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Crocin

Crocin Structure
Crocin structure
CAS No.
42553-65-1
Chemical Name:
Crocin
Synonyms
GARDENIN;Crocins;Crocin A;Crocin 1;saffron(natural);CROCETIN DIGENTIOBIOSYL ESTER;CROCIN;CrocinⅠ;Crocin-Ⅰ;α-Crocin
CBNumber:
CB2311935
Molecular Formula:
C44H64O24
Molecular Weight:
976.97
MDL Number:
MFCD00017495
MOL File:
42553-65-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
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Crocin Properties

Melting point 186° (effervescence)
Boiling point 1169.0±65.0 °C(Predicted)
Density 1.54±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly, Heated), Methanol (Very Slightly, Sonicated)
form Powder
pka 12.20±0.70(Predicted)
color Orange to Very Dark Purple
Merck 14,2589
Stability Light Sensitive
Major Application diagnostic assay manufacturing
hematology
histology
Cosmetics Ingredients Functions ANTIOXIDANT
COLORANT
InChIKey OXNHRKGZZFWUQZ-QORFUXSJSA-N
LogP -4.742 (est)
CAS DataBase Reference 42553-65-1
EWG's Food Scores 1
FDA UNII 877GWI46C2
UNSPSC Code 41116121
NACRES NA.47

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety Statements  24/25
WGK Germany  3
RTECS  HL7380000
F  1-8-10
HS Code  32129000
Storage Class 11 - Combustible Solids
Hazardous Substances Data 42553-65-1(Hazardous Substances Data)

Crocin price More Price(74)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 17304 Crocin for microscopy 42553-65-1 1g $64.3 2026-04-30 Buy
Sigma-Aldrich PHL80391 Crocin phyproof? Reference Substance 10MG $214 2026-04-30 Buy
Sigma-Aldrich 17304 Crocin for microscopy 42553-65-1 5g $205 2026-04-30 Buy
TCI Chemical C1527 Crocin (Gardenia Fruits Extract) 42553-65-1 25g $184 2026-04-30 Buy
Cayman Chemical 26337 Crocin/Gardenia Extract 42553-65-1 500mg $36 2026-04-30 Buy
Product number Packaging Price Buy
17304 1g $64.3 Buy
PHL80391 10MG $214 Buy
17304 5g $205 Buy
C1527 25g $184 Buy
26337 500mg $36 Buy

Crocin Chemical Properties,Uses,Production

Introduction

Crocin (crocin) is also known as a-crocin and crocetin. It is a series of ester glycosides combining water-soluble carotenoids crocetin and different sugars. It is one of the main active ingredients of saffron, including crocin -1, crocin -2, crocin -3, crocin-4 and crocetin.It is centrally acting antihypertensive and can prevent atherosclerosis and be of antithrombosis, antiplatelet aggregation, and anti myocardial ischemia.
crocin structure
crocin source

Efficacy and effect

The traditional medicine believes that the stigma croci can dredge and activate the collaterals, remove blood stasis, eradicate depression and relieve swelling and pain. It is mainly used for the treatment of anxiety depression, chest distention, irregular menstruation, postpartum haemorrhage and traumatic injury. The main effective components are crocetin and crocin, which has many pharmacological activities, such as being anti-inflammatory and analgesic, antitumor, antidepressant, hypoglycemic and lowering blood pressure. Because the water solution of stigma croci is bright yellow with sweet smell, it is often used as a food additive and high-grade edible pigment, but also can be used as high dye for silk, cotton and wool products. In recent years, pharmacological researches indicate that stigma croci has good control effect for a variety of diseases, including cancer, coronary heart disease, atherosclerosis and hyperlipidemia.

Pharmacological effects

Crocin has the effect of the anti-inflammation and treatment of soft tissue injury, gall liver protection, anti-tumor and other pharmacological effects. It is widely used in food, medicine, chemical industry and other industries. It is used in the treatment of patients with cardiovascular disease and fatty liver.with good medicinal value.

Description

Crocin/Gardenia Extract is a Gardenia extract that contains crocin I, II, and III, and crocetin, among other compounds.

