Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>(-)-Corey Lactone Benzoate

(-)-Corey Lactone Benzoate

(-)-Corey Lactone Benzoate Structure
(-)-Corey Lactone Benzoate structure
CAS No.
39746-00-4
Chemical Name:
(-)-Corey Lactone Benzoate
Synonyms
(3aR,4S,5R,6aS)-4-(hydroxyMethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate;BCOD;(-)corey lactone benzoate;PGX 4;COREY'S LACTONE;lactone benzoate;(-) Benzoyl lactone;Iloprost Impurity 16;Benzoic acid lactone;BENZOYL COREY LACTONE
CBNumber:
CB2282525
Molecular Formula:
C15H16O5
Molecular Weight:
276.29
MDL Number:
MFCD00674102
MOL File:
39746-00-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:07:28
Product description Number Pack Size Price
(-)-Corey Lactone Benzoate >98.0%(HPLC) C2605 1g $233
(-)-Corey Lactone Benzoate >98.0%(HPLC) C2605 200mg $72
Corey Lactone Benzoate ≥98% 10007983 50mg $29
Corey Lactone Benzoate ≥98% 10007983 100mg $54
Corey Lactone Benzoate ≥98% 10007983 250mg $128
More product size
Request For Quotation

(-)-Corey Lactone Benzoate Properties

Melting point 116-120 °C
alpha -80 º (c=0.8, CHCl3 25 ºC)
Boiling point 379.19°C (rough estimate)
Density 1.2379 (rough estimate)
refractive index 1.5000 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 14.79±0.10(Predicted)
color White to Pale Yellow
InChI InChI=1S/C15H16O5/c16-8-11-10-6-14(17)19-12(10)7-13(11)20-15(18)9-4-2-1-3-5-9/h1-5,10-13,16H,6-8H2/t10-,11-,12+,13-/m1/s1
InChIKey OBRRYUZUDKVCOO-FVCCEPFGSA-N
SMILES O1C(=O)C[C@]2([H])[C@@H](CO)[C@H](OC(=O)C3=CC=CC=C3)C[C@]12[H]
CAS DataBase Reference 39746-00-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36/37/39-26
HS Code  29321900

(-)-Corey Lactone Benzoate price More Price(83)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C2605 (-)-Corey Lactone Benzoate >98.0%(HPLC) 39746-00-4 1g $233 2026-04-30 Buy
TCI Chemical C2605 (-)-Corey Lactone Benzoate >98.0%(HPLC) 39746-00-4 200mg $72 2026-04-30 Buy
Cayman Chemical 10007983 Corey Lactone Benzoate ≥98% 39746-00-4 50mg $29 2026-04-30 Buy
Cayman Chemical 10007983 Corey Lactone Benzoate ≥98% 39746-00-4 100mg $54 2026-04-30 Buy
Cayman Chemical 10007983 Corey Lactone Benzoate ≥98% 39746-00-4 250mg $128 2026-04-30 Buy
Product number Packaging Price Buy
C2605 1g $233 Buy
C2605 200mg $72 Buy
10007983 50mg $29 Buy
10007983 100mg $54 Buy
10007983 250mg $128 Buy

(-)-Corey Lactone Benzoate Chemical Properties,Uses,Production

Chemical Properties

Colorless crystalline powder

Uses

(-)-Corey Lactone Benzoate is a corey lactone derivative used in the preparation prostaglandin analogues for use as vasolidator as well as EP4 receptor agonists.

Synthesis

(-)-Corey aldehyde benzoate

39746-01-5

(-)-Corey Lactone Benzoate

39746-00-4

A 1:1 methanol:methylene chloride solution (40 mL) of (3aR,4R,5R,6aS)-5-(benzoyloxy)hexahydro-2H-cyclopenta[b]furan-2-one-4-carbaldehyde (1) (purchased from Cayman Chemical Company, Ann Arbor, MI) (3.5 g, 12.8 mmol) in a 1:1 methanol:dichloromethane solution (40 mL). After 25 min of reaction, the reaction was quenched by careful addition of saturated aqueous citric acid solution (60 mL). The mixture was extracted with ethyl acetate (3 × 40 mL) and the organic layers were combined and washed sequentially with water (2 × 80 mL) and saturated saline (2 × 80 mL). The organic layer was dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give the target compound 2 (2.43 g, 69% yield).

