ChemicalBook >> CAS DataBase List >>1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE structure

CAS No.: 67469-81-2

Chemical Name:: 1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE

Synonyms: CS-1078;GBR 12935 HCl;GBR-12935 2HCL;GBR-2935(dihydrochloride);GBR 12935 DIHYDROCHLORIDE;GBR 12935 (hydrochloride);GBR 12935 dihydrochloride, >=98%;1-(2-(BENZHYDRYLOXY)ETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE.2HCL;1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride;1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE

CBNumber:: CB2351371

Molecular Formula:: C28H35ClN2O

Molecular Weight:: 451.05

MDL Number:: MFCD00083175

MOL File:: 67469-81-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-20 17:00:22

Product description	Number	Pack Size	Price
GBR 12935 dihydrochloride ≥98% (TLC), powder	G9659	25mg	$195
GBR 12935 dihydrochloride ≥98% (TLC), powder	G9659	100mg	$629
GBR 12935 (hydrochloride) ≥98%	17700	10mg	$75
GBR 12935 (hydrochloride) ≥98%	17700	25mg	$149
GBR 12935 (hydrochloride) ≥98%	17700	50mg	$279
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1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Properties

storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	H₂O: 20 mg/mL with warming
form	powder
color	white
Water Solubility	H2O: 20mg/mL (with warming)
InChI	InChI=1S/C28H34N2O.ClH/c1-4-11-25(12-5-1)13-10-18-29-19-21-30(22-20-29)23-24-31-28(26-14-6-2-7-15-26)27-16-8-3-9-17-27;/h1-9,11-12,14-17,28H,10,13,18-24H2;1H
InChIKey	YMGXBGVMAOTRFZ-UHFFFAOYSA-N
SMILES	C(C1C=CC=CC=1)(C1C=CC=CC=1)OCCN1CCN(CCCC2C=CC=CC=2)CC1.Cl
UNSPSC Code	12352202
NACRES	NA.77

SAFETY

Risk and Safety Statements

PPE	Eyeshields, Gloves, type N95 (US)
WGK Germany	3
Storage Class	13 - Non Combustible Solids

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	G9659	GBR 12935 dihydrochloride ≥98% (TLC), powder	67469-81-2	25mg	$195	2023-01-07	Buy
Sigma-Aldrich	G9659	GBR 12935 dihydrochloride ≥98% (TLC), powder	67469-81-2	100mg	$629	2022-05-15	Buy
Cayman Chemical	17700	GBR 12935 (hydrochloride) ≥98%	67469-81-2	10mg	$75	2026-04-30	Buy
Cayman Chemical	17700	GBR 12935 (hydrochloride) ≥98%	67469-81-2	25mg	$149	2026-04-30	Buy
Cayman Chemical	17700	GBR 12935 (hydrochloride) ≥98%	67469-81-2	50mg	$279	2026-04-30	Buy

Product number	Packaging	Price	Buy
G9659	25mg	$195	Buy
G9659	100mg	$629	Buy
17700	10mg	$75	Buy
17700	25mg	$149	Buy
17700	50mg	$279	Buy

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Chemical Properties,Uses,Production

Uses

A very potent and selective inhibitor of dopamine uptake

Definition

ChEBI: A hydrochloride salt that is obtained by reaction of 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine with two equivalents of hydrogen chloride. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal memb anes).

Biochem/physiol Actions

GBR 12935 inhibits the dopamine and norepinephrine transporters with Kis of 21.5 nM and 225 nM, respectively. It does not inhibit the serotonin transporter (Ki = 6.5 mM). GBR 12935 binds to a nondopaminergic piperazine site in blood platelets and brain that has been identified as cytochrome P450.

in vivo

GBR 12935 dihydrochloride (1-32 mg/kg; repeat injection; 7 d) elevates locomotion activity to a greater extent in C57BL/6J mice than DBA/2J mice, and (10 mg/kg; injection; 7 d) results few mice sensitized to cocaine-induced stereotypy with repeated injections^[3].

Animal Model:	Adult male DBA/2J and C57BL/6J mice (22-30 g)^[3]
Dosage:	1.0, 3.2, 10, 32 mg/kg
Administration:	Repeat injection; for 7 days
Result:	Elevated locomotion activity to a greater extent in C57BL/6J mice than DBA/2J mice. No stereotypy was induced by an eighth day challenge of 10 mg/kg GBR 12935 dihydrochloride in mice pretreated with seven dally injections of either 32 mg/kg cocaine or saline.

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Suppliers

Global( 97)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471;	sales@sarms4muscle.com	China	10473	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43333	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
Jingmo (Xiamen) Biotechnology Co., Ltd	13621943973; 13621943973	sales@jamxmpharmatech.com	China	1180	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
TargetMol Chemicals Inc.	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
HANGZHOU LEAP CHEM CO., LTD.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Jingmo (Xiamen) Biotechnology Co., Ltd	58

View Lastest Price from 1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-20	GBR 12935 dihydrochloride 67469-81-2	US $50.00-108.00 / mg		99.82%	10g	TargetMol Chemicals Inc.
	2019-09-04	1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE 67469-81-2	US $1.00 / KG	1KG	98%	20kg	Career Henan Chemical Co

GBR 12935 dihydrochloride
67469-81-2
US $50.00-108.00 / mg
99.82%
TargetMol Chemicals Inc.

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE
67469-81-2
US $1.00 / KG
98%
Career Henan Chemical Co

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Spectrum

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE(67469-81-2)¹HNMR

67469-81-2(1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE)Related Search:

Diphenhydramine 1-(2-ETHOXYETHYL)PIPERAZINE 1-(3-PHENYLPROPYL)PIPERAZINE PIPERAZINE DIHYDROCHLORIDE Diphenhydramine Hydrochloride

1-(2-BENZYLOXY-ETHYL)-PIPERAZINE 2-(DIPHENYLMETHOXY)-N-METHYLETHYLAMINE Vanoxerine dihydrochloride 1-(2-Methoxyethyl)piperazine 1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE

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GBR 12935 dihydrochloride, >=98% GBR 12935 (hydrochloride) GBR 12935 DIHYDROCHLORIDE 1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE GBR-12935 2HCL GBR 12935 HCl 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride Piperazine,1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)-, hydrochloride (1:2) GBR-2935(dihydrochloride) 1-(2-(BENZHYDRYLOXY)ETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE.2HCL CS-1078 inhibit,Inhibitor,DAT,GBR 12935 dihydrochloride,Dopamine Transporter,SLC6A3 67469-81-2 C28H34N2O2HCl BioChemical Application Index Biochemicals and Reagents Cell Signaling Enzymes Enzymes, Inhibitors, and Substrates Substrates Xenobiotics and Drug Metabolism Inhibitors