ChemicalBook >> CAS DataBase List >>1,1-Cyclobutanedicarboxylic acid
1,1-Cyclobutanedicarboxylic acid
- CAS No.
- 5445-51-2
- Chemical Name:
- 1,1-Cyclobutanedicarboxylic acid
- Synonyms
- CYCLOBUTANE-1,1-DICARBOXYLIC ACID;1-Cyclobutanedicarboxylic acid;H2cbdca;226-651-2;1,1-Cyclobutanedicar;Carboplatin Impurity 1;Carboplatin impurity B;obutane-1,1-dicarboxyL;1,1-Dicarboxycyclobutane;Carboplatin EP Impurity B
- CBNumber:
- CB2315559
- Molecular Formula:
- C6H8O4
- Molecular Weight:
- 144.13
- MDL Number:
- MFCD00001325
- MOL File:
- 5445-51-2.mol
- MSDS File:
- SDS
Last updated:2026-01-13 13:16:48
| Product description | Number | Pack Size | Price |
| Cyclobutane-1,1-dicarboxylic acid 99% | C95803 | 5g | $60.9 |
| 1,1-Cyclobutanedicarboxylic Acid >98.0%(GC)(T) | C0769 | 5g | $38 |
| 1,1-Cyclobutanedicarboxylic Acid >98.0%(GC)(T) | C0769 | 25g | $107 |
| 1,1-Cyclobutanedicarboxylic Acid | B416503 | 100g | $205 |
| 1,1-Cyclobutanedicarboxylic Acid | B416503 | 25g | $75 |
| More product size | |||
| Melting point | 158 °C(lit.) |
|---|---|
| Boiling point | 222.71°C (rough estimate) |
| Density | 1.3217 (rough estimate) |
| refractive index | 1.5800 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | pK1:3.13 ;pK2:5.88 (25°C) |
| form | Fine Crystalline Powder |
| color | White |
| BRN | 2046031 |
| InChI | InChI=1S/C6H8O4/c7-4(8)6(5(9)10)2-1-3-6/h1-3H2,(H,7,8)(H,9,10) |
| InChIKey | CCQPAEQGAVNNIA-UHFFFAOYSA-N |
| SMILES | C1(C(O)=O)(C(O)=O)CCC1 |
| CAS DataBase Reference | 5445-51-2(CAS DataBase Reference) |
| FDA UNII | PV866VZU2U |
| NIST Chemistry Reference | 1,1-Cyclobutanedicarboxylic acid(5445-51-2) |
| EPA Substance Registry System | 1,1-Cyclobutanedicarboxylic acid (5445-51-2) |
| UNSPSC Code | 12352106 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45-28A | |||||||||
| RIDADR | UN 3261 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GU1335000 | |||||||||
| Hazard Note | Corrosive | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29172000 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Skin Corr. 1B | |||||||||
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
1,1-Cyclobutanedicarboxylic acid price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C95803 | Cyclobutane-1,1-dicarboxylic acid 99% | 5445-51-2 | 5g | $60.9 | 2026-03-19 | Buy |
| TCI Chemical | C0769 | 1,1-Cyclobutanedicarboxylic Acid >98.0%(GC)(T) | 5445-51-2 | 5g | $38 | 2026-03-19 | Buy |
| TCI Chemical | C0769 | 1,1-Cyclobutanedicarboxylic Acid >98.0%(GC)(T) | 5445-51-2 | 25g | $107 | 2026-03-19 | Buy |
| TRC | B416503 | 1,1-Cyclobutanedicarboxylic Acid | 5445-51-2 | 100g | $205 | 2021-12-16 | Buy |
| TRC | B416503 | 1,1-Cyclobutanedicarboxylic Acid | 5445-51-2 | 25g | $75 | 2021-12-16 | Buy |
1,1-Cyclobutanedicarboxylic acid Chemical Properties,Uses,Production
Uses
1,1-Cyclobutanedicarboxylic Acid(5445-51-2) is used in the design, studies and structural model of antitumor dicycloplatin a clinical cancer drug. Hydrolysis mechanism of second-generation anticancer drug carboplatin.
Chemical Properties
white fine crystalline powder
Uses
Cyclobutane-1,1-dicarboxylic acid can be used as:
- A reactant to synthesize lithium coordination polymer by treating with lithium carbonate.
- A ligand to prepare various lanthanide metal-organic frameworks (LnMOFs) via a solvothermal method. Eu+3 based MOF is applicable as a selective chemical sensor for detecting CH3OH due to its high luminescence quantum yield.
It can also be used as a starting material in the synthesis of carboplatin (cis-diammine(1,1-cyclobutanedicarboxyl-ate)platinum(II)).
Definition
ChEBI: Cyclobutane-1,1-dicarboxylic acid is a cyclobutanedicarboxylic acid. It is a conjugate acid of a cyclobutane-1,1-dicarboxylate(1-).
Application
1,1-Cyclobutanedicarboxylic acid can be used as:
A reactant to synthesize lithium coordination polymer by treating with lithium carbonate.
A ligand to prepare various lanthanide metal-organic frameworks (LnMOFs) via a solvothermal method. Eu+3 based MOF is applicable as a selective chemical sensor for detecting CH3OH due to its high luminescence quantum yield.
