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1-N-PHENYL-PIPERIDIN-4-ONE

CAS No.
19125-34-9
Chemical Name:
1-N-PHENYL-PIPERIDIN-4-ONE
Synonyms
N-Phenyl-4-piperidone;1-Phenyl-4-piperidone;N-phenylpiperidin-4-one;4-Piperidinone,1-phenyl-;1-PHENYLPIPERIDIN-4-ONE;1-N-PHENYL-PIPERIDIN-4-ONE;1-phenylpiperidin-4-one(SALTDATA: FREE)
CBNumber:
CB2301048
Molecular Formula:
C11H13NO
Molecular Weight:
175.23
MDL Number:
MFCD07367770
MOL File:
19125-34-9.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:49

1-N-PHENYL-PIPERIDIN-4-ONE Properties

Melting point 36.5-37.2℃
storage temp. Sealed in dry,Room Temperature
Appearance Light yellow to brown Solid
InChI InChI=1S/C11H13NO/c13-11-6-8-12(9-7-11)10-4-2-1-3-5-10/h1-5H,6-9H2
InChIKey VPGLFNOKHAIGEC-UHFFFAOYSA-N
SMILES N1(C2=CC=CC=C2)CCC(=O)CC1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P

1-N-PHENYL-PIPERIDIN-4-ONE price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P336245 1-Phenylpiperidin-4-one 19125-34-9 100mg $120 2021-12-16 Buy
TRC P336245 1-Phenylpiperidin-4-one 19125-34-9 5G $715 2021-12-16 Buy
American Custom Chemicals Corporation CHM0018385 1-N-PHENYL-PIPERIDIN-4-ONE 95.00% 19125-34-9 1G $750.68 2021-12-16 Buy
Medical Isotopes, Inc. 66704 1-Phenylpiperidin-4-one 19125-34-9 100mg $610 2021-12-16 Buy
Matrix Scientific 131962 1-Phenylpiperidin-4-one 97% 19125-34-9 5g $874 2021-12-16 Buy
Product number Packaging Price Buy
P336245 100mg $120 Buy
P336245 5G $715 Buy
CHM0018385 1G $750.68 Buy
66704 100mg $610 Buy
131962 5g $874 Buy

1-N-PHENYL-PIPERIDIN-4-ONE Chemical Properties,Uses,Production

Uses

1-Phenylpiperidin-4-one is a reagent used in the preparation of isoteric N-arylpiperazine as dihydropyridine NPY1 receptor antagonists.

Synthesis

8-phenyl-1,4-dioxa-8-azaspiro[4.5]decane

198649-62-6

1-N-PHENYL-PIPERIDIN-4-ONE

19125-34-9

The compound (CAS: 198649-62-6) was dissolved in ethanol (60 mL), 2M hydrochloric acid (15 mL) was added and the reaction was heated to reflux for 5 hours. Upon completion of the reaction, the reaction solution was neutralized by adding aqueous sodium bicarbonate to the reaction solution, followed by extraction of the organic phase with ethyl acetate. The organic phase was concentrated under reduced pressure and the resulting residue was purified by silica gel column chromatography (Moritex Corporation, eluent: hexane/ethyl acetate=5/1). Fractions with an Rf value of 0.40 were collected and confirmed by thin layer chromatography and concentrated under reduced pressure to give 1-N-phenyl-1-piperidin-4-one (6.1 g, 35 mmol) as a colorless oil (quantitative yield). Mass spectrum (MS) m/z: 176 (M + H)+.

References

[1] Patent: US2011/112103, 2011, A1. Location in patent: Page/Page column 23
[2] Patent: WO2010/81851, 2010, A1. Location in patent: Page/Page column 15; 16
[3] Patent: WO2013/6408, 2013, A1. Location in patent: Page/Page column 63
[4] Tetrahedron Letters, 2007, vol. 48, # 23, p. 4097 - 4099
[5] Patent: CN105985355, 2016, A. Location in patent: Paragraph 0639; 0640; 0641; 0642

1-N-PHENYL-PIPERIDIN-4-ONE Preparation Products And Raw materials

Global( 89)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29855 58
Changzhou Ditong Chemical Co.,Ltd
+86-0519-88299272 info@edengenechem.com China 2176 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 sales@sarms4muscle.com China 10473 58
CD Chemical Group Limited
+8615986615575 info@codchem.com China 20342 58
changzhou huayang technology co., ltd
+8615250961469 2571773637@qq.com China 9647 58
BTC pharm India
+918790379245 banny.janga@btcpharm.com India 1262 58

View Lastest Price from 1-N-PHENYL-PIPERIDIN-4-ONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-N-PHENYL-PIPERIDIN-4-ONE pictures 2019-09-02 1-N-PHENYL-PIPERIDIN-4-ONE
19125-34-9
US $1.00 / KG 1KG 98% 1lg; 2kg; 5kg; 10kg; 100kg Career Henan Chemical Co

1-N-PHENYL-PIPERIDIN-4-ONE Spectrum

1-Phenyl-4-piperidone N-Phenyl-4-piperidone 4-Piperidinone,1-phenyl- 1-N-PHENYL-PIPERIDIN-4-ONE 1-PHENYLPIPERIDIN-4-ONE 1-phenylpiperidin-4-one(SALTDATA: FREE) N-phenylpiperidin-4-one 19125-34-9 CHIRAL CHEMICALS