1-N-PHENYL-PIPERIDIN-4-ONE
- CAS No.
- 19125-34-9
- Chemical Name:
- 1-N-PHENYL-PIPERIDIN-4-ONE
- Synonyms
- N-Phenyl-4-piperidone;1-Phenyl-4-piperidone;N-phenylpiperidin-4-one;4-Piperidinone,1-phenyl-;1-PHENYLPIPERIDIN-4-ONE;1-N-PHENYL-PIPERIDIN-4-ONE;1-phenylpiperidin-4-one(SALTDATA: FREE)
- CBNumber:
- CB2301048
- Molecular Formula:
- C11H13NO
- Molecular Weight:
- 175.23
- MDL Number:
- MFCD07367770
- MOL File:
- 19125-34-9.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
1-N-PHENYL-PIPERIDIN-4-ONE price More Price(26)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | P336245 | 1-Phenylpiperidin-4-one | 19125-34-9 | 100mg | $120 | 2021-12-16 | Buy |
TRC | P336245 | 1-Phenylpiperidin-4-one | 19125-34-9 | 5G | $715 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0018385 | 1-N-PHENYL-PIPERIDIN-4-ONE 95.00% | 19125-34-9 | 1G | $750.68 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 66704 | 1-Phenylpiperidin-4-one | 19125-34-9 | 100mg | $610 | 2021-12-16 | Buy |
Matrix Scientific | 131962 | 1-Phenylpiperidin-4-one 97% | 19125-34-9 | 5g | $874 | 2021-12-16 | Buy |
1-N-PHENYL-PIPERIDIN-4-ONE Chemical Properties,Uses,Production
Uses
1-Phenylpiperidin-4-one is a reagent used in the preparation of isoteric N-arylpiperazine as dihydropyridine NPY1 receptor antagonists.
Synthesis
![8-phenyl-1,4-dioxa-8-azaspiro[4.5]decane](/CAS/20150408/GIF/198649-62-6.gif)
198649-62-6

19125-34-9
The compound (CAS: 198649-62-6) was dissolved in ethanol (60 mL), 2M hydrochloric acid (15 mL) was added and the reaction was heated to reflux for 5 hours. Upon completion of the reaction, the reaction solution was neutralized by adding aqueous sodium bicarbonate to the reaction solution, followed by extraction of the organic phase with ethyl acetate. The organic phase was concentrated under reduced pressure and the resulting residue was purified by silica gel column chromatography (Moritex Corporation, eluent: hexane/ethyl acetate=5/1). Fractions with an Rf value of 0.40 were collected and confirmed by thin layer chromatography and concentrated under reduced pressure to give 1-N-phenyl-1-piperidin-4-one (6.1 g, 35 mmol) as a colorless oil (quantitative yield). Mass spectrum (MS) m/z: 176 (M + H)+.
References
[1] Patent: US2011/112103, 2011, A1. Location in patent: Page/Page column 23
[2] Patent: WO2010/81851, 2010, A1. Location in patent: Page/Page column 15; 16
[3] Patent: WO2013/6408, 2013, A1. Location in patent: Page/Page column 63
[4] Tetrahedron Letters, 2007, vol. 48, # 23, p. 4097 - 4099
[5] Patent: CN105985355, 2016, A. Location in patent: Paragraph 0639; 0640; 0641; 0642
1-N-PHENYL-PIPERIDIN-4-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2176 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20342 | 58 |
changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9647 | 58 |
BTC pharm India | +918790379245 | banny.janga@btcpharm.com | India | 1262 | 58 |
View Lastest Price from 1-N-PHENYL-PIPERIDIN-4-ONE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2019-09-02 | 1-N-PHENYL-PIPERIDIN-4-ONE
19125-34-9
|
US $1.00 / KG | 1KG | 98% | 1lg; 2kg; 5kg; 10kg; 100kg | Career Henan Chemical Co |
-
- 1-N-PHENYL-PIPERIDIN-4-ONE
19125-34-9
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
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