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Ansofaxine (hydrochloride)

Ansofaxine (hydrochloride) Structure
Ansofaxine (hydrochloride) structure
CAS No.
916918-84-8
Chemical Name:
Ansofaxine (hydrochloride)
Synonyms
Toludesvenlafaxine Hydrochloride;LPM 570065,5-hydroxytryptamine Receptor,Dopamine Receptor,Ansofaxine hydrochloride,inhibit,Serotonin Receptor,LY-03005,LY 03005,Ansofaxine,Inhibitor,LPM-570065,5-HT Receptor;Y03005;LY03005;LPM570065;Ansofaxine (hydrochL;Venlafaxine EP Impurity23;Ansofaxine (hydrochloride),LY03005;Ansofaxine hydrochloride, 10 mM in DMSO;Toludesvenlafaxine Impurity 3(Hydrochloride)
CBNumber:
CB23339604
Molecular Formula:
C24H31NO3.ClH
Molecular Weight:
417.97
MDL Number:
MFCD31544376
MOL File:
916918-84-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
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Ansofaxine (hydrochloride) Properties

storage temp. Store at -20°C
solubility DMSO : 31.25 mg/mL (74.77 mM)
form Solid
color White to off-white
InChI InChI=1S/C24H31NO3.ClH/c1-18-7-9-20(10-8-18)23(26)28-21-13-11-19(12-14-21)22(17-25(2)3)24(27)15-5-4-6-16-24;/h7-14,22,27H,4-6,15-17H2,1-3H3;1H
InChIKey BVWFJKQJRNSYCR-UHFFFAOYSA-N
SMILES C(C1(CCCCC1)O)(C1C=CC(OC(C2C=CC(C)=CC=2)=O)=CC=1)CN(C)C.Cl
FDA UNII V6Z6K3OQX4

Ansofaxine (hydrochloride) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-7132 Ansofaxine hydrochloride 99.44% 916918-84-8 5mg $227 2026-06-04 Buy
ChemScene CS-7132 Ansofaxine hydrochloride 99.44% 916918-84-8 10mg $368 2026-06-04 Buy
ChemScene CS-7132 Ansofaxine hydrochloride 99.44% 916918-84-8 25mg $704 2026-06-04 Buy
ChemScene CS-7132 Ansofaxine hydrochloride 99.44% 916918-84-8 50mg $997 2026-06-04 Buy
ChemScene CS-7132 Ansofaxine hydrochloride 99.44% 916918-84-8 100mg $1354 2026-06-04 Buy
Product number Packaging Price Buy
CS-7132 5mg $227 Buy
CS-7132 10mg $368 Buy
CS-7132 25mg $704 Buy
CS-7132 50mg $997 Buy
CS-7132 100mg $1354 Buy

Ansofaxine (hydrochloride) Chemical Properties,Uses,Production

Uses

Ansofaxine hydrochloride (LY03005; LPM570065) is a triple reuptake inhibitor; inhibits serotonin, dopamine and norepinephrine reuptake with IC50 values of 723, 491 and 763 nM, respectively.

in vivo

Ansofaxine rapidly penetrates the rat striatum, converts into desvenlafaxine and exhibits larger total exposure compared with the administration of desvenlafaxine. Acute and chronic administration of oral suspension of ansofaxine increases the 5-HT, dopamine and norepinephrine levels more than the relative administration of desvenlafaxine. Unlike desvenlafaxine, acute administration of an intravenous ansofaxine solution does not induce the undesirable 90% decrease in extracellular 5-HT levels. The acute administration of ansofaxine shows a capped increase in extracellular 5-HT levels when combined with WAY-100635. Acute and chronic administration of ansofaxine reduces the immobility time more than the relative administration of desvenlafaxine[1].

IC 50

serotonin: 723 nM (IC50); Dopamine Receptor: 491 nM (IC50)

References

[1] Zhang R, et al. The effects of LPM570065, a novel triple reuptake inhibitor, on extracellular serotonin, dopamineand norepinephrine levels in rats. PLoS One. 2014 Mar 10;9(3):e91775. DOI:10.1371/journal.pone.0091775

Ansofaxine (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

Ansofaxine (hydrochloride) Suppliers

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
Shandong Jikun Biopharmaceutical Co., Ltd. 15020996564 16658695017 sales@jikungroup.com China 21 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9796 55
TOSUN PHARM 020-66392521-118 18922260391 3004261881@qq.com China 7994 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
InvivoChem +1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6378 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Supplier Advantage
Shandong Jikun Biopharmaceutical Co., Ltd. 58
MedChemexpress LLC 58
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Tianjin Kailiqi Biotechnology Co., Ltd. 55
TOSUN PHARM 58
BOC Sciences 58
TargetMol Chemicals Inc. 58
InvivoChem 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58

View Lastest Price from Ansofaxine (hydrochloride) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ansofaxine hydrochloride pictures 2026-07-15 Ansofaxine hydrochloride
916918-84-8
 $71.00-278.00 99.77% 10g TargetMol Chemicals Inc.
Toludesvenlafaxine Hydrochloride pictures 2025-12-19 Toludesvenlafaxine Hydrochloride
916918-84-8
 5kg 98%-102% 200kg Guangzhou Tosun Pharmaceutical Ltd

Ansofaxine (hydrochloride) Spectrum

Ansofaxine (hydrochloride)(916918-84-8)1HNMR

916918-84-8(Ansofaxine (hydrochloride))Related Search:

Immunology/Inflammation Compound Library Clinical Compound Library
Ansofaxine (hydrochloride),LY03005 LPM570065 LY03005 Ansofaxine (hydrochL Y03005 Ansofaxine hydrochloride, 10 mM in DMSO Venlafaxine EP Impurity23 LPM 570065,5-hydroxytryptamine Receptor,Dopamine Receptor,Ansofaxine hydrochloride,inhibit,Serotonin Receptor,LY-03005,LY 03005,Ansofaxine,Inhibitor,LPM-570065,5-HT Receptor Toludesvenlafaxine Hydrochloride Toludesvenlafaxine Impurity 3(Hydrochloride) 916918-84-8