(S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt)
- CAS No.
- 799268-73-8
- Chemical Name:
- (S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt)
- Synonyms
- VPC 12249 (S);(S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt);(S)-PHOSPHORIC ACID MONO-[3-(4-BENZYLOXY-PHENYL)-2-OCTADEC-9-ENOYLAMINO-PROPYL] ESTER (AMMONIUM SALT);VPC 12249 (S)
- CBNumber:
- CB22720694
- Molecular Formula:
- C34H55N2O6P
- Molecular Weight:
- 618.8
- MDL Number:
- MFCD22416852
- MOL File:
- 799268-73-8.mol
- MSDS File:
- SDS
(S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt) Chemical Properties, Uses, Production
Uses
VPC 12249 has been used as lysophosphatidic acid (LPA)1/3 receptor antagonist in various experimental studies.
General Description
VPC 12249 is an N-acyl (oleoyl) serine phosphate-based compound.
Biochem/physiol Actions
Lysophosphatidic acids (LPAs) are bioactive lipid mediators. It interacts with at least six specific LPA receptors (LPA1-6) to mediate extracellular signaling pathway. LPA and its receptors (LPA1-3) are implicated in the pathogenesis of radiation pneumonitis (RP). VPC 12249 (S) inhibits the binding ofLPA to LPA1 and LPA3 receptor.
(S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt) Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Chengdu Huachun Technology Co., Ltd | 400-1166-196 15982826727 | cdhxsj@163.com | China | 14571 | 60 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50089 | 58 | |
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 58 |
| Chengdu Huachun Technology Co., Ltd | 60 |
| Aladdin Scientific | 58 |
| Creative Enzymes | 58 |




