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1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione

CAS No.
660843-23-2
Chemical Name:
1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione
Synonyms
Mal-PEG2-NH2 (TFA);1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione;1-[2-[2-(2-Aminoethoxy)ethoxy]ethyl]-1H-pyrrole-2,5-dione Trifluoroacetate;O-(2-aminoethyl)-O'-(2-maleimidoethyl)ethylene glycol trifluoroacetate salt;1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate
CBNumber:
CB23376731
Molecular Formula:
C12H17F3N2O6
Molecular Weight:
342.27
MDL Number:
MFCD29041599
MOL File:
660843-23-2.mol
MSDS File:
SDS
Last updated:2025-04-17 18:22:24

1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione Properties

form Oil
color Off-white to light yellow

1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0200350 Mal-PEG2-NH2 TFA ≥98% 660843-23-2 100mg $133 2026-06-04 Buy
Matrix Scientific 291775 1-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate 660843-23-2 50.00mg $88 2026-05-19 Buy
Matrix Scientific 291775 1-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate 660843-23-2 100.00mg $160 2026-05-19 Buy
Matrix Scientific 291775 1-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate 660843-23-2 250.00mg $340 2026-05-19 Buy
aablocks AA01WT6M Mal-PEG2-amine TFA salt 98% 660843-23-2 50mg $58 2026-06-01 Buy
Product number Packaging Price Buy
CS-0200350 100mg $133 Buy
291775 50.00mg $88 Buy
291775 100.00mg $160 Buy
291775 250.00mg $340 Buy
AA01WT6M 50mg $58 Buy

1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione Chemical Properties, Uses, Production

Uses

Mal-PEG2-NH2 (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

Mal-PEG2-NH2 (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione Preparation Products And Raw materials

Raw materials

Preparation Products

1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione Suppliers

Global Suppliers ( 23)
Supplier Tel Email Country ProdList Advantage
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
SuZhou Medinoah Co.,LTD. 0512-69561983 13914027025 zhang_q@medinoah.com China 3925 58
Shanghai Thunder Biological Technology Co., Ltd. 18621609968 1162686636@qq.com China 1034 58
Shanxi Xuanran Import and Export Trade Co., Ltd. +8617735180244 mike_yan@xuanranglobal.com CHINA 4011 58
Accela ChemBio Inc. +1-858-6993322 +86-18019713315 info@accelachem.com United States 21189 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 54996 58
csynbio 15051477682 changming.pan@csynbio.com China 245 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 17801761073 Gsiyu@solarbio.com China 50460 58

View Latest Price from 1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Mal-PEG2-amine TFA salt pictures 2025-06-07 Mal-PEG2-amine TFA salt
660843-23-2
500mg >98.00% 500mg Xian confluore Biological Technology Co., Ltd.
1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione O-(2-aminoethyl)-O'-(2-maleimidoethyl)ethylene glycol trifluoroacetate salt Mal-PEG2-NH2 (TFA) 1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate 1-[2-[2-(2-Aminoethoxy)ethoxy]ethyl]-1H-pyrrole-2,5-dione Trifluoroacetate 660843-23-2 C2HF3O2C10H16N2O4