Cyclopentanepropanoic acid, α-[(forMylhydroxyaMino)Methyl]-, 2-[5-fluoro-6-[(9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-2-Methyl-4-pyriMidinyl]hydrazide, (αR)-
- CAS No.
- 1152107-25-9
- Chemical Name:
- Cyclopentanepropanoic acid, α-[(forMylhydroxyaMino)Methyl]-, 2-[5-fluoro-6-[(9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-2-Methyl-4-pyriMidinyl]hydrazide, (αR)-
- Synonyms
- Lanopepden;GSK-1322322;GSK-322);GSK132232;GSK-1322322 (Lanopepden;LANOPEPDEN (GSK 1322322);GSK-1322322(Lanopepden/GSK-322);GSK 1322322|||GSK-1322322B|||GSK-1322322J;N-((R)-2-(Cyclopentylmethyl)-3-(2-(5-fluoro-6-((S)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl)-2-methylpyrimidin-4-yl)hydrazinyl)-3-oxopropyl)-N-hydroxyformamide;Cyclopentanepropanoic acid, α-[(formylhydroxyamino)methyl]-, 2-[5-fluoro-6-[(9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-2-methyl-4-pyrimidinyl]hydrazide, (αR)-
- CBNumber:
- CB22631741
- Molecular Formula:
- C22H34FN7O4
- Molecular Weight:
- 479.56
- MDL Number:
- MFCD20526985
- MOL File:
- 1152107-25-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Cyclopentanepropanoic acid, α-[(forMylhydroxyaMino)Methyl]-, 2-[5-fluoro-6-[(9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-2-Methyl-4-pyriMidinyl]hydrazide, (αR)- Properties
| Density | 1.36±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| pka | 8.60±0.69(Predicted) |
| color | Off-white to light yellow |
| FDA UNII | 12M6KFD07E |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Cyclopentanepropanoic acid, α-[(forMylhydroxyaMino)Methyl]-, 2-[5-fluoro-6-[(9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-2-Methyl-4-pyriMidinyl]hydrazide, (αR)- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | CWB10725 | Lanopepden | 1152107-25-9 | 1mg | $392.65 | 2026-06-04 | Buy |
| Biosynth | CWB10725 | Lanopepden | 1152107-25-9 | 5mg | $1276.1 | 2026-06-04 | Buy |
| Biosynth | CWB10725 | Lanopepden | 1152107-25-9 | 10mg | $2041.8 | 2026-06-04 | Buy |
| Biosynth | CWB10725 | Lanopepden | 1152107-25-9 | 25mg | $3828.5 | 2026-06-04 | Buy |
| Biosynth | CWB10725 | Lanopepden | 1152107-25-9 | 50mg | $6125.5 | 2026-06-04 | Buy |
Cyclopentanepropanoic acid, α-[(forMylhydroxyaMino)Methyl]-, 2-[5-fluoro-6-[(9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-2-Methyl-4-pyriMidinyl]hydrazide, (αR)- Chemical Properties, Uses, Production
Uses
Lanopepden (GSK 1322322) is a peptidyl peptidase (PDF) inhibitor. Lanopepden inhibits PDF activity, preventing bacterial protein synthesis, thereby exerting antibacterial activity. Lanopepden is primarily effective against Gram-positive bacteria. Lanopepden is used in the study of acute bacterial skin and skin structure infections[1].
References
[1] Peyrusson F, et al. Cellular pharmacokinetics and intracellular activity of the novel peptide deformylase inhibitor GSK1322322 against Staphylococcus aureus laboratory and clinical strains with various resistance phenotypes: studies with human THP-1 monocytes and J774 murine macrophages. Antimicrob Agents Chemother. 2015 Sep;59(9):5747-60. DOI:10.1128/AAC.00827-15
Cyclopentanepropanoic acid, α-[(forMylhydroxyaMino)Methyl]-, 2-[5-fluoro-6-[(9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-2-Methyl-4-pyriMidinyl]hydrazide, (αR)- Preparation Products And Raw materials
Raw materials
Preparation Products
Cyclopentanepropanoic acid, α-[(forMylhydroxyaMino)Methyl]-, 2-[5-fluoro-6-[(9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-2-Methyl-4-pyriMidinyl]hydrazide, (αR)- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6378 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6288 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
| Guangzhou Ruidi Biotechnology Co., Ltd. | 020-82099279 18988941402 | sales@ubiochem.com | China | 9998 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | info@chemextension.com | China | 42052 | 58 |





