3H-IMidazo[4,5-c]pyridine-6-carboxylic acid, Methyl ester
![3H-IMidazo[4,5-c]pyridine-6-carboxylic acid, Methyl ester Structure](CAS/GIF/82523-07-7.gif)
- CAS No.
- 82523-07-7
- Chemical Name:
- 3H-IMidazo[4,5-c]pyridine-6-carboxylic acid, Methyl ester
- Synonyms
- Methyl 3h-iMidazo[4,5-c]pyridine-6-carboxylate;METHYL IMIDAZO<4,5-C>PYRIDINE-3-CARBOXYLATE;methyl 1H-imidazo[4,5-c]pyridine-6-carboxylate;1H-Imidazo[4,5-c]pyridine-6-carboxylic acid, methyl ester;3H-IMidazo[4,5-c]pyridine-6-carboxylic acid, Methyl ester
- CBNumber:
- CB22607865
- Molecular Formula:
- C8H7N3O2
- Molecular Weight:
- 177.16
- MDL Number:
- MFCD11656494
- MOL File:
- 82523-07-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H320-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| HS Code | 2933998090 |
3H-IMidazo[4,5-c]pyridine-6-carboxylic acid, Methyl ester price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR962867 | 3H-Imidazo[4,5-c]pyridine-6-carboxylic acid methyl ester 95% | 82523-07-7 | 100mg | $26 | 2026-06-04 | Buy |
| Apolloscientific | OR962867 | 3H-Imidazo[4,5-c]pyridine-6-carboxylic acid methyl ester 95% | 82523-07-7 | 250mg | $43 | 2026-06-04 | Buy |
| Apolloscientific | OR962867 | 3H-Imidazo[4,5-c]pyridine-6-carboxylic acid methyl ester 95% | 82523-07-7 | 1g | $160 | 2026-06-04 | Buy |
| Matrix Scientific | 312343 | Methyl 3H-imidazo[4,5-c]pyridine-6-carboxylate | 82523-07-7 | 250.00mg | $41 | 2026-05-19 | Buy |
| Matrix Scientific | 312343 | Methyl 3H-imidazo[4,5-c]pyridine-6-carboxylate | 82523-07-7 | 1.00g | $136 | 2026-05-19 | Buy |
3H-IMidazo[4,5-c]pyridine-6-carboxylic acid, Methyl ester Chemical Properties, Uses, Production
Synthesis
![(S)-Methyl 4,5,6,7-tetrahydro-3h-iMidazo[4,5-c]pyridine-6-carboxylate DiHCl](/CAS/20150408/GIF/114786-39-9.gif)
114786-39-9
121-44-8
![3H-IMidazo[4,5-c]pyridine-6-carboxylic acid, Methyl ester](/CAS/GIF/82523-07-7.gif)
82523-07-7
The general procedure for the synthesis of methyl 3H-imidazo[4,5-c]pyridine-6-carboxylate from (S)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid methyl ester dihydrochloride (156.5 g, 0.62 mol) and triethylamine (445.0 g, 4.4 mol, 7.0 equiv) was as follows: selenium dioxide ( 158.2 g, 1.43 mol, 2.3 equiv) and polyphosphoric acid methyl ether (PPSE) (15.0 g) were added to carbon tetrachloride (CCl4) (1.5 L). After cooling to room temperature, the mixture was refluxed for 6 hours. After completion of the reaction, the solvent was removed under reduced pressure and the residue was suspended in methanol (1.5 L) and the pH was adjusted to 8 by addition of triethylamine. the brown solid was collected by filtration and washed well with methanol. The resulting brown solid (117.0 g) was recrystallized. The product was dissolved in hot N,N-dimethylformamide (DMF) (2 L) and hot filtered to remove the black selenium salt by-product. After cooling to room temperature, the target product crystallized as a yellow solid (51.3 g, 47% yield, 95% purity). The product was characterized as follows: 1H NMR (DMSO-d6): δ 13.20 (br s, 1H), 9.02 (s, 1H), 8.58 (s, 1H), 8.31 (s, 1H), 3.89 (s, 3H); LCMS: Rt = 1.33 min, [M + 1]+ = 178.1 m/z.
References
[1] Patent: WO2004/39803, 2004, A2. Location in patent: Page 57
3H-IMidazo[4,5-c]pyridine-6-carboxylic acid, Methyl ester Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Ningbo Materials-X Co., Ltd | 0574-87487840-805 15888368997 | China | 473 | 55 | |
| Chengdu J&B Technology Co., Ltd. | 028-61186694 15608078506 | 609128801@qq.com | China | 853 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Wuxi AppTec | 022-59987777 13552403979 | jia_guoqiang@wuxiapptec.com | China | 22344 | 58 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15078 | 58 |
| Yujinpharma(Tianjin) Technology Co.,Ltd. | 13370351217 kungfu1217@1 | kungfu1217@163.com | China | 7991 | 58 |
| 3A Chemicals | 400-668-9898 | service@3achem.com | China | 20535 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
