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Neocryptotanshinone

Neocryptotanshinone Structure
Neocryptotanshinone structure
CAS No.
109664-02-0
Chemical Name:
Neocryptotanshinone
Synonyms
Neocryptotanshinone;(R)-3-Hydroxy-2-(1-hydroxypropan-2-yl)-8,8-dimethyl-5,6,7,8-tetrahydrophenanthrene-1,4-dione;5,6,7,8-Tetrahydro-3-hydroxy-2-[(1R)-2-hydroxy-1-methylethyl]-8,8-dimethyl-1,4-phenanthrenedione;1,4-Phenanthrenedione, 5,6,7,8-tetrahydro-3-hydroxy-2-[(1R)-2-hydroxy-1-methylethyl]-8,8-dimethyl-
CBNumber:
CB23037421
Molecular Formula:
C19H22O4
Molecular Weight:
314.38
MDL Number:
MFCD32878228
MOL File:
109664-02-0.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:55
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Neocryptotanshinone Properties

Boiling point 517.1±50.0 °C(Predicted)
Density 1?+-.0.06 g/cm3(Predicted)
storage temp. 4°C, protect from light
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka 4.50±1.00(Predicted)
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Neocryptotanshinone price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0077856 Neocryptotanshinone 98.82% 109664-02-0 5mg $550 2021-12-16 Buy
ChemScene CS-0077856 Neocryptotanshinone 98.82% 109664-02-0 10mg $920 2021-12-16 Buy
Arctom CFN92181 Neocryptotanshinone ≥98% 109664-02-0 10mg $398 2021-12-16 Buy
Product number Packaging Price Buy
CS-0077856 5mg $550 Buy
CS-0077856 10mg $920 Buy
CFN92181 10mg $398 Buy

Neocryptotanshinone Chemical Properties,Uses,Production

Uses

Neocryptotanshinone, a fatty diterpenoids from Salvia Miltiorrhiza, inhibits lipopolysaccharide-induced inflammation by suppression of NF-κB and iNOS signaling pathways[1][2].

in vivo

Neocryptotanshinone causes reversals of decreased pain thresholds induced by MSU treatment after 30, 60, and 120 min S. miltiorrhiza Bunge extract treatment (contains single active components)[3].

Animal Model:MSU-induced pain model in male ICR mice (weighing 20-25 g)[2]
Dosage:10, 25, 50 or 100 mg/kg
Administration:Oral gavage; for 30, 60, 120 min
Result:Inhibited inflammatory symptoms and nociceptive behaviors in a dose-dependent manner.

IC 50

iNOS

References

[1] Chuanhong Wu, et al. Neocryptotanshinone Inhibits Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages by Suppression of NF-κB and iNOS Signaling Pathways. Acta Pharm Sin B. 2015 Jul;5(4):323-9. DOI:10.1016/j.apsb.2015.01.010
[2] H C Lin, et al. Two New Fatty Diterpenoids From Salvia Miltiorrhiza. J Nat Prod. 2001 May;64(5):648-50. DOI:10.1021/np000345v
[3] FENG Jinghui, et al. Effects of Salvia miltiorrhiza Bunge extract and its single components on monosodium urate-induced pain in vivo and lipopolysaccharide-induced inflammation in vitro. J Tradit Chin Med. 2021. 41(2): 219-226. PMID:33825401

Neocryptotanshinone synthesis

2270-59-9
109664-02-0
Synthesis of Neocryptotanshinone from 5-BROMO-2-METHYL-2-PENTENE

Neocryptotanshinone Preparation Products And Raw materials

Raw materials

2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-7-[(1R)-2-hydroxy-1-methylethyl]-1,1-dimethyl-, (4aR,9S,10aS)- 1-Naphthalenol, 5,6,7,8-tetrahydro-5,5-dimethyl- 1,2,3,4-tetrahydro-5-Methoxy-1,1-diMethylnaphthalene Cryptotanshinone 5-BROMO-2-METHYL-2-PENTENE
2-Bromoanisole Anisole

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Preparation Products

Neocryptotanshinone Suppliers

Global( 66)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897 sales@biopurify.com China 3772 58
Hubei Ipure Biology Co., Ltd 		+8613367258412 ada@ipurechemical.com China 10244 58
HONG KONG IPURE BIOLOGY CO.,LIMITED 		86 18062405514 18062405514 ada@ipurechemical.com CHINA 3461 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38663 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+86-18621343501; +undefined18621343501 product@acmec-e.com China 33338 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 		+8613817748580 cooperation@kean-chem.com China 40066 58
Mensura Group Limited 		+8618109034517 1058503172@qq.com China 2900 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10523 58
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548 cwb1@biopurify.cn China 2376 60
Supplier Advantage
Chengdu Biopurify Phytochemicals Ltd. 		58
Hubei Ipure Biology Co., Ltd 		58
HONG KONG IPURE BIOLOGY CO.,LIMITED 		58
TargetMol Chemicals Inc. 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58
Aladdin Scientific 		58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 		58
Mensura Group Limited 		58
cjbscvictory 58
Chengdu Biopurify Phytochemicals Ltd. 60

View Lastest Price from Neocryptotanshinone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Neocryptotanshinone pictures 2024-10-28 Neocryptotanshinone
109664-02-0
 US $400.00 / mg 10g TargetMol Chemicals Inc.

109664-02-0(Neocryptotanshinone)Related Search:

Tanshinone IIA Salvianolic acid Salvianolicacid C 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid magnessium lithospermate B
9'''-MethyllithosperMate B 9'''-MethyllithosperMate B Sodium danshensu TanshinoneIIA 7-Ethyl-10-hydroxycamptothecin
5,6,7,8-Tetrahydro-3-hydroxy-2-isopropyl-8,8-dimethyl-1,4-phenanthrenedione 1,2-Didehydrocryptotanshinone (8S)-1,2,3,4,8,9-Hexahydro-4,4,8-trimethylphenanthro[3,2-b]furan-7,11-dione TANSHINONE ⅡA Cryptotanshinone

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Neocryptotanshinone 5,6,7,8-Tetrahydro-3-hydroxy-2-[(1R)-2-hydroxy-1-methylethyl]-8,8-dimethyl-1,4-phenanthrenedione 1,4-Phenanthrenedione, 5,6,7,8-tetrahydro-3-hydroxy-2-[(1R)-2-hydroxy-1-methylethyl]-8,8-dimethyl- (R)-3-Hydroxy-2-(1-hydroxypropan-2-yl)-8,8-dimethyl-5,6,7,8-tetrahydrophenanthrene-1,4-dione 109664-02-0