MK 0767
- CAS No.
- 934017-32-0
- Chemical Name:
- MK 0767
- Synonyms
- MK 0767;Benzamide, 5-[(2,4-dioxo-5-oxazolidinyl)methyl]-2-methoxy-N-[[4-(trifluoromethyl)phenyl]methyl]-
- CBNumber:
- CB23357934
- Molecular Formula:
- C20H17F3N2O5
- Molecular Weight:
- 422.35
- MDL Number:
- MOL File:
- 934017-32-0.mol
- MSDS File:
- SDS
| Density | 1.381±0.06 g/cm3(Predicted) |
|---|---|
| pka | 5.78±0.70(Predicted) |
| FDA UNII | Y180U02GSB |
MK 0767 Chemical Properties,Uses,Production
Uses
DB12055 (MK-0767 analog) is a covalent SARS-CoV-2 3CL protease inhibitor. DB12055 has the potential for the study of dyslipidemia and diabetes mellitus[1].
References
[1] Ronda K Rippley, et al. Human pharmacokinetics and interconversion of enantiomers of MK-0767, a dual PPARalpha/gamma agonist. J Clin Pharmacol. 2007 Mar;47(3):323-33. DOI:10.1177/0091270006297141
[2] Ying Wang, et al. Multidimensional virtual screening approaches combined with drug repurposing to identify potential covalent inhibitors of SARS-CoV-2 3CL protease. J Biomol Struct Dyn. 2023;41(24):15262-15285. DOI:10.1080/07391102.2023.2193994
MK 0767 Preparation Products And Raw materials
Raw materials
Preparation Products
MK 0767 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Supplier | Advantage |
|---|---|
| career henan chemical co | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
