2,3-DIHYDRO-1-BENZOFURAN-2-YLMETHANOL
- CAS No.
- 66158-96-1
- Chemical Name:
- 2,3-DIHYDRO-1-BENZOFURAN-2-YLMETHANOL
- Synonyms
- AKOS BB-6927;2-BenzofuranMethanol,2,3-dihydro-;2-HydroxyMethyl-2,3-dihydrobenzofuran;2,3-DIHYDRO-1-BENZOFURAN-2-YLMETHANOL;(2,3-DIHYDRO-BENZOFURAN-2-YL)-METHANOL;2,3-DIHYDRO-2-(HYDROXYMETHYL)BENZOFURAN;2-HYDROXYMETHYL-2,3-DIHYDRO-1-BENZOFURAN;2,3-Dihydro-2-(hydroxymethyl)benzo[b]furan;2,3-Dihydro-2-(hydroxymethyl)benzo[b]furan97%;2-(Hydroxymethyl)-2,3-dihydro-1-benzofuran 97%
- CBNumber:
- CB2290988
- Molecular Formula:
- C9H10O2
- Molecular Weight:
- 150.17
- MDL Number:
- MFCD03086171
- MOL File:
- 66158-96-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Hydroxymethyl-2,3-dihydrobenzofuran | H947870 | 500mg | $165 |
| (2,3-Dihydrobenzofuran-2-yl)methanol | W7718 | 1g | $186 |
| (2,3-Dihydrobenzofuran-2-yl)methanol | FD142842 | 1g | $189 |
| 2,3-Dihydro-1-benzofuran-2-ylmethanol | 027264 | 500mg | $228 |
| (2,3-Dihydrobenzofuran-2-yl)methanol | FD142842 | 250mg | $62.5 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P280 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| Hazard Note | Harmful |
| HazardClass | IRRITANT |
| HS Code | 2932990090 |
2,3-DIHYDRO-1-BENZOFURAN-2-YLMETHANOL price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | H947870 | 2-Hydroxymethyl-2,3-dihydrobenzofuran | 66158-96-1 | 500mg | $165 | 2021-12-16 | Buy |
| AK Scientific | W7718 | (2,3-Dihydrobenzofuran-2-yl)methanol | 66158-96-1 | 1g | $186 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD142842 | (2,3-Dihydrobenzofuran-2-yl)methanol | 66158-96-1 | 1g | $189 | 2021-12-16 | Buy |
| Matrix Scientific | 027264 | 2,3-Dihydro-1-benzofuran-2-ylmethanol | 66158-96-1 | 500mg | $228 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD142842 | (2,3-Dihydrobenzofuran-2-yl)methanol | 66158-96-1 | 250mg | $62.5 | 2021-12-16 | Buy |
2,3-DIHYDRO-1-BENZOFURAN-2-YLMETHANOL Chemical Properties,Uses,Production
Chemical Properties
2,3-dihydrobenzofuran-2-methanol is Colorless Oil
Uses
2-Hydroxymethyl-2,3-dihydrobenzofuran (H947870) is a reactant used in the preparation of thromboxane A2 agonist indane derivatives.
Uses
2,3-dihydrobenzofuran-2-methanol is a reactant used in the preparation of thromboxane A2 agonist indane derivatives.
Synthesis
1745-81-9
66158-96-1
2-Allylphenol (5) (200 mg, 1.49 mmol) was used as a raw material, which was mixed with m-chloroperoxybenzoic acid (616 mg, 3.57 mmol) in dichloromethane (DCM, 30 mL) and the reaction was stirred for 6 hours at room temperature. Subsequently, potassium carbonate (K2CO3, 617 mg, 4.47 mmol) and methanol (25 mL) were added to the reaction system and stirring was continued for 14 hours. After completion of the reaction, the solvent was removed by evaporation and diluted by adding water (15 mL). The mixture was extracted with dichloromethane (3 x 20 mL), the organic phases were combined, washed with brine (10 mL), dried over anhydrous sodium sulfate (Na2SO4), and the solvent was evaporated again. The crude product was purified by fast column chromatography (eluent: ethyl acetate/hexane=1:7) to afford the target compound (2,3-dihydrobenzofuran-2-yl)methanol (6) (195 mg, 87% yield) as a light yellow oil. The structure of the product was confirmed by 1H NMR (CDCl3, 300 MHz) and FTIR (neat): 1H NMR δ 7.17 (d, 1H, J = 7.4 Hz), 7.11 (t, 1H, J = 7.6 Hz), 6.85 (t, 1H, J = 7.4 Hz), 6.79 (d, 1H, J = 7.4 Hz), 4.91 (m, 1H) , 3.85 (dd, 1H, J = 12.0, 3.2 Hz), 3.74 (dd, 1H, J = 12.0, 6.3 Hz), 3.25 (dd, 1H, J = 15.5, 9.4 Hz), 3.01 (dd, 1H, J = 15.5, 7.4 Hz); FTIR 3391, 3049, 1047 cm-1.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 12, p. 2545 - 2549
[2] Advanced Synthesis and Catalysis, 2007, vol. 349, # 17-18, p. 2685 - 2689
[3] Bioorganic and medicinal chemistry letters, 1999, vol. 9, # 3, p. 401 - 406
[4] Tetrahedron Asymmetry, 2000, vol. 11, # 16, p. 3375 - 3393
[5] Synthesis (Germany), 2017, vol. 49, # 18, p. 4254 - 4260
2,3-DIHYDRO-1-BENZOFURAN-2-YLMETHANOL Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Aceschem Inc. | +1-817863-6948 +1-（817）863-6948 | sales@aceschem.com | United States | 19632 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53899 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40228 | 62 |
View Lastest Price from 2,3-DIHYDRO-1-BENZOFURAN-2-YLMETHANOL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-01-19 | 2,3-DIHYDRO-1-BENZOFURAN-2-YLMETHANOL
66158-96-1
|
US $1.00 / KG | 1KG | 99.0% | 100kg | Career Henan Chemical Co |
-
- 2,3-DIHYDRO-1-BENZOFURAN-2-YLMETHANOL
66158-96-1
- US $1.00 / KG
- 99.0%
- Career Henan Chemical Co
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