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2',3'-O-Isopropylideneinosine

2',3'-O-Isopropylideneinosine structure

CAS No.: 2140-11-6

Chemical Name:: 2',3'-O-Isopropylideneinosine

Synonyms: 2',3'-Ipr-Ino;-O-Isopropylideneinosine;2',3'-isopropylideneinosine;2',3'-ISOPROPYLIDENEINOSINE;2',3'-O-Isopropyrideneinosine;2',3'-0-lsopropylideneinosine;2‘,3'-O-lsopropylideneinosine;2',3'-O-Isopropylideneinosine;2',3'-O-Isopropylideneinosine;2'-O,3'-O-Isopropylideneinosine

CBNumber:: CB2271080

Molecular Formula:: C13H16N4O5

Molecular Weight:: 308.29

MDL Number:: MFCD00038002

MOL File:: 2140-11-6.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:47

Product description	Number	Pack Size	Price
2',3'-ISOPROPYLIDENEINOSINE Aldrich^CPR	S450715	1 unit	$30.7
2'',3''-ISOPROPYLIDENEINOSINE AldrichCPR	S450715	250MG	$29.8
2',3'-O-Isopropylideneinosine >98.0%(HPLC)	I0704	5g	$25
2'',3''-O-Isopropylideneinosine	I868500	50g	$115
2',3'-O-ISOPROPYLIDENEINOSINE 95.00%	NUC0000565	1G	$117.6
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2',3'-O-Isopropylideneinosine Properties

Melting point	263-272°C
Boiling point	606.6±65.0 °C(Predicted)
Density	1.80±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form	Solid
pka	14.14±0.10(Predicted)
color	White to Off-White
InChI	InChI=1S/C13H16N4O5/c1-13(2)21-8-6(3-18)20-12(9(8)22-13)17-5-16-7-10(17)14-4-15-11(7)19/h4-6,8-9,12,18H,3H2,1-2H3,(H,14,15,19)/t6-,8-,9-,12-/m1/s1
InChIKey	LIEKLUBCIPVWQD-WOUKDFQISA-N
SMILES	OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)O)N=C2)[C@@H]2OC(O[C@H]12)(C)C
CAS DataBase Reference	2140-11-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety Statements	24/25
WGK Germany	3
HS Code	29389090

2',3'-O-Isopropylideneinosine price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	S450715	2',3'-ISOPROPYLIDENEINOSINE Aldrich^CPR	2140-11-6	1 unit	$30.7	2025-07-31	Buy
Sigma-Aldrich	S450715	2'',3''-ISOPROPYLIDENEINOSINE AldrichCPR	2140-11-6	250MG	$29.8	2024-03-01	Buy
TCI Chemical	I0704	2',3'-O-Isopropylideneinosine >98.0%(HPLC)	2140-11-6	5g	$25	2025-07-31	Buy
TRC	I868500	2'',3''-O-Isopropylideneinosine	2140-11-6	50g	$115	2021-12-16	Buy
American Custom Chemicals Corporation	NUC0000565	2',3'-O-ISOPROPYLIDENEINOSINE 95.00%	2140-11-6	1G	$117.6	2021-12-16	Buy

Product number	Packaging	Price	Buy
S450715	1 unit	$30.7	Buy
S450715	250MG	$29.8	Buy
I0704	5g	$25	Buy
I868500	50g	$115	Buy
NUC0000565	1G	$117.6	Buy

2',3'-O-Isopropylideneinosine Chemical Properties,Uses,Production

Chemical Properties

2',3'-O-Isopropylideneinosine is White Solid

Uses

A useful precursor for the preparation of nucleic acids

Uses

2',3'-O-Isopropylideneinosine is an inosine derivative as antiviral, bactericidal, and antitumor agent for immunopotentiating uses.

Synthesis

58-63-9

77-76-9

2140-11-6

To a solution of inosine (0.998 g, 3.72 mmol) in dimethylformamide (DMF, 30 mL) was sequentially added 2,2-dimethoxypropane (1.8 mL, 14.59 mmol) and p-toluenesulfonic acid monohydrate (0.038 g, 0.372 mmol). The reaction mixture was stirred under argon (Ar) protection for 24 hours. Upon completion of the reaction, DMF was removed by evaporation under reduced pressure, followed by alkalinization of the reaction mixture with 3% ammonia solution and evaporation again to dryness. The resulting residue was purified by silica gel column chromatography (eluent: dichloromethane/methanol, 95/5, v/v) to afford the target compound 22 in white foamy form in 80% yield. The product was characterized by 1H-NMR (200 MHz, DMSO-d6): δ 1.34, 1.50 (6H, s, (CH3)2C), 3.6 (2H, t, CH2-5'), 4.37 (1H, m, H-4'), 4.94 (1H, m, H-3'), 5.18 (1H, t, OH-5'), 5.37 (1H, dd. J = 3.7 Hz, H-2'), 6.12 (1H, d, J = 2.4 Hz, H-1'), 8.05 (1H, s, H-2), 8.32 (1H, s, H-8), and 12.44 (1H, br s, NH-3).ESI-MS analysis showed: m/z 309.1 [M + H]+, molecular formula C13H16N4O5, molecular weight 308.29.

