6-Aminoindanone
- CAS No.
- 69975-65-1
- Chemical Name:
- 6-Aminoindanone
- Synonyms
- 6-Amino-2,3-dihydro-1H-inden-1-one;6-AMINOINDANONE;6-amino-1-indone;6-Aminoindan-1-on;6-AMINO-1-INDANONE;6-Amino-1-indenone;6-AMINO-INDAN-1-ONE;6-AMino-1-oxoindane;Disulfiram Impurity 13(Ethiolate);1H-Inden-1-one, 6-amino-2,3-dihydro-
- CBNumber:
- CB2309226
- Molecular Formula:
- C9H9NO
- Molecular Weight:
- 147.17
- MDL Number:
- MFCD00100747
- MOL File:
- 69975-65-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 6-Aminoindan-1-one 95% | AS3173 | 1g | $35 |
| 6-Aminoindan-1-one 95% | AS3173 | 5g | $154 |
| 6-Aminoindan-1-one 95% | AS3173 | 25g | $534 |
| 6-Amino-1-indanone | 054196 | 5.00g | $124 |
| 6-Amino-1-indanone | 054196 | 10.00g | $229 |
| Melting point | 167-171 °C(Solv: methanol (67-56-1)) |
|---|---|
| Boiling point | 330.3±31.0 °C(Predicted) |
| Density | 1.254±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | Solution |
| pka | 3.85±0.20(Predicted) |
| color | Light brown to black |
| InChI | InChI=1S/C9H9NO/c10-7-3-1-6-2-4-9(11)8(6)5-7/h1,3,5H,2,4,10H2 |
| InChIKey | UOJCPAAEKXNPQT-UHFFFAOYSA-N |
| SMILES | C1(=O)C2=C(C=CC(N)=C2)CC1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H310+H330-H301-H315-H319-H227 |
| Precautionary statements | P501-P260-P270-P262-P210-P271-P264-P280-P284-P370+P378-P337+P313-P305+P351+P338-P361+P364-P332+P313-P301+P310+P330-P302+P352+P310-P304+P340+P310-P403+P233-P403+P235-P405 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | 2811 |
| HazardClass | IRRITANT |
| PackingGroup | Ⅲ |
| HS Code | 29223900 |
6-Aminoindanone price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS3173 | 6-Aminoindan-1-one 95% | 69975-65-1 | 1g | $35 | 2026-06-04 | Buy |
| Activate Scientific | AS3173 | 6-Aminoindan-1-one 95% | 69975-65-1 | 5g | $154 | 2026-06-04 | Buy |
| Activate Scientific | AS3173 | 6-Aminoindan-1-one 95% | 69975-65-1 | 25g | $534 | 2026-06-04 | Buy |
| Matrix Scientific | 054196 | 6-Amino-1-indanone | 69975-65-1 | 5.00g | $124 | 2026-05-18 | Buy |
| Matrix Scientific | 054196 | 6-Amino-1-indanone | 69975-65-1 | 10.00g | $229 | 2026-05-18 | Buy |
6-Aminoindanone Chemical Properties,Uses,Production
Uses
6-Amino-1-indanone is a synthetic compound belonging to the indanone class. It is an ethylene oxide synthesized via a multi-step process involving the dehydration and reductive amination of an amine. In organic chemistry, it is used as an intermediate in the synthesis of various other compounds, such as serotonin. This compound exhibits an affinity for palladium catalysts during reductive amination, which can be used for sequence optimization experiments.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 46, p. 399, 2003 DOI: 10.1021/jm020067s
Synthesis
24623-24-3
69975-65-1
The general procedure for the synthesis of 6-amino-1-indanone from 6-nitro-1-indanone was as follows: a mixed suspension of 6-nitroindan-1-one (10 g, 56 mmol) with 10% Pd/C catalyst (2.0 g) in methanol (200 mL) was subjected to stirring in a hydrogenation reactor for 3 hr at room temperature under a hydrogen pressure of 30 psi. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to afford 6-aminoindan-1-one (7.2 g, 87% yield).
References
[1] Chemistry - A European Journal, 2015, vol. 21, # 37, p. 13052 - 13057
[2] Patent: WO2006/71940, 2006, A2. Location in patent: Page/Page column 396
[3] Patent: WO2007/148808, 2007, A1. Location in patent: Page/Page column 126-127
[4] Journal of Medicinal Chemistry, 2003, vol. 46, # 3, p. 399 - 408
[5] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 20, p. 5665 - 5670
6-Aminoindanone Preparation Products And Raw materials
Raw materials
Preparation Products
6-Aminoindanone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17339 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49859 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | sales1@artkmedchem.com | China | 39007 | 58 |
| Chongqing jooe co., ltd | +86-15223382610 | info@jooe.com | China | 15967 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| ROSEWA HOLDING GROUP CO.,LIMITED | +86-023-62871537 | sales@rosewachem.com | China | 2812 | 58 |
| Mainchem Co., Ltd. | -- | sarah@mainchem.com | China | 6528 | 58 |
