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Verbascoside

CAS No.
61276-17-3
Chemical Name:
Verbascoside
Synonyms
ACTEOSIDE;ISOVERBASCOSIDE;Acetoside;KUSAGININ;Kusagi;TJC 160;NSC 603831;Russetinol;Verbacoside;VERBASCOSIDE
CBNumber:
CB2306760
Molecular Formula:
C29H36O15
Molecular Weight:
624.59
MDL Number:
MFCD00221751
MOL File:
61276-17-3.mol
MSDS File:
SDS
Last updated:2026-01-13 11:17:02
Product description Number Pack Size Price
Verbascoside phyproof? Reference Substance PHL89289 10MG $524
Verbascoside United States Pharmacopeia (USP) Reference Standard 1711455 15mg $445
Verbascoside primary pharmaceutical reference standard 00820580 10mg $654
Verbascoside >97.0%(HPLC) V0153 10mg $120
Verbascoside >97.0%(HPLC) V0153 50mg $419
More product size

Verbascoside Properties

Melting point 232℃
Boiling point 908.8±65.0 °C(Predicted)
Density 1.60±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Ethyl Acetate (Very Slightly), Methanol (Slightly)
pka 9.31±0.10(Predicted)
form Solid
color White to Pale Yellow
Stability Hygroscopic
Major Application metabolomics
vitamins, nutraceuticals, and natural products
Cosmetics Ingredients Functions CHELATING
SKIN PROTECTING
ANTIOXIDANT
BLEACHING
InChIKey FBSKJMQYURKNSU-ZLSOWSIRSA-N
SMILES O([C@@H]1O[C@H]([C@@H]([C@H]([C@H]1O)O)O)C)[C@@H]1[C@H]([C@@H](O[C@@H]([C@H]1OC(=O)/C=C/C1C=CC(=C(C=1)O)O)CO)OCCC1C=CC(=C(C=1)O)O)O
LogP 0.077 (est)
CAS DataBase Reference 61276-17-3(CAS DataBase Reference)
FDA UNII 3TGX09BD5B
UNSPSC Code 85151701
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety Statements  24/25
WGK Germany  2
RTECS  LZ5786000
HS Code  29389090
Storage Class 11 - Combustible Solids
Toxicity LD50 oral in rat: > 5gm/kg

Verbascoside price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL89289 Verbascoside phyproof? Reference Substance 61276-17-3 10MG $524 2026-03-19 Buy
Sigma-Aldrich 1711455 Verbascoside United States Pharmacopeia (USP) Reference Standard 61276-17-3 15mg $445 2026-03-19 Buy
Sigma-Aldrich 00820580 Verbascoside primary pharmaceutical reference standard 61276-17-3 10mg $654 2026-03-19 Buy
TCI Chemical V0153 Verbascoside >97.0%(HPLC) 61276-17-3 10mg $120 2026-03-19 Buy
TCI Chemical V0153 Verbascoside >97.0%(HPLC) 61276-17-3 50mg $419 2026-03-19 Buy
Product number Packaging Price Buy
PHL89289 10MG $524 Buy
1711455 15mg $445 Buy
00820580 10mg $654 Buy
V0153 10mg $120 Buy
V0153 50mg $419 Buy

Verbascoside Chemical Properties,Uses,Production

Description

Verbascoside is isolated from Lantana camara, acts as an ATP-competitive inhibitor of PKC, with an IC50 of 25 µM, and has antitumor, anti-inflammatory and antineuropathic pain activity.

Natural occurrences

Verbascoside can be found in species in all the families of the order Lamiales (syn. Scrophulariales). Only two examples are known from outside the order,in the clade Asterids.

Mechanism of action

It is known, that amyloid fibrils accumulation in cerebral can easily lead to neurodegenerative disorders. Acteoside has been reported to inhibit Aβ42 aggregation by activating nuclear translocation of the transcription factor NF-E2-related factor 2 (Nrf2), increasing heme oxygenase-1 (HO-1) expression. It has also been shown that acteoside could decrease nitric oxide synthase (NOS) activity and caspase-3 expression.

Chemical Properties

White solid

Uses

Verbascoside is an agent producing effects on anti-GBM nephritis in rats. Effective agent against glomerulonephritis. Phenolic anti-oxidant agent.

Definition

ChEBI: Acteoside is a glycoside that is the alpha-L-rhamnosyl-(1->3)-beta-D-glucoside of hydroxytyrosol in which the hydroxy group at position 4 of the glucopyranosyl moiety has undergone esterification by formal condensation with trans-caffeic acid. It has a role as a neuroprotective agent, an antileishmanial agent, an anti-inflammatory agent, a plant metabolite and an antibacterial agent. It is a cinnamate ester, a disaccharide derivative, a member of catechols, a polyphenol and a glycoside. It is functionally related to a hydroxytyrosol and a trans-caffeic acid.

Biological Activity

Verbascoside has anti-inflammatory and photoprotective properties. It has shown neuroprotective effects on PC12 neuronal cells against neurotoxicity. Verbascoside is proven to be a potent inhibitor of xanthine oxidase (XOD) in in vitro studies.', 'Phenylethanoid glycoside. Antioxidant and antiproliferative.

