N-(Azido-PEG2)-N-Boc-PEG4-t-butyl ester
- CAS No.
- 2093153-83-2
- Chemical Name:
- N-(Azido-PEG2)-N-Boc-PEG4-t-butyl ester
- Synonyms
- WUN 53832;(N3-PEG2)(Boc)-N-PEG4-COOtBu;N-(Azido-PEG2)-N-Boc-PEG4-Boc;N-(Azido-PEG2)-N-Boc-PEG4-t-butyl ester
- CBNumber:
- CB23373684
- Molecular Formula:
- C26H50N4O10
- Molecular Weight:
- 578.696
- MDL Number:
- MFCD30723275
- MOL File:
- 2093153-83-2.mol
N-(Azido-PEG2)-N-Boc-PEG4-t-butyl ester Chemical Properties,Uses,Production
Description
N-(Azido-PEG2)-N-Boc-PEG4-t-butyl ester is a very useful branched PEG reagent with a terminal azide group, Boc protected amine, and a terminal t-butyl ester. The azide groups is very reactive with alkyne such as DBCO, BCN and propargyl reagnet via Click Chemistry. The protected amine can be deprotected under acidic conditions, and the t-butyl protected carboxyl group can be deprotected under mild acidic conditions.
Uses
N-(Azido-PEG2)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG2)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(Azido-PEG2)-N-Boc-PEG4-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
N-(Azido-PEG2)-N-Boc-PEG4-t-butyl ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32433 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2997 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-0431-80514535 19917294565 | et@chemextension.com | China | 3941 | 55 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4952 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85563444 18351873721 | purchase@synzest.com | China | 10434 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 3001317055@qq.com | China | 9633 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29757 | 58 |
| Shanghai Easy CDMO Co.,Ltd | 021-61734564 13854185395; | info@easycdmo.com | China | 10030 | 58 |
View Lastest Price from N-(Azido-PEG2)-N-Boc-PEG4-t-butyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-07 | N-(Azido-PEG2)-N-Boc-PEG4-t-butyl ester
2093153-83-2
|
US $0.00 / mg | 500mg | >95.00% | 500mg | Xian confluore Biological Technology Co., Ltd. |
-
- N-(Azido-PEG2)-N-Boc-PEG4-t-butyl ester
2093153-83-2
- US $0.00 / mg
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
