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1-(2-Methoxyethyl)piperazine

1-(2-Methoxyethyl)piperazine structure

CAS No.: 13484-40-7

Chemical Name:: 1-(2-Methoxyethyl)piperazine

Synonyms: gx1011-aM;RARECHEM AH CK 0124;Methoxyethylpiperazine;1-(2-METHOXYETHYL)PIPERAZINE;N-(2-Methoxyethyl)piperazine;4-(2-Methoxyethyl)piperazine;1-N- Methoxyethyl piperazine;1-(2-Methoxyethyl)piperzazine;1-(2-Methoxyethyl)piperazine>Piperazine, 1-(2-methoxyethyl)-

CBNumber:: CB2315317

Molecular Formula:: C7H16N2O

Molecular Weight:: 144.21

MDL Number:: MFCD00191214

MOL File:: 13484-40-7.mol

MSDS File:: SDS

Last updated:2026-01-13 11:17:34

Product description	Number	Pack Size	Price
1-(2-Methoxyethyl)piperazine 97%	571423	1g	$42.3
1-(2-Methoxyethyl)piperazine >98.0%(GC)(T)	M2169	1g	$79
1-(2-Methoxyethyl)piperazine >98.0%(GC)(T)	M2169	5g	$199
1-(2-Methoxyethyl)piperazine	M304298	100mg	$45
1-(2-Methoxyethyl)piperazine	M304298	1g	$75
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1-(2-Methoxyethyl)piperazine Properties

Melting point	100-101 °C
Boiling point	193-194 °C (lit.)
Density	0.970 g/mL at 25 °C (lit.)
refractive index	n20/D 1.4730(lit.)
Flash point	188 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	9.15±0.10(Predicted)
form	Liquid
color	Clear colorless to yellow
BRN	105098
InChI	1S/C7H16N2O/c1-10-7-6-9-4-2-8-3-5-9/h8H,2-7H2,1H3
InChIKey	BMEMBBFDTYHTLH-UHFFFAOYSA-N
SMILES	COCCN1CCNCC1
CAS DataBase Reference	13484-40-7(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H314-H318-H227-H315-H319

Precautionary statements

P210-P264-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501-P280-P305+P351+P338-P310-P210e-P260h-P303+P361+P353-P405-P501a

target organs

respiratory tract irritation

PPE

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Codes

C,Xi

Risk Statements

34-36/37/38

Safety Statements

26-36/37/39-45-37/39

RIDADR

UN 2735 8/PG 3

WGK Germany

10-34

Hazard Note

Irritant

HazardClass

PackingGroup

Ⅲ

HS Code

29349990

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Acute Tox. 4 Inhalation
Eye Dam. 1
Repr. 2
Skin Corr. 1B
Skin Sens. 1
STOT RE 1

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	2
3		0

1-(2-Methoxyethyl)piperazine price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	571423	1-(2-Methoxyethyl)piperazine 97%	13484-40-7	1g	$42.3	2023-01-07	Buy
TCI Chemical	M2169	1-(2-Methoxyethyl)piperazine >98.0%(GC)(T)	13484-40-7	1g	$79	2026-03-19	Buy
TCI Chemical	M2169	1-(2-Methoxyethyl)piperazine >98.0%(GC)(T)	13484-40-7	5g	$199	2026-03-19	Buy
TRC	M304298	1-(2-Methoxyethyl)piperazine	13484-40-7	100mg	$45	2021-12-16	Buy
TRC	M304298	1-(2-Methoxyethyl)piperazine	13484-40-7	1g	$75	2021-12-16	Buy

Product number	Packaging	Price	Buy
571423	1g	$42.3	Buy
M2169	1g	$79	Buy
M2169	5g	$199	Buy
M304298	100mg	$45	Buy
M304298	1g	$75	Buy

1-(2-Methoxyethyl)piperazine Chemical Properties,Uses,Production

Chemical Properties

Clear colorless to yellow liquid

Uses

Reactant for:• ;Preparation of biologically and pharmacologically active molecules1,2,3,4,5

Uses

Reactant for:

