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Crocin

Crocin Structure
Crocin structure
CAS No.
42553-65-1
Chemical Name:
Crocin
Synonyms
GARDENIN;Crocin A;Crocins;Crocin 1;saffron(natural);CROCETIN DIGENTIOBIOSYL ESTER;CROCIN;CrocinⅠ;Crocin-Ⅰ;α-Crocin
CBNumber:
CB2311935
Molecular Formula:
C44H64O24
Molecular Weight:
976.97
MDL Number:
MFCD00017495
MOL File:
42553-65-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 19:39:08
Product description Number Pack Size Price
Crocin for microscopy 17304 1g $64.3
Crocin phyproof? Reference Substance PHL80391 10MG $214
Crocin for microscopy 17304 5g $205
Crocin (Gardenia Fruits Extract) C1527 25g $184
Crocin/Gardenia Extract 26337 500mg $36
More product size
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Crocin Properties

Melting point 186° (effervescence)
Boiling point 1169.0±65.0 °C(Predicted)
Density 1.54±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly, Heated), Methanol (Very Slightly, Sonicated)
pka 12.20±0.70(Predicted)
form Powder
color Orange to Very Dark Purple
Merck 14,2589
Stability Light Sensitive
Major Application diagnostic assay manufacturing
hematology
histology
Cosmetics Ingredients Functions ANTIOXIDANT
COLORANT
InChIKey OXNHRKGZZFWUQZ-QORFUXSJSA-N
LogP -4.742 (est)
CAS DataBase Reference 42553-65-1
EWG's Food Scores 1
FDA UNII 877GWI46C2
UNSPSC Code 41116121
NACRES NA.47

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety Statements  24/25
WGK Germany  3
RTECS  HL7380000
F  1-8-10
HS Code  32129000
Storage Class 11 - Combustible Solids
Hazardous Substances Data 42553-65-1(Hazardous Substances Data)

Crocin price More Price(65)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 17304 Crocin for microscopy 42553-65-1 1g $64.3 2026-04-30 Buy
Sigma-Aldrich PHL80391 Crocin phyproof? Reference Substance 10MG $214 2026-04-30 Buy
Sigma-Aldrich 17304 Crocin for microscopy 42553-65-1 5g $205 2026-04-30 Buy
TCI Chemical C1527 Crocin (Gardenia Fruits Extract) 42553-65-1 25g $184 2026-04-30 Buy
Cayman Chemical 26337 Crocin/Gardenia Extract 42553-65-1 500mg $36 2026-04-30 Buy
Product number Packaging Price Buy
17304 1g $64.3 Buy
PHL80391 10MG $214 Buy
17304 5g $205 Buy
C1527 25g $184 Buy
26337 500mg $36 Buy

Crocin Chemical Properties,Uses,Production

Introduction

Crocin (crocin) is also known as a-crocin and crocetin. It is a series of ester glycosides combining water-soluble carotenoids crocetin and different sugars. It is one of the main active ingredients of saffron, including crocin -1, crocin -2, crocin -3, crocin-4 and crocetin.It is centrally acting antihypertensive and can prevent atherosclerosis and be of antithrombosis, antiplatelet aggregation, and anti myocardial ischemia.
crocin structure
crocin source

Efficacy and effect

The traditional medicine believes that the stigma croci can dredge and activate the collaterals, remove blood stasis, eradicate depression and relieve swelling and pain. It is mainly used for the treatment of anxiety depression, chest distention, irregular menstruation, postpartum haemorrhage and traumatic injury. The main effective components are crocetin and crocin, which has many pharmacological activities, such as being anti-inflammatory and analgesic, antitumor, antidepressant, hypoglycemic and lowering blood pressure. Because the water solution of stigma croci is bright yellow with sweet smell, it is often used as a food additive and high-grade edible pigment, but also can be used as high dye for silk, cotton and wool products. In recent years, pharmacological researches indicate that stigma croci has good control effect for a variety of diseases, including cancer, coronary heart disease, atherosclerosis and hyperlipidemia.

Pharmacological effects

Crocin has the effect of the anti-inflammation and treatment of soft tissue injury, gall liver protection, anti-tumor and other pharmacological effects. It is widely used in food, medicine, chemical industry and other industries. It is used in the treatment of patients with cardiovascular disease and fatty liver.with good medicinal value.

Description

Crocin/Gardenia Extract is a Gardenia extract that contains crocin I, II, and III, and crocetin, among other compounds.

