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1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine

CAS No.
85405-03-4
Chemical Name:
1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine
Synonyms
Butanoyl PAF(solution in ethanol);1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine;1-O-HEXADECYL-2-BUTYRYL-SN-GLYCERO-3-PHOSPHOCHOLINE;C16-04:0 PC;(R)-2-(Butyryloxy)-3-(hexadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
CBNumber:
CB22720649
Molecular Formula:
C28H58NO7P
Molecular Weight:
551.736381
MDL Number:
MFCD02259312
MOL File:
85405-03-4.mol
MSDS File:
SDS
Last updated:2026-05-28 00:06:14

1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine Properties

storage temp. Store at -20°C
solubility DMF: 14 mg/ml; DMSO: 12 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 5 mg/ml
form powder
SMILES [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCC)=O)COCCCCCCCCCCCCCCCC)=O
UNSPSC Code 12352211
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
target organs Central nervous system
WGK Germany  WGK 3
Storage Class 6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects
Hazard Classifications Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 1
STOT SE 3
NFPA 704
3
2 0

1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 60928 Butanoyl PAF ≥98% 85405-03-4 1mg $43 2026-04-30 Buy
Cayman Chemical 60928 Butanoyl PAF ≥98% 85405-03-4 5mg $204 2026-04-30 Buy
Cayman Chemical 60928 Butanoyl PAF ≥98% 85405-03-4 10mg $323 2026-04-30 Buy
Cayman Chemical 60928 Butanoyl PAF ≥98% 85405-03-4 50mg $1073 2026-04-30 Buy
Biosynth KDA40503 C16-04:0 PC 85405-03-4 25mg $1190 2026-06-04 Buy
Product number Packaging Price Buy
60928 1mg $43 Buy
60928 5mg $204 Buy
60928 10mg $323 Buy
60928 50mg $1073 Buy
KDA40503 25mg $1190 Buy

1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine Chemical Properties, Uses, Production

Description

Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes and activate polymorphonuclear leukocytes.1 One of these substances was recently isolated and purified from oxLDL, and identified as azelaoyl PC.2 Butanoyl PAF is a closely related compound which retains at least 10% of the agonist potency of platelet-activating factor (PAF) itself.3 Further, butanoyl PAF is present in oxLDL in amounts more than 100 times greater than enzymatically generated PAF. Butanoyl PAF is therefore one of the important signalling molecules present in oxLDL.

Uses

Butanoyl PAF, a compound closely related to Azelaoyl PC (HY-134154), maintains over 10% of the agonist potency of platelet-activating factor (PAF). Butanoyl PAF's concentration in oxidized low-density lipoprotein surpasses that of enzymatically generated PAF by more than 100-fold[1].

Definition

ChEBI: 1-hexadecyl-2-butanoyl-sn-glycero-3-phosphocholine is a 2-acyl-1-alkyl-sn-glycero-3-phosphocholine in which the alkyl and the acyl groups at positions 1 and 2 are hexadecyl and butanoyl respectively. It is a 2-acyl-1-alkyl-sn-glycero-3-phosphocholine and a butyrate ester.

References

1. Tontonoz, P., Nagy, L., Alvarez, J.G.A., et al. PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL Cell 93(2),241-252(1998).
2. Davies, S.S., Pontsler, A.V., Marathe, G.K., et al. Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor γ ligands and agonists J. Biol. Chem. 276,16015-16023(2001).
3. Marathe, G.K., Davies, S.S., Harrison, K.A., et al. Inflammatory platelet-activating factor-like phospholipids in oxidized low density lipoproteins are fragmented alkyl phosphatidylcholines J. Biol. Chem. 274,28395-28404(1999).

1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine Preparation Products And Raw materials

Raw materials

Preparation Products

1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine Suppliers

Global Suppliers ( 17)
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Chengdu Huachun Technology Co., Ltd 400-1166-196 15982826727 cdhxsj@163.com China 14571 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Creative Enzymes 1-516-855-7709 info@creative-enzymes.com United States 8748 58

85405-03-4 (1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine) Related Search:

1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine 1-O-HEXADECYL-2-BUTYRYL-SN-GLYCERO-3-PHOSPHOCHOLINE;C16-04:0 PC (R)-2-(Butyryloxy)-3-(hexadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate Butanoyl PAF(solution in ethanol) 85405-03-4