References

[1] European Journal of Medicinal Chemistry, 2012, vol. 54, p. 202 - 209
[2] Journal of Medicinal Chemistry, 2018, vol. 61, # 5, p. 2087 - 2103
[3] Journal of Medicinal Chemistry, 2008, vol. 51, # 17, p. 5349 - 5370
[4] Heterocycles, 2013, vol. 87, # 11, p. 2369 - 2384
[5] Chinese Chemical Letters, 2011, vol. 22, # 12, p. 1439 - 1442

2',3'-O-Isopropylideneinosine Preparation Products And Raw materials

Raw materials

Inosine 2,2-Dimethoxypropane N,N-Dimethylformamide p-Toluenesulfonic acid monohydrate

Preparation Products

1-(6-Chloro-9H-purin-9-yl)-1-deoxy-2,3-O-isopropylidene-beta-D-ribofuranuronoyl chloride

2',3'-O-Isopropylideneinosine Suppliers

Global( 161)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou Measure Life Technology Co., LTD	+8613343730176	2924244016@qq.com	China	83	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29852	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Wuhan Chemwonders Technology Inc.	027-85778276	info@chemwonders.com	CHINA	176	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Longyan Tianhua Biological Technology Co., Ltd	0086 18039857276 18039857276		CHINA	2783	58

Supplier	Advantage
Hangzhou Measure Life Technology Co., LTD	58
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Wuhan Chemwonders Technology Inc.	58
Xiamen AmoyChem Co., Ltd	58
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
Antai Fine Chemical Technology Co.,Limited	58
SIMAGCHEM CORP	58
Longyan Tianhua Biological Technology Co., Ltd	58

View Lastest Price from 2',3'-O-Isopropylideneinosine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2022-01-27	2',3'-O-Isopropylideneinosine	US $0.00 / KG	1KG	97.3%	100 tons	Honest Joy Holdings Limited
	2019-07-06	2',3'-O-Isopropylideneinosine 2140-11-6	US $2.00 / KG	1KG	98%	1ton	Career Henan Chemical Co

2',3'-O-Isopropylideneinosine
US $0.00 / KG
97.3%
Honest Joy Holdings Limited

2',3'-O-Isopropylideneinosine
2140-11-6
US $2.00 / KG
98%
Career Henan Chemical Co

2',3'-O-Isopropylideneinosine Spectrum

2',3'-O-Isopropylideneinosine(2140-11-6)MS 2',3'-O-Isopropylideneinosine(2140-11-6)¹HNMR 2',3'-O-Isopropylideneinosine(2140-11-6)¹³CNMR 2',3'-O-Isopropylideneinosine(2140-11-6)IR1 2',3'-O-Isopropylideneinosine(2140-11-6)IR2

2140-11-6(2',3'-O-Isopropylideneinosine)Related Search:

Mesityl oxide Disodium 5'-Inosinate Isoprinosine Dideoxyinosine 6-Hydroxypurine

3-Isopropoxypropylamine 2'-Deoxyinosine 1-METHYL-1H-IMIDAZOLE-4-CARBALDEHYDE (1-Methyl-1H-imidazol-4-yl)methylamine (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol

AICAR 2',3'-O-Isopropylideneguanosine Inosine 1,3-Dioxolane-4-methanol 2,2-Dimethyl-1,3-dioxolane-4-methanol

[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]methanamine 2',3'-O-ISOPROPYLIDENE-5'-TRITYLINOSINE 5-AMINO-1-PROPYL-1H-IMIDAZOLE-4-CARBOXAMIDE

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2',3'-isopropylideneinosine 2',3'-O-Isopropylidene-D-inosine 2'',3''-O-ISOPROPYLIDENEINOSINE,98.0+%(LC) 2',3'-O-(1-Methylethylidene)- Inosine 9-(2,3-O-Isopropylidene-beta-D-ribofuranosyl)hypoxanthine 2'-O,3'-O-Isopropylidene-2-deaminoguanosine 2'-O,3'-O-Isopropylidene-6-hydroxy-6-deaminoadenosine 2'-O,3'-O-Isopropylideneinosine 2',3'-O-Isopropylideneinosine≥ 98% (HPLC) 9-((3aR,4R,6R,6aR)-6-(HydroxyMethyl)-2,2-diMethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-ol -O-Isopropylideneinosine 2',3'-O-Isopropylideneinosine> Inosine, 2',3'-O-(1-methylethylidene)- 2',3'-Ipr-Ino 2',3'-O-Isopropylideneinosine USP/EP/BP 2',3'-O-Isopropyrideneinosine 2',3'-0-lsopropylideneinosine 2‘,3'-O-lsopropylideneinosine 2',3'-O-Isopropylideneinosine 2',3'-ISOPROPYLIDENEINOSINE 2′,3′-O-Isopropylideneinosine, CAS 2140-11-6 2',3'-O-Isopropylideneinosine 2140-11-6 2140-11-06 40-11-6 Heterocycles Biochemistry Nucleosides and their analogs Nucleosides, Nucleotides & Related Reagents Bases & Related Reagents Nucleotides