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6-Fluoronicotinic acid

6-Fluoronicotinic acid structure

CAS No.: 403-45-2

Chemical Name:: 6-Fluoronicotinic acid

Synonyms: uoronicotinic acid;6-Fluoronicotinicaci;6-Fluoronicotinc Acid;6-Floronicotinic acid;6-FLUORONICOTINIC ACID;6-Fluoronicotinicacid98%;6-FluoronicotinicAcid>6-Fluoronicotinic acid 98%;6-FLUOROPYRIDINE-3-FORMIC ACID;6-Fluoropyridin-3-carboxylic acid

CBNumber:: CB2316945

Molecular Formula:: C6H4FNO2

Molecular Weight:: 141.1

MDL Number:: MFCD01859863

MOL File:: 403-45-2.mol

MSDS File:: SDS

Last updated:2026-01-13 11:15:10

Product description	Number	Pack Size	Price
6-Fluoropyridine-3-carboxylic acid 97%	593761	250mg	$94.05
6-Fluoronicotinic Acid >98.0%(GC)	F0695	1g	$115
6-Fluoronicotinic Acid >98.0%(GC)	F0695	5g	$286
6-Fluoronicotinic Acid >98.0%(GC)	F0695	200mg	$30
6-FLUORONICOTINIC ACID 95.00%	HCH0019994	5G	$848.93
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6-Fluoronicotinic acid Properties

Melting point	144-148 °C(lit.)
Boiling point	309.4±22.0 °C(Predicted)
Density	1.419±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	3.41±0.10(Predicted)
form	powder to crystal
color	White to Orange to Green
InChI	InChI=1S/C6H4FNO2/c7-5-2-1-4(3-8-5)6(9)10/h1-3H,(H,9,10)
InChIKey	UJDLCTNVHJEBDG-UHFFFAOYSA-N
SMILES	C1=NC(F)=CC=C1C(O)=O
CAS DataBase Reference	403-45-2(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

HazardClass

IRRITANT

HS Code

29333990

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

6-Fluoronicotinic acid price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	593761	6-Fluoropyridine-3-carboxylic acid 97%	403-45-2	250mg	$94.05	2025-07-31	Buy
TCI Chemical	F0695	6-Fluoronicotinic Acid >98.0%(GC)	403-45-2	1g	$115	2025-07-31	Buy
TCI Chemical	F0695	6-Fluoronicotinic Acid >98.0%(GC)	403-45-2	5g	$286	2025-07-31	Buy
TCI Chemical	F0695	6-Fluoronicotinic Acid >98.0%(GC)	403-45-2	200mg	$30	2025-07-31	Buy
American Custom Chemicals Corporation	HCH0019994	6-FLUORONICOTINIC ACID 95.00%	403-45-2	5G	$848.93	2021-12-16	Buy

Product number	Packaging	Price	Buy
593761	250mg	$94.05	Buy
F0695	1g	$115	Buy
F0695	5g	$286	Buy
F0695	200mg	$30	Buy
HCH0019994	5G	$848.93	Buy

6-Fluoronicotinic acid Chemical Properties,Uses,Production

Chemical Properties

White to Orange to Green powder to crystal.

Uses

6-Fluoronicotinic acid is a fluorinated nicotinic acid that is a derivative of pyridine, with a carboxylic acid at 3-position and a fluorine at 6-position. It is used as a pharmaceutical intermediate and a molecular scaffold to synthesize tracers for positron emission tomography, for visualizing and measuring changes in metabolic processes.

References

[1] LATIFA RBAH-VIDAL. Early detection and longitudinal monitoring of experimental primary and disseminated melanoma using [¹⁰F]ICF01006, a highly promising melanoma PET tracer.[J]. European Journal of Nuclear Medicine and Molecular Imaging, 2012, 39 9: 1449-1461. DOI:10.1007/s00259-012-2168-y.
[2] FALGUNI BASULI. Fast indirect fluorine-18 labeling of protein/peptide using the useful 6-fluoronicotinic acid-2,3,5,6-tetrafluorophenyl prosthetic group: A method comparable to direct fluorination.[J]. Journal of labelled compounds & radiopharmaceuticals, 2017, 60 3 1: 168-175. DOI:10.1002/jlcr.3487.
[3] G. F. HAWKINS ARTHUR R. THE PREPARATION OF 5-FLUORONICOTINIC ACID AND 5-FLUORONICOTINAMIDE1[J]. The Journal of Organic Chemistry, 1949, 14 2: 328-332. DOI:10.1021/jo01154a021.
[4] Lal, Achchhe, and Devendra Kumar Singh. "Theoretical and Experimental Studies of Vibrational Spectra of 6-fluoronicotinc Acid."