References

[1] Patent: US6353000, 2002, B1. Location in patent: Page column 10
[2] Journal of Pharmacology and Experimental Therapeutics, 1999, vol. 290, # 3, p. 1278 - 1284
[3] Patent: US6353014, 2002, B1. Location in patent: Page column 18

(-)-Corey Lactone Benzoate synthesis

32233-40-2
39746-00-4
Synthesis of (-)-Corey Lactone Benzoate from (-)-Corey lactone diol

(-)-Corey Lactone Benzoate Preparation Products And Raw materials

Raw materials

(-)-3-OXO-6-BETA-TRITYLOXYMETHYL-7-ALPHA-BENZOYL-OXY-2-OXABICYCLO[3.3.0!OCTANE (-)-Corey aldehyde benzoate Dichloromethane Methanol Sodium borohydride

Preparation Products

(-)-Corey lactone diol (-)-3-OXO-6-BETA-TRITYLOXYMETHYL-7-ALPHA-BENZOYL-OXY-2-OXABICYCLO[3.3.0!OCTANE

(-)-Corey Lactone Benzoate Suppliers

Global( 296)Suppliers
Supplier Tel Email Country ProdList Advantage
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8615965530500 nickzhang@hangyubiotech.com China 9946 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20122 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 14014 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21586 55
Shanghai finete Pharmaceutical Co., Ltd. 		+86-18221039705 CHINA 139 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29812 58
Jinan Finer Chemical Co., Ltd 		+86-531-88989536 +86-15508631887 sales@finerchem.com China 2950 58
Henan Xiangtong Chemical Co., Ltd. 		86-371-61312303 info@hnxtchem.com CHINA 292 58
Supplier Advantage
Zibo Hangyu Biotechnology Development Co., Ltd 		58
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai finete Pharmaceutical Co., Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Jinan Finer Chemical Co., Ltd 		58
Henan Xiangtong Chemical Co., Ltd. 		58

View Lastest Price from (-)-Corey Lactone Benzoate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(-)-Corey Lactone Benzoate pictures 2026-06-23 (-)-Corey Lactone Benzoate
39746-00-4
 1g 99.0%min 10 KGS WUHAN FORTUNA CHEMICAL CO., LTD
(-)-Corey Lactone Benzoate pictures 2026-06-22 (-)-Corey Lactone Benzoate
39746-00-4
 2Kg/Bag 98% up 20 tons Sinoway Industrial co., ltd.
(-)-Corey lactone benzoate pictures 2026-06-16 (-)-Corey lactone benzoate
39746-00-4
 0.99 RongNa Biotechnology Co.,Ltd

(-)-Corey Lactone Benzoate Spectrum

(-)-Corey Lactone Benzoate(39746-00-4)1HNMR

39746-00-4((-)-Corey Lactone Benzoate)Related Search:

(-)-Corey lactone diol N-(2-CARBOXYBENZOYL)-(-)-10,2-CAMPHORSULTAM 4-Aminophenol Gibberellic acid 2H-Cyclopenta[b]furan-2-one,hexahydro-5-hydroxy-4-(hydroxymethyl)-
(1S,5R)-(-)-2-OXABICYCLO[3.3.0]OCT-6-EN-3-ONE 4-(T-BUTYLDI-ME-SIO-ME)HEXA-H-5-(T-H-PYR AN -2-YLOXY)-CYCLOPENTA(B)FURAN-2-ON, 97 (3aR,4S,5R,6aS)-4-(hydroxyMethyl)-5-(triethylsilyloxy)-hexahydro-cyclopentafuran-2-one 2H-Cyclopenta[b]furan-2-one, hexahydro-4-(hydroxymethyl)-5-[(tetrahydro-2H-pyran-2-yl)oxy]-, (3aR,4S,5R,6aS)- (-)-Corey Lactone Diol
Trelagliptin succinate (3-TRIFLUOROMETHYLPHENOXY) ACETIC ACID ETHYL ESTER (R)-4-fluoro-2-((3-methyl-2,4-dioxo-6-(piperidin-3-ylamino)-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile Travoprost Impurity 19 TrifluoroMethyl Dechloro
2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile (-)-Corey aldehyde benzoate (3-TRIFLUOROMETHYL-PHENOXY)-ACETIC ACID

