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ChemicalBook >> CAS DataBase List >>tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate

tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate

tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate Structure
tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate structure
CAS No.
147353-95-5
Chemical Name:
tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate
Synonyms
N-Boc-2-amino-2-(4-chlorophenyl)ethan-1-ol;tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate;tert-butyl N-[1-(4-chlorophenyl)-2-hydroxyethyl]carbamate;Carbamic acid, N-[1-(4-chlorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester
CBNumber:
CB22650795
Molecular Formula:
C13H18ClNO3
Molecular Weight:
271.74
MDL Number:
MFCD24387088
MOL File:
147353-95-5.mol
MSDS File:
SDS
Last updated:2026-05-28 00:10:26
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tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate Properties

storage temp. 2-8°C

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338

tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 301953 tert-Butyl (1-(4-chlorophenyl)-2-hydroxyethyl)carbamate 147353-95-5 100.00mg $86 2026-05-19 Buy
Matrix Scientific 301953 tert-Butyl (1-(4-chlorophenyl)-2-hydroxyethyl)carbamate 147353-95-5 250.00mg $128 2026-05-19 Buy
Matrix Scientific 301953 tert-Butyl (1-(4-chlorophenyl)-2-hydroxyethyl)carbamate 147353-95-5 1.00g $321 2026-05-19 Buy
Synthonix B57105 tert-Butyl (1-(4-chlorophenyl)-2-hydroxyethyl)carbamate 97% 147353-95-5 100mg $1545 2026-05-06 Buy
Synthonix B57105 tert-Butyl (1-(4-chlorophenyl)-2-hydroxyethyl)carbamate 97% 147353-95-5 250mg $1955 2026-05-06 Buy
Product number Packaging Price Buy
301953 100.00mg $86 Buy
301953 250.00mg $128 Buy
301953 1.00g $321 Buy
B57105 100mg $1545 Buy
B57105 250mg $1955 Buy

tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate Chemical Properties,Uses,Production

Synthesis

2-aMino-2-(4-chlorophenyl)ethanol

179811-64-4

Di-tert-butyl dicarbonate

24424-99-5

tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate

147353-95-5

Step 1: Synthesis of tert-butyl (racemic)-(1-(4-chlorophenyl)-2-hydroxyethyl)carbamate: (Racemic)-2-amino-2-(4-chlorophenyl)ethanol (2 g, 1.65 mmol, prepared according to the method described in WO2009/47563A1) was dissolved in THF (20 ml), and di-tert-butyl dicarbonate (Boc anhydride. 2.84 ml, 12.24 mmol) and triethylamine (2.436 ml, 17.48 mmol). The reaction mixture was stirred at room temperature and kept overnight. After completion of the reaction, the mixture was concentrated in vacuum and extracted by dilution with ethyl acetate (EtOAc) and 1N hydrochloric acid (HCl). The organic phase was washed with saturated brine, dried over anhydrous sodium sulfate (Na2SO4) and subsequently concentrated in vacuum to give the title compound as a viscous solid (2.8 g, 88% yield).1H NMR (500 MHz, CDCl3) data were as follows: δ 7.34 (2H, m), 7.27 (1H, d), 5.35 (1H, m), 4.75 (1H, m), 4.75 (1H, m). 3.75-3.90 (2H, m), 1.44 (9H, s).

References

[1] Patent: WO2012/69852, 2012, A1. Location in patent: Page/Page column 137-138
[2] Patent: WO2009/47563, 2009, A1. Location in patent: Page/Page column 99

tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate synthesis

179811-64-4
24424-99-5
147353-95-5
Synthesis of tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate from 2-aMino-2-(4-chlorophenyl)ethanol and Di-tert-butyl dicarbonate

tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate Preparation Products And Raw materials

Raw materials

2-aMino-2-(4-chlorophenyl)ethanol Di-tert-butyl dicarbonate Tetrahydrofuran Triethylamine

Preparation Products

tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate Suppliers

Global( 22)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Litong Chemical Technology Co.,Ltd. 13598610367 0373-7129549 2468833170@qq.com China 932 58
ShangHai KenEn Chemical Technology Co., Ltd. 13120367189;18621755571 mychess007@163.com China 1994 55
BePharm Ltd 400-685-9117 market@bepharm.com China 15081 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Bejing Famous Pharmaceutical Technology Co., Ltd. 010-80339217; 13331045123 2559355526@qq.com China 14180 58
Cool Pharm, Ltd 021-58581007 18019463053 sales@coolpharm.com China 9999 58
Zhengzhou Alpha Chemical Co. LTD 0371-53732842 13383863444 3838551451@qq.com China 9997 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
Hubei Co-prosperity Medicine Technonlogy Co., Ltd 2383948258 19172820304 2383948258@qq.com China 12983 58
Bide Pharmatech Ltd. 400-6005915 sales@picasso-e.com China 39662 58
Supplier Advantage
Shanghai Litong Chemical Technology Co.,Ltd. 58
ShangHai KenEn Chemical Technology Co., Ltd. 55
BePharm Ltd 60
Amadis Chemical Company Limited 58
Bejing Famous Pharmaceutical Technology Co., Ltd. 58
Cool Pharm, Ltd 58
Zhengzhou Alpha Chemical Co. LTD 58
Energy Chemical 58
Hubei Co-prosperity Medicine Technonlogy Co., Ltd 58
Bide Pharmatech Ltd. 58

147353-95-5(tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate)Related Search:

Benzalkonium chloride
tert-butyl 1-(4-chlorophenyl)-2-hydroxyethylcarbaMate Carbamic acid, N-[1-(4-chlorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester tert-butyl N-[1-(4-chlorophenyl)-2-hydroxyethyl]carbamate N-Boc-2-amino-2-(4-chlorophenyl)ethan-1-ol 147353-95-5