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2-Bromo-4-chloropyridine

2-Bromo-4-chloropyridine structure

CAS No.: 22918-01-0

Chemical Name:: 2-Bromo-4-chloropyridine

Synonyms: 4-CHLORO-2-BROMOPYRIDINE;2-BROMO-4-CHLOROPYRIDINE;2-broMo-4-pyridyl chloride;Pyridine, 2-bromo-4-chloro-;2-Bromo-4-chloropyridine >2-Bromo-4-chloropyridine 95%;2-broMo -4-chlorine pyridine;2-Bromo-4-chloropyridine ISO 9001：2015 REACH

CBNumber:: CB2284312

Molecular Formula:: C5H3BrClN

Molecular Weight:: 192.44

MDL Number:: MFCD03840757

MOL File:: 22918-01-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 00:05:48

Product description	Number	Pack Size	Price
2-Bromo-4-chloropyridine 95%	722413	5g	$188
2-Bromo-4-chloropyridine 95%	722413	1g	$39.6
2-Bromo-4-chloropyridine >98.0%(GC)	B4407	1g	$23
2-Bromo-4-chloropyridine >98.0%(GC)	B4407	5g	$56
2-Bromo-4-chloropyridine	FB08159	100g	$584
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2-Bromo-4-chloropyridine Properties

Melting point	<30℃
Boiling point	98°C
Density	1.736±0.06 g/cm3(Predicted)
Flash point	>110℃
storage temp.	-20°C
solubility	soluble in Methanol
pka	0.12±0.10(Predicted)
form	powder to lump to clear liquid
color	White or Colorless to Almost white or Almost colorless
InChI	InChI=1S/C5H3BrClN/c6-5-3-4(7)1-2-8-5/h1-3H
InChIKey	SURKZMFXICWLHU-UHFFFAOYSA-N
SMILES	C1(Br)=NC=CC(Cl)=C1
CAS DataBase Reference	22918-01-0(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H302-H315-H318-H335

Precautionary statements

P280-P301+P312+P330-P302+P352-P305+P351+P338+P310

target organs

Respiratory system

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-41-37/38-22

Safety Statements

26-36/37/39-39

WGK Germany

HS Code

2933399990

Storage Class

10 - Combustible liquids

Hazard Classifications

Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

2-Bromo-4-chloropyridine price More Price(76)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	722413	2-Bromo-4-chloropyridine 95%	22918-01-0	5g	$188	2026-04-30	Buy
Sigma-Aldrich	722413	2-Bromo-4-chloropyridine 95%	22918-01-0	1g	$39.6	2023-06-20	Buy
TCI Chemical	B4407	2-Bromo-4-chloropyridine >98.0%(GC)	22918-01-0	1g	$23	2026-04-30	Buy
TCI Chemical	B4407	2-Bromo-4-chloropyridine >98.0%(GC)	22918-01-0	5g	$56	2026-04-30	Buy
Biosynth	FB08159	2-Bromo-4-chloropyridine	22918-01-0	100g	$584	2026-06-04	Buy

Product number	Packaging	Price	Buy
722413	5g	$188	Buy
722413	1g	$39.6	Buy
B4407	1g	$23	Buy
B4407	5g	$56	Buy
FB08159	100g	$584	Buy

2-Bromo-4-chloropyridine Chemical Properties,Uses,Production

Chemical Properties

Light yellow liquid

Uses

2-Bromo-4-chloropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

To an aqueous solution of 48 % strength hydrobromic acid (82 rnL) at 0 0C was added 4-chloro-2-pyridinamine (8.9 g, 69.2 mmol) followed by addition of bromine (33.4 g, 209 mmol) over 10 min. The resulting mixture was cooled to -10 0C, and a solution of NaNO2 (10.65 g, 154 mmol) in H2O (20 rnL) was poured over 30 min. The mixture was warmed at room temperature and stirred overnight. The mixture was cooled to 0 0C, and NaOH (35 %) was added until the pH >10. The mixture was then extracted with ethyl acetate. The organic layer was then dried, filtered, and concentrated in vacuo. The product was purified via column chromatography (0-20 per cent ethyl acetate/hexane) to afford 2-bromo-4-chloropyridine (12.1 g, 92 %).

References

[1] Patent: WO2008/124575, 2008, A1. Location in patent: Page/Page column 110; 111
[2] Patent: WO2008/124582, 2008, A1. Location in patent: Page/Page column 92-93
[3] Patent: WO2003/99274, 2003, A1. Location in patent: Page 562-563

2-Bromo-4-chloropyridine synthesis

Synthesis of 2-Bromo-4-chloropyridine from 2-Amino-4-chloropyridine

2-Bromo-4-chloropyridine Preparation Products And Raw materials

Raw materials

4-Chloropyridine-2-carboxylic acid 4-chloropyridine Hydrogen bromide 2-Amino-4-chloropyridine Sodium nitrite

Sodium hydroxide

1of2

Preparation Products

2-Bromo-4-methoxypyridine

2-Bromo-4-chloropyridine Suppliers

Global( 300)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+86-15350571055	Sibel@chuanghaibio.com	China	8737	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20111	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	877	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	809	58
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	722	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32998	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10399	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2971	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
Chembon Pharmaceutical Co., Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Nanjing Dolon Biotechnology Co.,Ltd.	58

View Lastest Price from 2-Bromo-4-chloropyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-13	2-Chloro-4-bromopyridine 22918-01-0	$1.00-200.00	1KG	99%, 99.5% Sublimated		Henan Fengda Chemical Co., Ltd
2026-03-20	2-Bromo-4-chloropyridine 22918-01-0		1KG	99%	20 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-11-18	2-Bromo-4-chloropyridine 22918-01-0	$1.10	1g	99.00%	100 Tons min	Dideu Industries Group Limited

2-Chloro-4-bromopyridine
22918-01-0
$1.00-200.00
99%, 99.5% Sublimated
Henan Fengda Chemical Co., Ltd

2-Bromo-4-chloropyridine
22918-01-0
99%
Hebei Chuanghai Biotechnology Co., Ltd

2-Bromo-4-chloropyridine
22918-01-0
$1.10
99.00%
Dideu Industries Group Limited

2-Bromo-4-chloropyridine Spectrum

2-Bromo-4-chloropyridine(22918-01-0)¹HNMR

22918-01-0(2-Bromo-4-chloropyridine)Related Search:

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2-BROMO-4-CHLOROPYRIDINE 4-CHLORO-2-BROMOPYRIDINE 2-broMo-4-pyridyl chloride Pyridine, 2-bromo-4-chloro- 2-broMo -4-chlorine pyridine 2-Bromo-4-chloropyridine 95% 2-Bromo-4-chloropyridine > 2-Bromo-4-chloropyridine ISO 9001：2015 REACH 22918-01-0 C5H3BrCIN C5H3NBrCl Heterocycle-Pyridine series alkyl bromide| alkyl chloride Pyridines, Pyrimidines, Purines and Pteredines Halides Pyridines Pyridine Variety of halogenated heterocyclic series