Chemical Properties

Crocin is a reddish brown needle-like crystal. Slightly odor. Easily soluble in hot water, becomes the orange solution. Slightly soluble in anhydrous ethanol, ether, and other organic solvents. Insoluble in oil. The aqueous solution is weakly acidic or neutral transparent bright yellow, with a maximum absorption wavelength of 442nm. color is almost unaffected by pH value. Light and heat resistance is good in neutral or alkaline, and poor in acidic. Metal ion resistance (except iron, blackened by iron) is good. The coloring of protein is better than that of starch and is not affected by pH (pH4-10).

Uses

Crocin, is a natural carotenoid derived the flowers crocus and gardenia. Crocin has been shown to be a potent antioxidant. It has also been shown to have an antiproliferative action against cancer cells in vitro, and also possessing possible antidepressant properties.

Definition

ChEBI: Crocin-1 is a diester that is crocetin in which both of the carboxy groups have been converted to their gentiobiosyl esters. It is one of the water-soluble yellow-red pigments of saffron and is used as a spice for flavouring and colouring food. Note that in India, the term 'Crocin' is also used by GlaxoSmithKline as a brand-name for paracetamol. It has a role as an antioxidant, a food colouring, a plant metabolite and a histological dye. It is a diester, a disaccharide derivative and a diterpenoid. It is functionally related to a beta-D-gentiobiosyl crocetin and a gentiobiose.

General Description

Crocin (CR) is a water-soluble carotenoid found in Gardenia jasmi-noides Ellis and Crocus sativus (saffron). It has two D-gentiobioside glycosyl esters in its structure. CR is one of the major bioactive compounds of saffron contributing to its red color. A highly unsaturared diterpene dicarboxylic acid ester found in saffron.

Biochem/physiol Actions

Crocin alleviates some ethanol-induced impairments of learning and prevents ethanol-induced inhibition of hippocampal long-term potentiation (LTP), a form of activity-dependent synaptic plasticity that may underly learning and memory. Related CNS effects are specific to the digentiobiose ester; crocetin glucose gentiobiose ester is half as potent, and the diglucose ester has no effect at all.

Crocin Preparation Products And Raw materials

Raw materials

Ethanol Pectin COREOPSISYELLOWEXTRACT

Preparation Products

Crocin Suppliers

Global( 403)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Nakeli Biotechnology Co., Ltd. 028-61983833 19138982515 3265827856@qq.com China 1584 58
Xi'an Lyna Bio-Tech Co., Ltd. 13193362370 mia@lynabio.com China 741 55
Chengdu Biopurify Ltd. 82633860 18982077548 cwb1@biopurify.cn China 4630 58
Xi'an Hongtaiyuan Biotechnology Co., Ltd 15829065593; 15829065593 hty15829065593@qq.com China 168 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Supplier Advantage
Chengdu Nakeli Biotechnology Co., Ltd. 58
Xi'an Lyna Bio-Tech Co., Ltd. 55
Chengdu Biopurify Ltd. 58
Xi'an Hongtaiyuan Biotechnology Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Chembest Research Laboratories Limited 61
TCI (Shanghai) Development Co., Ltd. 81
Beijing HwrkChemical Technology Co., Ltd 55
Energy Chemical 61

Related articles

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  • Crocin is a carotenoid chemical compound that is present in the flowers crocus and gardenia. This is the chemical mainly respo....
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View Lastest Price from Crocin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Crocin pictures 2026-09-13 Crocin
42553-65-1
 $10.00 1ASSAYS 99% 1 ton RongNa Biotechnology Co.,Ltd
Crocin; Saffron Extract; Gardenia Extract pictures 2026-09-11 Crocin; Saffron Extract; Gardenia Extract
42553-65-1
 1KG 40%-99% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
Crocin pictures 2026-08-25 Crocin
42553-65-1
 1kg 0.99 1000kg Shaanxi Xianhe Biotech Co., Ltd
  • Crocin pictures
  • Crocin
    42553-65-1
  • $10.00
  • 99%
  • RongNa Biotechnology Co.,Ltd
  • Crocin pictures
  • Crocin
    42553-65-1
  • $0.00
  • 0.99
  • Shaanxi Xianhe Biotech Co., Ltd

