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Nintedanib

CAS No.
1174335-83-1
Chemical Name:
Nintedanib
Synonyms
Methyl (E)-1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;(3E)-1-(2-Chloroacetyl)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester;Nintedanib impurities2;Nintedanib Impurity 148;Intedanib(Nintedanib) Impurity 17;Nintedanib Impurity 2 (Intedanib Impurity 2);(E)-1-cholroacetyl-3-(methoxy(phenyl)methylene)-2-indolone-6-methylformate;methyl 1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;methyl-1 -(chloroacetyl)-3- [methoxy(phenyl)methylene]-2-oxoindoline-6-carboxylate;(E)-methyl 1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
CBNumber:
CB22741480
Molecular Formula:
C20H16ClNO5
Molecular Weight:
385.8
MDL Number:
MOL File:
1174335-83-1.mol
MSDS File:
SDS
Last updated:2026-05-28 00:05:56

Nintedanib Properties

Boiling point 571.9±50.0 °C(Predicted)
Density 1.374±0.06 g/cm3(Predicted)
storage temp. Storage temp. 2-8°C
pka -2.57±0.20(Predicted)
Appearance Light yellow to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338
REACH Registrations Active

Nintedanib price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA008TI9 (E)-Methyl 1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 95% 1174335-83-1 250mg $1024 2026-05-28 Buy
ACHEMBLOCK X216293 methyl (3e)-1-(2-chloroacetyl)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1h-indole-6-carboxylate 96% 1174335-83-1 100MG $455 2026-05-27 Buy
ACHEMBLOCK X216293 methyl (3e)-1-(2-chloroacetyl)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1h-indole-6-carboxylate 96% 1174335-83-1 250MG $730 2026-05-27 Buy
ACHEMBLOCK X216293 methyl (3e)-1-(2-chloroacetyl)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1h-indole-6-carboxylate 96% 1174335-83-1 1G $1870 2026-05-27 Buy
ChemScene CS-M3032 1H-Indole-6-carboxylicacid,1-(2-chloroacetyl)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-,methylester,(3E)- 1174335-83-1 100mg $258 2021-12-16 Buy
Product number Packaging Price Buy
AA008TI9 250mg $1024 Buy
X216293 100MG $455 Buy
X216293 250MG $730 Buy
X216293 1G $1870 Buy
CS-M3032 100mg $258 Buy

Nintedanib Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 49)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7545 61
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 15250997978 1511893459@qq.com China 4777 55
Changzhou Fang Nan Medical Technology Co., Ltd. 0519-85283268 China 116 55
ShangHai Movin Pharmaceutical Co., Ltd. 13681854265 info@moenpharm.com China 488 55
BOC Sciences 16314854226 info@bocsci.com United States 9909 65
Shanghai Brain Biotechnology Co., Ltd. 13564638271 shhjiang1977@163.com China 2983 55
Zhengzhou Acme Chemical Co., Ltd. 0371-0371-55629727 13323845623 2885676761@qq.com China 9957 58
Hubei widely chemical technology Co., Ltd. 027-83991130 18627774460 1718093273@QQ.COM China 1617 58

Nintedanib Spectrum

methyl-1 -(chloroacetyl)-3- [methoxy(phenyl)methylene]-2-oxoindoline-6-carboxylate 1H-Indole-6-carboxylic acid, 1-(2-chloroacetyl)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-, methyl ester, (3E)- (3E)-1-(2-Chloroacetyl)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester methyl 1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 1-(2-chloroacetyl)-3-[1-methoxy-1-phenylmeth-(E)-ylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester Nintedanib Impurity 2 (Intedanib Impurity 2) (E)-methyl 1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate (E)-1-cholroacetyl-3-(methoxy(phenyl)methylene)-2-indolone-6-methylformate Nintedanib impurities2 Intedanib(Nintedanib) Impurity 17 Methyl (3E)-1-(2-chloroacetyl)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylate Nintedanib Impurity 148 Methyl (E)-1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Methyl (E)-1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate (Nintedanib impurity) 1174335-83-1