PI4KIII beta inhibitor 1
- CAS No.
- 1881233-39-1
- Chemical Name:
- PI4KIII beta inhibitor 1
- Synonyms
- CAS:1881233-39-1;PI4KIIIbeta-IN-10;PI4KIII beta inhibitor 1;PI4KIII beta inhibitor 10;PI4KIIIbeta-IN-10, 10 mM in DMSO;N-(5-(3-(N-(4-HYDROXYPHENYL)SULFAMOYL)-4-METHOXYPHENYL)-4-METHYLTHIAZOL-2-YL)PIVALAMIDE;N-[5-[3-[(4-hydroxyphenyl)sulfamoyl]-4-methoxyphenyl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide;PI4KIIIbeta-IN-10 (N-(5-(3-(N-(4-hydroxyphenyl)sulfamoyl)-4-methoxyphenyl)-4-methylthiazol-2-yl)pivalamide);Propanamide, N-[5-[3-[[(4-hydroxyphenyl)amino]sulfonyl]-4-methoxyphenyl]-4-methyl-2-thiazolyl]-2,2-dimethyl-;inhibit,Phosphatidylinositol 4 kinases,Inhibitor,PI4 kinases,PI4K,PI4KIIIbetaIN10,PI-4KIIIbeta-IN-10,PI4KIIIbeta IN 10
- CBNumber:
- CB23122932
- Molecular Formula:
- C22H25N3O5S2
- Molecular Weight:
- 475.58
- MDL Number:
- MFCD30187514
- MOL File:
- 1881233-39-1.mol
| Product description | Number | Pack Size | Price |
| PI4KIIIbeta-IN-10 99.84% | CS-5601 | 1mg | $180 |
| PI4KIIIbeta-IN-10 99.84% | CS-5601 | 5mg | $420 |
| pi4KIIIbeta-IN-10 | 9290DU | 1mg | $441 |
| PI4KIIIbeta-IN-10 | orb611434 | 5mg | $569.5 |
| PI4KIIIbeta-IN-10 99.84% | CS-5601 | 10mg | $660 |
PI4KIII beta inhibitor 1 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-5601 | PI4KIIIbeta-IN-10 99.84% | 1881233-39-1 | 1mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-5601 | PI4KIIIbeta-IN-10 99.84% | 1881233-39-1 | 5mg | $420 | 2021-12-16 | Buy |
| AK Scientific | 9290DU | pi4KIIIbeta-IN-10 | 1881233-39-1 | 1mg | $441 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611434 | PI4KIIIbeta-IN-10 | 1881233-39-1 | 5mg | $569.5 | 2021-12-16 | Buy |
| ChemScene | CS-5601 | PI4KIIIbeta-IN-10 99.84% | 1881233-39-1 | 10mg | $660 | 2021-12-16 | Buy |
PI4KIII beta inhibitor 1 Chemical Properties,Uses,Production
Uses
PI4KIIIbeta-IN-10 is a potent PI4KIIIβ inhibitor with an IC50 of 3.6 nM.
Biological Activity
PI4KIII beta inhibitor 1 is a potent PI4KIIIβ inhibitor with IC50 of 3.6 nM.
in vitro
PI4KIII beta inhibitor 1 is a potent PI4KIIIβ inhibitor with very minor off-target inhibition of PI4KIIIβ related lipid kinases. PI4KIIIbeta-IN-10 shows weak inhibition of PI3KC2γ (IC 50 < /sub> ~1 μM), PI3Kα (~10 μM), and PI4KIIIα (~3 μM), and <20% inhibition at concentrations up to 20 μM for PI4K2α, PI4K2β, and PI3Kβ.
target
| PI4KIIIβ 3.6 nM (IC 50 ) | PI4KIIIα 3 μM (IC 50 ) | PI3Kδ 720 nM (IC 50 ) | PI3KC2γ 1 μM ( IC 50 ) | PI3Kα 10 μM (IC 50 ) | PI3Kγ 20 μM (IC < sub> 50 ) |
IC 50
PI4KIIIβ: 3.6 nM (IC50); PI4KIIIα: 3 μM (IC50); PI3Kδ: 720 nM (IC50); PI3KC2γ: 1 μM (IC50); PI3Kα: 10 μM (IC50); PI3Kγ: 20 μM (IC50)
References
[1] Rutaganira FU, et al. Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ. J Med Chem. 2016 Mar 10;59(5):1830-9. DOI:10.1021/acs.jmedchem.5b01311
PI4KIII beta inhibitor 1 Preparation Products And Raw materials
Raw materials
Preparation Products
PI4KIII beta inhibitor 1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32469 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39043 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 8496 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7778 | 56 |
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2538 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71615 | 60 |
View Lastest Price from PI4KIII beta inhibitor 1 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-02-25 | PI4KIIIbeta-IN-10
1881233-39-1
|
US $73.00-268.00 / mg | 99.85% | 10g | TargetMol Chemicals Inc. | ||
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2026-02-25 | PI4KIIIbeta-IN-10
1881233-39-1
|
US $73.00-268.00 / mg | 99.85% | 10g | TargetMol Chemicals Inc. |
-

- PI4KIIIbeta-IN-10
1881233-39-1
- US $73.00-268.00 / mg
- 99.85%
- TargetMol Chemicals Inc.
-

- PI4KIIIbeta-IN-10
1881233-39-1
- US $73.00-268.00 / mg
- 99.85%
- TargetMol Chemicals Inc.




