide
156353-01-4
|
US $0.00-0.00 / kg | 0.0001kg | 98%min | 100kgs/month | Shanghai Rlavie Technology Co ltd |
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- N-Methoxy-N-methyltetrahydropyran-4-carboxamide
156353-01-4
- US $0.00-0.00 / kg
- 98%min
- Shanghai Rlavie Technology Co ltd