Synthesis

Method of extracting ergosterol from cinnamon flower, comprising the steps of: S1. grinding osmanthus flowers into powder; S2. extracting with a cord extractor; S3. extracting and concentrating the crude extract of cinnamon obtained from step S2, preferably, successively extracting and concentrating the crude extract of cinnamon with petroleum ether, ethyl acetate, and n-butanol saturated with water; S5. spinning and evaporating at 40 C., and then lyophilizing, which is to obtain ergosterol. HPLC determination of concentrated cinnamon crude extract: the preparation of cinnamon crude extract solution: precision weighing of cinnamon crude extract 2mg, placed in a 25mL measuring flask, add the appropriate amount of methanol dissolved and fixed, filtered through a 0.45m filter membrane, cinnamon crude extract solution solution.

Enzyme inhibitor

This plant glycoside and antioxidant (FW = 624.60 g/mol; CAS 61276-173), also known as verbascoside, inhibits TNFa-mediated apoptosis in LPSstimulated macrophages as well as 1-methyl-4-phenylpyridiniuminduced apoptosis in cerebellar granule neurons. It also inhibits proliferation of human promyelocytic HL-60 leukemia cells by inducing cell cycle arrest at the G0/G1 phase, followed by differentiation into monocytes. Acteoside inhibits PMA-induced invasion and migration of human fibrosarcoma cells by Ca2+-dependent CaMK/ERK and JNK/NFκB-signaling pathways. Acteoside thus shows the potential as antimetastatic agent. Another intriguing finding is that acteoside inhibits amyloid-β aggregation. Target(s): aldose reductase; protein kinase C; integrase, HIV-1; peptidyl-dipeptidase A, or angiotensin-converting enzyme; tyrosinase, or monophenol monooxygenase; 5-lipoxygenase, or arachidonate 5-lipoxygenase.

Verbascoside Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 384)Suppliers
Supplier Tel Email Country ProdList Advantage
BINBO BIOLOGICAL CO.,LTD
+8618629063126 info@binbobiological.com China 477 58
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883 niki@zlchemi.com China 7245 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21592 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897 sales@biopurify.com China 3751 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 52513593@qq.com CHINA 2972 58
NanJing Spring & Autumn Biological Engineering CO., LTD.
+8613815430202 sale02@cqherb.com CHINA 376 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58

View Lastest Price from Verbascoside manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cistanche Deserticola Extract Acteoside; Verbascoside; Kusaginin pictures 2026-04-21 Cistanche Deserticola Extract Acteoside; Verbascoside; Kusaginin
61276-17-3
US $0.00-0.00 / kg 1kg 1-98% 1000kg Changsha Staherb Natural Ingredients Co., Ltd.
Cistanche Deserticola Extract Acteoside; Verbascoside; Kusaginin pictures 2026-04-21 Cistanche Deserticola Extract Acteoside; Verbascoside; Kusaginin
61276-17-3
US $0.00-0.00 / kg 1kg 1-98% 1000kg Changsha Staherb Natural Ingredients Co., Ltd.
Desertliving Cistanche Extract pictures 2026-04-14 Desertliving Cistanche Extract
61276-17-3
US $0.00 / Kg/Bag 2Kg/Bag Echinacoside 80% 20 tons Sinoway Industrial co., ltd.

Verbascoside Spectrum

glucopyranoside,2-(3,4-dihydroxyphenyl)ethyl3-o-(6-deoxy-alpha-l-mannopyranos ACTEOSIDE :B-D-GLUCOPYRANOSIDE, 2-(3,4-DIHYDROXYPHENYL)ETHYL 3-O-(6-DEOXY-A-L-MANNOPYRANOSYL)-,4-[3-(3,4-DIHYDROXYPHENYL)-2-PROPENOATE],(E)-, Acetoside Extract from Verbena minutiflora (B864379) [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate VERBASCOSIDE WITH HPLC 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside 4-[(E)-3-(3,4-dihydroxyphenyl)propenoate] 3,4-Dihydroxyphenethyl alcohol acteoside Verbacoside Acteoside(Verbascoside) Distinctive PhytosteM Lilac Verbascoside ,98% NSC 603831 Russetinol StereosperMin TJC 160 Verbascoside(Acteoside) Verbascoside, froM Cistanche deserticola Y.C.Ma VERBASCOSIDE ISOVERBASCOSIDE KUSAGININ B-D-GLUCOPYRANOSIDE, 2-(3,4-DIHYDROXYPHENYL)ETHYL 3-O-(6-DEOXY-ALPHA-L-MANNOPYRANOSYL)-,4-[3-(3,4-DIHYDROXYPHENYL)-2-PROPENOATE],(E)- 4-(3-(3,4-dihydroxyphenyl)-2-propenoate),(e)-beta-d-yl) Verbascoside [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate ACTEOSIDE β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate] Nano Liposomal Acteoside Verbascoside, 98%, from Cistanche deserticola Y.C.Ma Acteoside Kusaginin 61276-17-3 Kusagi Acteoside Standard 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-Deoxy-alpha-L-mannopyranosyl)-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-beta-D-glucopyranoside Verbascoside USP/EP/BP Cistanche Deserticola Extract Acteoside (2R,3R,4R,5R,6R)-6-(3,4-Dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl (E)-3-(3,4-dihydroxyphenyl)acrylate Verbascoside (15 mg) Verbascoside, 10 mM in DMSO Verbascoside 98% Extractum Verbascum thapsi Mao Rui Glucoside 61276-17-3 reference standards from Chinese medicinal herbs (TCM). standardized herbal extract chemical reagent pharmaceutical intermediate phytochemical Miscellaneous Natural Products