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4-HYDROXY-3-METHOXYCINNAMALDEHYDE

4-HYDROXY-3-METHOXYCINNAMALDEHYDE structure

CAS No.: 458-36-6

Chemical Name:: 4-HYDROXY-3-METHOXYCINNAMALDEHYDE

Synonyms: CONIFERYL ALDEHYDE;CONIFERALDEHYDE;2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)-;AT-51107;p-Coniferaldehyde;coniferylaldehydel;Eugenol EP Impurity K;Ferulic Acid Impurity 3;3-(4-Hydroxy-3-methoxyphenyl);Coniferaldehyde, 10 mM in DMSO

CBNumber:: CB2345336

Molecular Formula:: C10H10O3

Molecular Weight:: 178.18

MDL Number:: MFCD00075811

MOL File:: 458-36-6.mol

MSDS File:: SDS

Last updated:2025-09-25 17:15:13

Product description	Number	Pack Size	Price
4-Hydroxy-3-methoxycinnamaldehyde 98%	382051	1g	$101
4-Hydroxy-3-methoxycinnamaldehyde 98%	382051	5g	$362
4-Hydroxy-3-methoxycinnamaldehyde	FH74153	5G	$600
4-HYDROXY-3-METHOXYCINNAMALDEHYDE 95.00%	CHM0115024	1G	$653.23
Coniferaldehyde >98.0%	CS-0022807	50mg	$120
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4-HYDROXY-3-METHOXYCINNAMALDEHYDE Properties

Melting point	80-82 °C(lit.)
Boiling point	175 °C5 mm Hg(lit.)
Density	1.1562 g/cm3 (101.5 ºC)
refractive index	1.65635
Flash point	175°
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	9.65±0.31(Predicted)
form	Solid
color	Brown
Odor	at 50.00 % in dipropylene glycol. sweet graham cracker cookie bread crust bread baked toasted grain barley roasted barley vanilla custard dairy
Odor Type	bready
Stability	Air Sensitive
InChI	InChI=1S/C10H10O3/c1-13-10-7-8(3-2-6-11)4-5-9(10)12/h2-7,12H,1H3
InChIKey	DKZBBWMURDFHNE-UHFFFAOYSA-N
SMILES	C(=O)C=CC1=CC=C(O)C(OC)=C1
LogP	1.160
FDA UNII	06TPT01AD5
EPA Substance Registry System	2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)- (458-36-6)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-37/39
WGK Germany	3

4-HYDROXY-3-METHOXYCINNAMALDEHYDE price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	382051	4-Hydroxy-3-methoxycinnamaldehyde 98%	458-36-6	1g	$101	2025-07-31	Buy
Sigma-Aldrich	382051	4-Hydroxy-3-methoxycinnamaldehyde 98%	458-36-6	5g	$362	2025-07-31	Buy
Biosynth Carbosynth	FH74153	4-Hydroxy-3-methoxycinnamaldehyde	458-36-6	5G	$600	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0115024	4-HYDROXY-3-METHOXYCINNAMALDEHYDE 95.00%	458-36-6	1G	$653.23	2021-12-16	Buy
ChemScene	CS-0022807	Coniferaldehyde >98.0%	458-36-6	50mg	$120	2021-12-16	Buy

Product number	Packaging	Price	Buy
382051	1g	$101	Buy
382051	5g	$362	Buy
FH74153	5G	$600	Buy
CHM0115024	1G	$653.23	Buy
CS-0022807	50mg	$120	Buy

4-HYDROXY-3-METHOXYCINNAMALDEHYDE Chemical Properties,Uses,Production

Uses

4-Hydroxy-3-methoxycinnamaldehyde is suitable for use in a study to investigate the antioxidant and antiradical activities of ferulates using a β-carotene-linoleate model system and a DPPH radical scavenging assay, respectively.

Definition

ChEBI: A member of the class of cinnamaldehydes that is cinnamaldehyde substituted by a hydroxy group at position 4 and a methoxy group at position 3.

General Description

4-Hydroxy-3-methoxycinnamaldehyde is an isoflavonoid. It has been isolated from the insecticidally active hot dichloromethane extract of heartwood of Gliricidia sepium, seed kernels of Melia azedarach L and barks of Cinnamomum cebuense.

in vivo

Coniferaldehyde (0.05 mmol kg/day; i.p; for 6 weeks) activates the Nrf2 signaling pathway in primary chondrocytes and articular cartilage from the knee joints. And Coniferaldehyde alleviates cartilage destruction in OA mice^[2].

