1-(3-mercapto-1-oxopropoxy)-2,5-pyrrolidinedione
- CAS No.
- 117235-10-6
- Chemical Name:
- 1-(3-mercapto-1-oxopropoxy)-2,5-pyrrolidinedione
- Synonyms
- 2,5-Dioxopyrrolidin-1-yl 3-mercaptopropanoate;RMA-445;3-Mercaptopropanyl-NHS ester;3-Mercaptopropionic acid NHS ester;Methanesulfonamide,N-(6-aminophenyl)-;3-Mercaptopropanyl-N-hydroxysuccinimide ester;3-Mercapropropanoyl-N-hydroxysuccinimide ester;(2,5-dioxopyrrolidin-1-yl) 3-sulfanylpropanoate;1-(3-mercapto-1-oxopropoxy)-2,5-pyrrolidinedione;3-Mercaptopropanyl-N-hydroxysuccinimide ester >97%
- CBNumber:
- CB23101575
- Molecular Formula:
- C7H9NO4S
- Molecular Weight:
- 203.22
- MDL Number:
- MFCD28964889
- MOL File:
- 117235-10-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 318.4±44.0 °C(Predicted) |
|---|---|
| Density | 1.40±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 9.42±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
| InChI | 1S/C7H9NO4S/c9-5-1-2-6(10)8(5)12-7(11)3-4-13/h13H,1-4H2 |
| InChIKey | UTBOEPMMEANMPS-UHFFFAOYSA-N |
| SMILES | SCCC(ON1C(CCC1=O)=O)=O |
| UNSPSC Code | 12352005 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|---|---|
| Signal word | Warning |
| Hazard statements | H226 |
| Precautionary statements | P210-P233-P303+P361+P353-P370+P378-P403+P235-P501 |
| WGK Germany | WGK 3 |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Flam. Liq. 3 |
1-(3-mercapto-1-oxopropoxy)-2,5-pyrrolidinedione price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 901699 | 3-Mercaptopropanyl-N-hydroxysuccinimide ester >95% | 117235-10-6 | 1G | $95.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | 901699 | 3-Mercaptopropanyl-N-hydroxysuccinimide ester >95% | 117235-10-6 | 5G | $403 | 2026-04-30 | Buy |
| Usbiological | 288345 | 2,5-Pyrrolidinedione, 1-(3-mercapto-1-oxopropoxy)- Asreported | 117235-10-6 | 5g | $3993 | 2026-06-03 | Buy |
| ChemScene | CS-0120080 | 3-Mercaptopropionic acid NHS ester ≥95% | 117235-10-6 | 100mg | $34 | 2026-06-04 | Buy |
| ChemScene | CS-0120080 | 3-Mercaptopropionic acid NHS ester ≥95% | 117235-10-6 | 250mg | $59 | 2026-06-04 | Buy |
1-(3-mercapto-1-oxopropoxy)-2,5-pyrrolidinedione Chemical Properties,Uses,Production
Uses
3-Mercaptopropanyl-N-hydroxysuccinimide ester is an aliphatic, heterobifunctional crosslinking reagent. Due to the functional groups, this material can be used in a multitude of applications, such as the synthesis of protien-polymer conjugates and the synthesis of functionalized quantum dots. In addition to use as a crosslinking agent, this material can also be used to install functional groups post-polymerization. The terminal N-hydroxysuccinimide (NHS) ester can react with amines while the terminal thiol can react with thiols, alkenes, and alkynes. The free thiol can also be used to form self-assembled monolayers (SAMs) on gold surfaces.
reaction suitability
reagent type: linker
IC 50
Alkyl/ether
1-(3-mercapto-1-oxopropoxy)-2,5-pyrrolidinedione Preparation Products And Raw materials
Raw materials
Preparation Products
1-(3-mercapto-1-oxopropoxy)-2,5-pyrrolidinedione Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Finetech Industry Limited | 027-87465837 19945049750 | sales@finetechnology-ind.com | China | 9331 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| DebyeTec.com Inc. | 18086626237 18086626237 | 2693528373@qq.com | China | 2937 | 56 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9796 | 55 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
| Shanghai Han-Xiang Chemical Co., Ltd. | 17754423994 | candy@biochempartner.com | China | 3057 | 58 |
| Beijing Minruida Technology Co., Ltd. | 010-82387566 | sales@mreda.com.cn | China | 19323 | 58 |