6-Fluoronicotinic acid synthesis

Synthesis of 6-Fluoronicotinic acid from 2-Fluoro-5-methylpyridine

6-Fluoronicotinic acid Preparation Products And Raw materials

Raw materials

2-Amino-5-methylpyridine Sodium nitrite Fluoroboric acid Potassium permanganate 2-Fluoro-5-iodopyridine

2-Fluoro-5-methylpyridine 3-Pyridinecarbonyl chloride, 6-fluoro- (9CI) Nicotinic acid

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Preparation Products

3-Pyridinecarboxylic acid, 6-fluoro-, 1,1-diMethylethyl ester 5-Bromo-2-fluoropyridine

6-Fluoronicotinic acid Suppliers

Global( 351)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8753	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20128	58
Fuzhou Lista Biotechnology Co.,Ltd	+86-8615060109376; +86-8615060109376;	sallychris2021@gmail.com	China	123	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13620	58
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Fuzhou Lista Biotechnology Co.,Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Hi-Tech Chemistry Corp	58

View Lastest Price from 6-Fluoronicotinic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-01-05	6-Fluoronicotinic acid 403-45-2	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-12-01	6-Fluoronicotinic acid 403-45-2	US $0.00-0.00 / KG	1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-11-18	6-Fluoronicotinic acid 403-45-2	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited

6-Fluoronicotinic acid
403-45-2
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

6-Fluoronicotinic acid
403-45-2
US $0.00-0.00 / KG
98.0%
Shaanxi Dideu New Materials Co. Ltd

6-Fluoronicotinic acid
403-45-2
US $1.10 / g
99.00%
Dideu Industries Group Limited

6-Fluoronicotinic acid Spectrum

6-Fluoronicotinic acid(403-45-2)¹HNMR 6-Fluoronicotinic acid(403-45-2)FT-IR

403-45-2(6-Fluoronicotinic acid)Related Search:

Isonicotinic acid EPA 2-Fluoropyridine QUINOLINE-3-CARBOXYLIC ACID Xanthinol nicotinate

N,N-Dimethylpropionamide 2,2-Dimethylbutyryl chloride 2-Phenylbutyric acid 4,6-Difluoronicotinic acid 4-Chloro-5,6-difluoropyridine-3-carboxylic acid

2,6-Difluoropyridine-3-carboxylic acid 6-FLUORO-2-METHYLNICOTINIC ACID 6-FLUORONICOTINIC ACID METHYL ESTER 2-FLUORO-3-METHYL-PYRIDINE-5-CARBOXYLIC ACID 4-FLUORONICOTINIC ACID

2,6-Dichloro-5-fluoronicotinic acid 97%,2,6-DICHLORO-5-FLUORONICOTINIC ACID 3-FLUORONICOTINIC ACID 3-Bromo-2-fluoro--pyridine-5-carboxylic acid

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2-Fluoropyridine-5-carboxylic acid, 6-Fluoropyridine-3-carboxylic acid, 5-Carboxy-2-fluoropyridine, 3-Carboxy-6-fluoropyridine 6-Floronicotinic acid 6-Fluoronicotinc Acid 2-Fluoropyridine-5-carboxylic acid, 6-Fluoropyridine-3-carboxylic acid, 5-Carboxy-2-fluoropyridine 2-FLUOROPYRIDINE-5-CARBOXYLIC ACID 2-FLUORO-5-PYRIDINE CARBOXYLIC ACID 2-Fluoro-5-pyridine carboxylic acid(6-Fluoronicotinic acid) 6-FLUORONICOTINIC ACID 6-FLUOROPYRIDINE-3-CARBOXYLIC ACID 6-FLUOROPYRIDINE-3-FORMIC ACID 6-FLUORO-3-PYRIDINECARBOXYLIC ACID 6-Fluoronicotinic acid 98% 6-Fluoronicotinicacid98% 3-Pyridinecarboxylic acid,6-fluoro- 6-FluoronicotinicAcid> uoronicotinic acid 6-Fluoronicotinic acid ISO 9001：2015 REACH 6-Fluoropyridin-3-carboxylic acid 6-Fluoronicotinicaci 403-45-2 403-45-1 C6H4FNO2 Building Blocks Pyridines Heterocyclic Building Blocks C6 Chemical Synthesis Fluorinated Building Blocks Heterocyclic Building Blocks Heterocyclic Fluorinated Building Blocks Other Fluorinated Heterocycles Picolinic acid series Pyridine Pyridine series Pyridines Building Blocks Carboxy Boronic Acid API C6