Preparation of biologically and pharmacologically active molecules

Synthesis

110-85-0

627-42-9

13484-40-7

13484-41-8

Under nitrogen protection, 8.6 g (0.1 mol) of piperazine and 10.4 g of methanol were added to the reaction flask, 35 µl of hydrochloric acid (10.4 g, 0.1 mol) was added with stirring, and the internal temperature was controlled to 80 °C. Under the condition of keeping the internal temperature below 80 °C, 8.7 g (0.07 mol) of 2-bromoethanol was added slowly and dropwise over 0.5 h. Subsequently, the reaction was continued with stirring at the same temperature for 8 h. 36.9 g of colorless and transparent reaction solution was obtained. Gas chromatographic analysis showed a yield of 84.6% for N-(2-hydroxyethyl)piperazine, with a selectivity of 88.5% for N-(2-hydroxyethyl)piperazine, 7.7% for N,N'-bis(2-hydroxyethyl)piperazine, and 3.8% for the unknown component. Compared to the results of Example 2 in Table 1 , the reaction conditions were the same as in Example 2 when 3.8 g (0.04 mol) of 2-methoxyethyl ester was used in place of 2-bromoethanol. GC analysis showed a 70.1% yield of N-(2-methoxyethyl)piperazine with a selectivity of 83.4% for N-(2-methoxyethyl)piperazine, 15.0% for N,N'-bis(2-methoxyethyl)piperazine, and 1.6% for the unknown component. This result is consistent with the results of Example 5 in Table 1.

References

[1] Patent: JP5838628, 2016, B2. Location in patent: Paragraph 0056; 0059

1-(2-Methoxyethyl)piperazine Preparation Products And Raw materials

Raw materials

1-Bromo-2-methoxyethane Ethanol Sodium sulfate Triethylamine Piperazine

Hydrochloric acid Sodium bicarbonate Dichloromethane Sodium hydroxide 1-BOC-Piperazine

2-Methoxyethyl chloride

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Preparation Products

1-(2-Methoxyethyl)piperazine Suppliers

Global( 205)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Firsky International Trade (Wuhan) Co., Ltd	+8615387054039	admin@firsky-cn.com	China	427	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29822	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58

Supplier	Advantage
Firsky International Trade (Wuhan) Co., Ltd	58
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Accela ChemBio Inc.	58
Xiamen AmoyChem Co., Ltd	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
SIMAGCHEM CORP	58

View Lastest Price from 1-(2-Methoxyethyl)piperazine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-10-08	1-(2-Methoxyethyl)piperazine 13484-40-7	US $30.00 / L	1L	99%	20T	Firsky International Trade (Wuhan) Co., Ltd
2023-07-19	1-(2-Methoxyethyl)piperazine 13484-40-7	US $30.00 / KG	1KG	99%	20 Tons	Wuhan wingroup Pharmaceutical Co., Ltd
2022-01-26	1-(2-Methoxyethyl)piperazine 13484-40-7	US $0.00 / KG	1KG	98.4%	100 tons	Honest Joy Holdings Limited

1-(2-Methoxyethyl)piperazine
13484-40-7
US $30.00 / L
99%
Firsky International Trade (Wuhan) Co., Ltd

1-(2-Methoxyethyl)piperazine
13484-40-7
US $30.00 / KG
99%
Wuhan wingroup Pharmaceutical Co., Ltd

1-(2-Methoxyethyl)piperazine
13484-40-7
US $0.00 / KG
98.4%
Honest Joy Holdings Limited

1-(2-Methoxyethyl)piperazine Spectrum

1-(2-Methoxyethyl)piperazine(13484-40-7)¹HNMR 1-(2-Methoxyethyl)piperazine(13484-40-7)IR

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1-(2-METHOXYETHYL)PIPERAZINE RARECHEM AH CK 0124 Methoxyethylpiperazine 1-(2-Methoxyethyl)piperazine 98% 1-(2-METHOXYETHYL)-PIPERAZINE >98% 1-(2-Methoxyethyl)piperzazine 1-Methoxy-2-(piperazin-1-yl)ethane 4-(2-Methoxyethyl)piperazine N-(2-Methoxyethyl)piperazine 1-(2-Methoxyethyl)piperazine, 98% 5GR Methyl 2-(1-Piperazinyl)ethyl Ether gx1011-aM 1-(2-Methoxyethyl)-piperazine 2HCl 1-N- Methoxyethyl piperazine 1-(2-Methoxyethyl)piperazine, 97+% 1-(2-Methoxyethyl)piperazine> Piperazine, 1-(2-methoxyethyl)- 13484-40-7 Piperazines Heterocyclic Building Blocks Building Blocks Building Blocks C4 to C8 Chemical Synthesis Heterocyclic Building Blocks Building Blocks Heterocyclic Building Blocks Piperazines Amines and Anilines Heterocycles