It can also be used as a starting material in the synthesis of carboplatin (cis-diammine(1,1-cyclobutanedicarboxyl-ate)platinum(II)).
1,1-Cyclobutanedicarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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Global( 556)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9541 | 58 |
| Suzhou Yangen Biotech Co.Ltd | +8615051547453 | christina@yangenbiotech.com | China | 230 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5235 | 58 |
| Hebei Dangtong Import and export Co LTD | +86-86-4001020630 +8619831957301 | admin@hbdangtong.com | China | 998 | 58 |
| Moxin Chemicals | +86-17320513646 +8617320513646 | anna@molcoo.com | China | 10000 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21592 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29821 | 58 |
Related articles
- Application of 1,1-Cyclobutanedicarboxylic acid in organic synthesis
- 1,1-Cyclobutanedicarboxylic acid serves as an intermediate in the synthesis of anticancer drugs, which is also plays a crucial....
- Dec 11，2025
- The synthesis method of 1,1-Cyclobutanedicarboxylic acid
- 1,1-Cyclobutanedicarboxylic acid was prepared by hydrolysis of the ethyl ester or half nitrile, 1-cyano-1-carboxycyclobutane.
- Sep 12，2024
View Lastest Price from 1,1-Cyclobutanedicarboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-21 | 1,1-Cyclobutanedicarboxylic acid
5445-51-2
|
US $0.00 / MG | 100MG | 98.0% | 1kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2026-03-20 | 1,1-Cyclobutanedicarboxylic acid
5445-51-2
|
US $100.00 / KG | 1KG | 99%min | 200TON | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2026-02-25 | 1,1-Cyclobutanedicarboxylic acid
5445-51-2
|
US $20.00-6.00 / kg | 1kg | 99% | 300tons | Hebei Dangtong Import and export Co LTD |
-
- 1,1-Cyclobutanedicarboxylic acid
5445-51-2
- US $0.00 / MG
- 98.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 1,1-Cyclobutanedicarboxylic acid
5445-51-2
- US $100.00 / KG
- 99%min
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 1,1-Cyclobutanedicarboxylic acid
5445-51-2
- US $20.00-6.00 / kg
- 99%
- Hebei Dangtong Import and export Co LTD
5445-51-2(1,1-Cyclobutanedicarboxylic acid)Related Search:
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Caboplatin IMpurity B (Cyclobutane-1,1-dicarboxylic acid)
1,1-Dicarboxylic acid cyclobutane
1,1-cyclobutanetwo forMic acid
1,1-Cyclobutanedicarboxylic acid, 99% 25GR
1,1-Cyclobutanedicarboxylic acid, 99% 5GR
1,1-Cyclobutanedicar
1-Cyclobutanedicarboxylic acid
Cyclobutane-1,1-dicarboxylic acid 99%
1,1-Dicarboxycyclobutane
1,1-Cyclobutanedicarboxylic acid,99%
Carboplatin Impurity 1
Carboplatin impurity B
226-651-2
1,1-CYCLOBUTANEDICARBOXYLIC ACID
1,1-Cyclobutanedicarboxylic acid for synthesis
Cyclobutane-1,1-DicarboxylicAcid,>98%
1,1-cyclobutanedicarboxylic
Cyclobutane-1,1-dicarboxylic
1,1-Cyclobutanedicarboxylic acid 99%
Carboplatin Impurity B (Cyclobutane-1,1-dicarboxylic acid)
Carboplatin EP Impurity B
1,1-Cyclobutanedicarboxylic acid, 99%, for synthesis
1,1-Cyclobutanedicarboxylic Acid >
1,1-CYCLOBUTANEDICARBOXYLIC ACID FOR SYN
obutane-1,1-dicarboxyL
H2cbdca
1, 1-Cyclobutanedicarboxylic Acid CAS 5445-51-2
1,1-cyclobutanedicarboxylic 1，
1,1-Cyclobutanedicarboxylic acidQ: What is
1,1-Cyclobutanedicarboxylic acid Q: What is the CAS Number of
1,1-Cyclobutanedicarboxylic acid Q: What is the storage condition of
1,1-Cyclobutanedicarboxylic acid Q: What are the applications of
1,1-Cyclobutanedicarboxylic acid
TIANFUCHEM-- 5445-51-2-- 1,1-Cyclobutanedicarboxylic acid in stock
1,1-Cyclobutanedicarboxylic acid (7CI, 8CI, 9CI, ACI)
Carboplatin Intermediates
1，1-Cycbobutanedicarboxylicacid
CYCLOBUTANE-1,1-DICARBOXYLIC ACID
5445-51-2
5445-52-2
Simple 4-Membered Ring Compounds
Cyclobutanes & Cyclobutenes
Carboxylic Acids
Carbonyl Compounds
Building Blocks
Organic Building Blocks
C6
pharmaceutical
Carboxylic Acids
Organic acids
Cyclobutanes & Cyclobutenes
Simple 4-Membered Ring Compounds
Carboxylic Acids
Ring Systems
Cycloalkanes
Carbonyl Compounds
bc0001
C6