Chemical Properties

Crocin is a reddish brown needle-like crystal. Slightly odor. Easily soluble in hot water, becomes the orange solution. Slightly soluble in anhydrous ethanol, ether, and other organic solvents. Insoluble in oil. The aqueous solution is weakly acidic or neutral transparent bright yellow, with a maximum absorption wavelength of 442nm. color is almost unaffected by pH value. Light and heat resistance is good in neutral or alkaline, and poor in acidic. Metal ion resistance (except iron, blackened by iron) is good. The coloring of protein is better than that of starch and is not affected by pH (pH4-10).

Uses

Crocin, is a natural carotenoid derived the flowers crocus and gardenia. Crocin has been shown to be a potent antioxidant. It has also been shown to have an antiproliferative action against cancer cells in vitro, and also possessing possible antidepressant properties.

Definition

ChEBI: Crocin-1 is a diester that is crocetin in which both of the carboxy groups have been converted to their gentiobiosyl esters. It is one of the water-soluble yellow-red pigments of saffron and is used as a spice for flavouring and colouring food. Note that in India, the term 'Crocin' is also used by GlaxoSmithKline as a brand-name for paracetamol. It has a role as an antioxidant, a food colouring, a plant metabolite and a histological dye. It is a diester, a disaccharide derivative and a diterpenoid. It is functionally related to a beta-D-gentiobiosyl crocetin and a gentiobiose.

General Description

Crocin (CR) is a water-soluble carotenoid found in Gardenia jasmi-noides Ellis and Crocus sativus (saffron). It has two D-gentiobioside glycosyl esters in its structure. CR is one of the major bioactive compounds of saffron contributing to its red color. A highly unsaturared diterpene dicarboxylic acid ester found in saffron.

Biochem/physiol Actions

Crocin alleviates some ethanol-induced impairments of learning and prevents ethanol-induced inhibition of hippocampal long-term potentiation (LTP), a form of activity-dependent synaptic plasticity that may underly learning and memory. Related CNS effects are specific to the digentiobiose ester; crocetin glucose gentiobiose ester is half as potent, and the diglucose ester has no effect at all.

Crocin Preparation Products And Raw materials

Raw materials

Ethanol Pectin COREOPSISYELLOWEXTRACT

Preparation Products

Crocin Suppliers

Global( 395)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897 sales@biopurify.com China 3751 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81139210 +86-18192627656 1059@dideu.com China 3589 58
RongNa Biotechnology Co.,Ltd 		+86-86-13583358881 +8618560316533 Brad@rongnabiotech.com China 3366 58
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 deasea125996@gmail.com China 2472 58
BINBO BIOLOGICAL CO.,LTD 		+8618629063126 info@binbobiological.com China 477 58
Shaanxi Xianhe Biotech Co., Ltd 		+86-17709210191; +8617709210191 Jerry@xhobio.com China 906 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21588 55
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
Chengdu Greenpure Biopharma CO.,Ltd 		18283602253; +8618283602253 jancyzheng@gcgreenpure.com China 954 58
Supplier Advantage
Chengdu Biopurify Phytochemicals Ltd.
58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Shaanxi Dideu Medichem Co. Ltd 		58
RongNa Biotechnology Co.,Ltd 		58
Henan Bao Enluo International TradeCo.，LTD 		58
BINBO BIOLOGICAL CO.,LTD 		58
Shaanxi Xianhe Biotech Co., Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Zheyan Biotech Co., Ltd. 		58
Chengdu Greenpure Biopharma CO.,Ltd 		58

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View Lastest Price from Crocin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Crocin pictures 2026-05-25 Crocin
42553-65-1
 US $10.00 / ASSAYS 1ASSAYS 99% 1 ton RongNa Biotechnology Co.,Ltd
Crocin; Saffron Extract; Gardenia Extract pictures 2026-05-24 Crocin; Saffron Extract; Gardenia Extract
42553-65-1
 US $0.00 / KG 1KG 40%-99% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
Crocin pictures 2026-05-22 Crocin
42553-65-1
 US $0.00 / kg 1kg 0.99 1000kg Shaanxi Xianhe Biotech Co., Ltd
  • Crocin pictures
  • Crocin
    42553-65-1
  • US $10.00 / ASSAYS
  • 99%
  • RongNa Biotechnology Co.,Ltd
  • Crocin pictures
  • Crocin
    42553-65-1
  • US $0.00 / kg
  • 0.99
  • Shaanxi Xianhe Biotech Co., Ltd

