4-(2-methoxy-2-oxoethyl)benzoic acid
- CAS No.
- 87524-66-1
- Chemical Name:
- 4-(2-methoxy-2-oxoethyl)benzoic acid
- Synonyms
- 4-(2-methoxy-2-oxoethyl)benzoic acid;4-Carboxy-benzeneacetic acid methyl ester;Benzeneacetic acid, 4-carboxy-, a-methyl ester;Benzeneacetic acid, 4-carboxy-, 1-Methyl ester
- CBNumber:
- CB22734781
- Molecular Formula:
- C10H10O4
- Molecular Weight:
- 194.19
- MDL Number:
- MFCD18782075
- MOL File:
- 87524-66-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-(2-methoxy-2-oxoethyl)benzoic acid | MDA52466 | 5g | $295 |
| 4-(2-Methoxy-2-oxoethyl)benzoic acid 97% | AS110681 | 1g | $64 |
| 4-(2-Methoxy-2-oxoethyl)benzoic acid 97% | AS110681 | 5g | $227 |
| 4-(2-Methoxy-2-oxoethyl)benzoic acid 97% | AS110681 | 25g | $902 |
| 4-(2-Methoxy-2-oxoethyl)benzoic acid 95+% | M52480 | 100mg | $20 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H319 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
4-(2-methoxy-2-oxoethyl)benzoic acid price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | MDA52466 | 4-(2-methoxy-2-oxoethyl)benzoic acid | 87524-66-1 | 5g | $295 | 2026-06-04 | Buy |
| Activate Scientific | AS110681 | 4-(2-Methoxy-2-oxoethyl)benzoic acid 97% | 87524-66-1 | 1g | $64 | 2026-06-04 | Buy |
| Activate Scientific | AS110681 | 4-(2-Methoxy-2-oxoethyl)benzoic acid 97% | 87524-66-1 | 5g | $227 | 2026-06-04 | Buy |
| Activate Scientific | AS110681 | 4-(2-Methoxy-2-oxoethyl)benzoic acid 97% | 87524-66-1 | 25g | $902 | 2026-06-04 | Buy |
| Synthonix | M52480 | 4-(2-Methoxy-2-oxoethyl)benzoic acid 95+% | 87524-66-1 | 100mg | $20 | 2026-05-06 | Buy |
4-(2-methoxy-2-oxoethyl)benzoic acid Chemical Properties,Uses,Production
Synthesis
67-56-1
501-89-3
87524-66-1
General procedure for the synthesis of methyl 4-carboxyphenylacetate from methanol and 4-(carboxymethyl)benzoic acid: to a solution of 4-(carboxymethyl)benzoic acid (1.00 g, 5.55 mmol, 1 eq.) in methanol (11 mL) was added thionyl chloride (0.020 mL, 0.28 mmol, 5 mol%). The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the solvent was removed by evaporation under reduced pressure and the residue was dissolved in methyl tertiary butyl ether (MTBE). It was washed three times sequentially with saturated NaHCO3 solution and once more with water. The bicarbonate and aqueous phase extracts were combined and acidified with 1N HCl until the monomethyl ester precipitated. The mixture was extracted three times with MTBE, the organic layers were combined and dried with anhydrous Na2SO4. Concentration of the organic layer under reduced pressure afforded 4-(2-methoxy-2-oxoethyl)benzoic acid (12) (0.985 g, 91% yield) as a white solid.1H NMR (CDCl3, 400 MHz) δ 8.08 (d, 2H, J = 8.4Hz), 7.40 (d, 2H, J = 8.4Hz), 3.72 (s, 5H). The data obtained are in agreement with those reported in the literature WO2005/12220.
References
[1] Patent: WO2016/199111, 2016, A1. Location in patent: Paragraph 00146-00147
[2] Journal of Chemical Research - Part S, 1999, # 6, p. 378 - 379
[3] Patent: WO2005/12220, 2005, A2. Location in patent: Page/Page column 113
[4] Patent: WO2013/41407, 2013, A1. Location in patent: Page/Page column 34
[5] Patent: WO2014/125426, 2014, A1. Location in patent: Page/Page column 40
4-(2-methoxy-2-oxoethyl)benzoic acid Preparation Products And Raw materials
4-(2-methoxy-2-oxoethyl)benzoic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
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