1of4

5-(Benzoyloxy)hexahydro-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one(3aα,4α,5β,6aα) (-)-5-(BENZOYLOXY)HEXAHYDRO-4-(HYDROXYME)-2H-CYCLOPENTA(B)FURAN-2-ONE, 97% 5-(BENZOYLOXY) HEXAHYDRO-4-(HYDROXYMETHYL)-2H-CYCLOPENTA[B]FURAN-2-ONE BENZOYL COREY LACTONE (-)-COREY LACTONE BENZOATE 99% (-)-COREY LACTONE BENZOATE: (3AR,4S,5R,6AS)-(-)-5-(BENZOYLOXY)-HEXAHYDRO-4(-HYDROXYMETHYL)-2H-CYCLOPENTA[B]FURAN-2-ONE (-)-6-BETA-HYDROXYMETHYL-7-ALPHA-BENZOYLOXY-CIS-2-OXABICYCLO[3.3.0]OCTAN-3-ONE(COREY''S LACTONE) [3aR-(3aα,4α,5β,6aα)]-5-(Benzoyloxy)hexahydro-4-(hydroxyMethyl)-2H-cyclopenta[b]furan-2-one PGX 4 (1R)-2β-(Hydroxymethyl)-3α-(benzoyloxy)-5α-hydroxycyclopentane-1α-acetic acid 1,5-lactone (1S,5R,6S,7R)-7-Benzoyloxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one (3aβ,6aβ)-4β-(Hydroxymethyl)-5α-(benzoyloxy)hexahydro-2H-cyclopenta[b]furan-2-one (-) Corey Alcohol Benzoate (3AR,4S,5R,6AS)-(-)-5-(BENZOYLOXY)-HEXAHYDRO-4(-HYDROXYMETHYL)-2H-CYCLOPENTA[B]FURAN-2-ONE 5-(BENZOYLOXY) HEXAHYDRO-4-(HYDROXYMETHYL)-2H-CYCLOPENTA[B]FURAN-2-ONE (3AA,4A,5BETA,6AA) (-)-6-BETA-HYDROXYMETHYL-7-ALPHA-BENZOYLOXY-CIS-2-OXABICYCLO[3.3.0]OCTAN-3-ONE (-)-5-(benzoyloxy)hexahydro-4-(hydroxyme)-2H-cycl [3aR-(3aalpha,4alpha,5beta,6aalpha)]-hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl benzoate (-)-Corey Lactone Benzoate Basic information 2H-Cyclopenta[b]furan-2-one, 5-(benzoyloxy)hexahydro-4-(hydroxymethyl)-, (3aR,4S,5R,6aS)- COREY'S LACTONE benzoic acid [4-(hydroxymethyl)-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] ester lactone benzoate (-)-Corey Lactone Benzoate in stock Factory [(3aR,4S,5R,6aS)-4-(hydroxymethyl)-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] benzoate (-)-Corey Lactone Benzoate > Travoprost Impurity 31 Travoprost Impurity 54 (-)-Corey Lactone Benzoate USP/EP/BP (-)-Corey lactone benzoate(For export only) Tafluprost Impurity 11 (Corey lactone benzoate) (-)-Corey Lactone Benzoate BCOD (-)-Corey Lactone Benzoate 39746-00-4 Iloprost Impurity 16 (-) - Benzoic acid corylilide (-) Benzoyl lactone Benzoic acid lactone (-)corey lactone benzoate (3aR,4S,5R,6aS)-4-(hydroxyMethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate BCOD 39746-00-4 39746-60-4 Latanoprost Prostaglandins