Animal Model:	B6 male mice (26 g; 8-10 weeks old), surgical-induced osteoarthritis (OA)^[2]
Dosage:	0.05 mmol kg/day (approx. 8.9 mg/kg)
Administration:	i.p; for 6 weeks
Result:	Evidently alleviated the medial meniscus cartilage damage in mice subjected to the destabilization.

4-HYDROXY-3-METHOXYCINNAMALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

4-HYDROXY-3-METHOXYCINNAMALDEHYDE Suppliers

Global( 171)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21620	55
Speranza Chemical Co., Ltd.	+86-86-075521030354 +8618688942810	sophieliu@speranzachem.com	China	925	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29850	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32434	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10239	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Speranza Chemical Co., Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Chengdu GLP biotechnology Co Ltd	58
Standardpharm Co. Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan ChemNorm Biotech Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Hubei Ipure Biology Co., Ltd	58

View Lastest Price from 4-HYDROXY-3-METHOXYCINNAMALDEHYDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-05-16	Coniferaldehyde 458-36-6	US $33.00-71.00 / mg		99.96%	10g	TargetMol Chemicals Inc.
	2019-07-14	4-HYDROXY-3-METHOXYCINNAMALDEHYDE 458-36-6	US $1.00 / KG	1KG	99%	25kg	Career Henan Chemical Co

Coniferaldehyde
458-36-6
US $33.00-71.00 / mg
99.96%
TargetMol Chemicals Inc.

4-HYDROXY-3-METHOXYCINNAMALDEHYDE
458-36-6
US $1.00 / KG
99%
Career Henan Chemical Co

4-HYDROXY-3-METHOXYCINNAMALDEHYDE Spectrum

4-HYDROXY-3-METHOXYCINNAMALDEHYDE(458-36-6)Raman 4-HYDROXY-3-METHOXYCINNAMALDEHYDE(458-36-6)FT-IR 4-HYDROXY-3-METHOXYCINNAMALDEHYDE(458-36-6)IR

458-36-6(4-HYDROXY-3-METHOXYCINNAMALDEHYDE)Related Search:

ETHYL HOMOVANILLATE Vanillylidenacetone RESCINNAMINE 3,4-DIMETHOXYBENZYLIDENEACETONE 3,4,5-TRIMETHOXYCINNAMIC ACID

Ferulic Acid trans-2,4,5-Trimethoxycinnamic acid 4-ACETOXY-3-METHOXYCINNAMIC ACID Curcumin 3,4-(METHYLENEDIOXY)BENZYLIDENEACETONE

HOMOBUTEIN 5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE trans-2,3,4-Trimethoxycinnamic acid 4-Hydroxy-3,5-dimethoxycinnamic acid 3,4-(Methylenedioxy)cinnamic acid

3,4-DIMETHOXYCINNAMIC ACID Ethyl 4-hydroxy-3-methoxycinnamate trans-4-Hydroxy-3-methoxycinnamaldehyde,4-HYDROXY-3-METHOXYCINNAMALDEHYDE

1of4

4'-hydroxy-3'-methoxyciаnaldehyde 2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)- 4-HYDROXY-3-METHOXYCINNAMALDEHDYE 2-Methoxy-4-(3-oxo-1-propenyl)phenol 2-Methoxy-4-(3-oxopropene-1-yl)phenol 3-(3-Methoxy-4-hydroxyphenyl)propenal 3-(4-Hydroxy-3-methoxyphenyl)-2-propenal CONIFERALDEHYDE CONIFERYL ALDEHYDE 4-HYDROXY-3-METHOXYCINNAMALDEHYDE 4-Hydroxy-3-methoxyzimtaldehyde p-Coniferaldehyde (E)-3-(4-hydroxy-3-Methoxyphenyl)acrylaldehyde coniferylaldehydel 3-(4-Hydroxy-3-Methoxyphenyl)acrylaldehyde 4-Hydroxy-3-MethoxycinnaMaldehyde 98% 3-(4-Hydroxy-3-methoxyphenyl) 4-Hydroxy-3-methoxycinnamaldehyde, 98%, from Balanophora involucrata Hook.f. Eugenol EP Impurity K AT-51107 Eugenol Impurity 11（Eugenol EP Impurity K） Ferulic Acid Impurity 3 4-Hydroxy-3-MethoxycinnaMaldehyde USP/EP/BP 4-Hydroxy-3-methoxycinnamaldehyde DISCONTINUED PLEASE SEE H973078 (E-ISOMER) Coniferaldehyde, 10 mM in DMSO 4-HYDROXY-3-METHOXYCINMALDEHYDE 458-36-6 HOCH3OC6H3CHCHCHO ALDEHYDE Building Blocks C10 to C21 Carbonyl Compounds Aldehydes Organic Building Blocks Aromatic Aldehydes & Derivatives (substituted)