Crocin Spectrum

CROCIN(42553-65-1)1HNMR

42553-65-1(Crocin)Related Search:

Croci Stigma Crocin 2 BUTYL-BETA-D-GLUCOPYRANOSIDE 2,3-DIHYDROXYPROPYL METHACRYLATE ETHYL SORBATE
N-HEXYL ACRYLATE PROPYL-CROTONATE 4-Hydroxybutyl acrylate Sorbic acid 4-HYDROXYBUTYL METHACRYLATE
Butyl methacrylate trans,trans-2,4-Heptadienal FEMA 3354 3-ALLYLOXY-1,2-PROPANEDIOL Diethylene glycol monobutyl ether
2-HYDROXYPROPYL ACRYLATE 2,6-DIMETHYL-2,4,6-OCTATRIENE 2,3-DIHYDROXYPROPYL ACRYLATE

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ucopyranosyl)ester Crocin ,98% CrocinⅡ ,98% Crocin ,96% Crocin,Crocetin digentiobiose ester Crocetin digentiobioside Crocin 1 Crocin A (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-Tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioic acid bis(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl) ester 8,8'-Diapo-ψ,ψ-carotene-8,8'-dioic acid bis(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl) ester 8,8'-Diapo-ψ,ψ-carotene-8,8'-dioic acid bis[6-O-β-D-glucopyranosyl-β-D-glucopyranosyl] ester trans-Crocetin di(β-D-gentiobiosyl) ester Crocin, froM Crocus sativus Crocin for microscopy Saffron, HARLECO? Crocin Crocetin digentibiose ester Crocin - microscopy grade b-D-Glucopyranose, 6-O-b-D-glucopyranosyl-,1,1'-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate Crocin/Gardenia Extract Crocin (gardenia fruit bis(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl) 8,8'-diapo-psi,psi-carotenedioate CROCIN:B-D-GLUCOPYRANOSE, 6-O--D-GLUCOPYRANOSYL-, 1,1'-[(ALL-E)-2,6,11,15-TETRAMETHYL-2,4,6,8,10,12,14-HEXADECAHEPTAENEDIOATE], crocetin digentibiose ester bis[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl] (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioate CROCIN(CRUDE)(RG) Crocin (Gardenia Fruits Extract) β-D-Glucopyranose, 6-O-β-D-glucopyranosyl-,1,1'-[(all-E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate] Crocetin digentibiose ester, Crocin BETA-D-GLUCOPYRANOSE, 6-O-BETA-D-GLUCOPYRANOSYL-, 1,1'-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-TETRAMETHYL-2,4,6,8,10,12,14-HEXADECAHEPTAENEDIOATE] B-D-GLUCOPYRANOSE, 6-O-BETA-D-GLUCOPYRANOSYL-, 1,1'-[(ALL-E)-2,6,11,15-TETRAMETHYL-2,4,6,8,10,12,14-HEXADECAHEPTAENEDIOATE] CROCETIN BIS(GENTIOBIOSYL) ESTER CROCETIN DIGENTIOBIOSYL ESTER CROCIN CROCIN GARDENIA FRUIT EXTRACT Crocin-Ⅰ ALPHA-CROCIN 8,8’-Diapo-4,4-carotenedioicacidbis(6-O-D-glucopyranosyl-D-glucopyranosyl)ester 8,8’-diapo-psi,psi-carotenedioicacid,bis(6-o-beta-d-glucopyranosyl-beta-d-gl Di-gentiobiose ester Crocin, from gardenia fruits Crocins β-D-Glucopyranose, 6-O-β-D-glucopyranosyl-, 1,1'-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate] (2E,4E,6E,8E,10E,12E,14E)-Bis((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl) 2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioate CROCIN USP/EP/BP α-Crocin CROCIN 42553-65-1 CCRIS 7705 Crocin (Gardenia Fruits Extract)（42553651）,Crocin (Gardenia Fruits Extract)（42553 65 1） Endogenous Metabolite,Crocin I,Crocin,inhibit,Inhibitor Tibetan bonus T Crocin(AS) β-D-Glucopyranose, 6-O-β-D-glucopyranosyl-, 1,1′-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate] CrocinⅠ saffron(natural) GARDENIN Crocin (Standard) 42553-65-1 C44H64O24