Crocin Spectrum

CROCIN(42553-65-1)1HNMR

42553-65-1(Crocin)Related Search:

Croci Stigma Crocin 2 4-HYDROXYBUTYL METHACRYLATE Diethylene glycol monobutyl ether N-HEXYL ACRYLATE
PROPYL-CROTONATE 4-Hydroxybutyl acrylate Sorbic acid Butyl methacrylate trans,trans-2,4-Heptadienal
FEMA 3354 Ethyl sorbate 2,3-Dihydroxypropyl acrylate Butyl-beta-D-glucopyranoside 2-Hydroxypropyl acrylate
3-Allyloxy-1,2-propanediol 2,6-Dimethyl-2,4,6-octatriene 2,3-Dihydroxypropyl methacrylate

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ucopyranosyl)ester Crocin ,98% CrocinⅡ ,98% Crocin ,96% Crocin,Crocetin digentiobiose ester Crocetin digentiobioside Crocin A (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-Tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioic acid bis(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl) ester 8,8'-Diapo-ψ,ψ-carotene-8,8'-dioic acid bis(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl) ester 8,8'-Diapo-ψ,ψ-carotene-8,8'-dioic acid bis[6-O-β-D-glucopyranosyl-β-D-glucopyranosyl] ester trans-Crocetin di(β-D-gentiobiosyl) ester Crocin, froM Crocus sativus Crocin for microscopy Saffron, HARLECO? Crocin Crocetin digentibiose ester Crocin - microscopy grade b-D-Glucopyranose, 6-O-b-D-glucopyranosyl-,1,1'-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate Crocin/Gardenia Extract Crocin (gardenia fruit bis(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl) 8,8'-diapo-psi,psi-carotenedioate CROCIN:B-D-GLUCOPYRANOSE, 6-O--D-GLUCOPYRANOSYL-, 1,1'-[(ALL-E)-2,6,11,15-TETRAMETHYL-2,4,6,8,10,12,14-HEXADECAHEPTAENEDIOATE], crocetin digentibiose ester bis[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl] (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioate CROCIN(CRUDE)(RG) Crocin (Gardenia Fruits Extract) β-D-Glucopyranose, 6-O-β-D-glucopyranosyl-,1,1'-[(all-E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate] Crocetin digentibiose ester, Crocin BETA-D-GLUCOPYRANOSE, 6-O-BETA-D-GLUCOPYRANOSYL-, 1,1'-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-TETRAMETHYL-2,4,6,8,10,12,14-HEXADECAHEPTAENEDIOATE] B-D-GLUCOPYRANOSE, 6-O-BETA-D-GLUCOPYRANOSYL-, 1,1'-[(ALL-E)-2,6,11,15-TETRAMETHYL-2,4,6,8,10,12,14-HEXADECAHEPTAENEDIOATE] CROCETIN BIS(GENTIOBIOSYL) ESTER CROCETIN DIGENTIOBIOSYL ESTER CROCIN CROCIN GARDENIA FRUIT EXTRACT Crocin-Ⅰ ALPHA-CROCIN 8,8’-Diapo-4,4-carotenedioicacidbis(6-O-D-glucopyranosyl-D-glucopyranosyl)ester 8,8’-diapo-psi,psi-carotenedioicacid,bis(6-o-beta-d-glucopyranosyl-beta-d-gl Di-gentiobiose ester Crocin, from gardenia fruits β-D-Glucopyranose, 6-O-β-D-glucopyranosyl-, 1,1'-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate] (2E,4E,6E,8E,10E,12E,14E)-Bis((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl) 2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioate CROCIN USP/EP/BP α-Crocin CROCIN 42553-65-1 CCRIS 7705 Crocin (Gardenia Fruits Extract)（42553651）,Crocin (Gardenia Fruits Extract)（42553 65 1） Endogenous Metabolite,Crocin I,Crocin,inhibit,Inhibitor Tibetan bonus T Crocin(AS) β-D-Glucopyranose, 6-O-β-D-glucopyranosyl-, 1,1′-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate] CrocinⅠ saffron(natural) Crocin (Standard) Crocin 1 Crocins GARDENIN 42553-65-1 C44H64O24