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3,3-Diphenyl-L-alanine

3,3-Diphenyl-L-alanine Structure
3,3-Diphenyl-L-alanine structure
CAS No.
149597-92-2
Chemical Name:
3,3-Diphenyl-L-alanine
Synonyms
L-DiPhenylalanine;L-3,3-DIPHENYLALANINE;H-DPH-OH;H-Dip-OH;H-L-Dip-OH;CAS:149597-92-2;H-(3-PHENYL)PHE-OH;RARECHEM BK PT 0193;(S)-DIPHENYLALANINE;3-Diphenyl-L-alanine
CBNumber:
CB2352404
Molecular Formula:
C15H15NO2
Molecular Weight:
241.29
MDL Number:
MFCD01631989
MOL File:
149597-92-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:20:07
Product description Number Pack Size Price
3,3-Diphenyl-L-alanine ≥98.0% (HPLC) 86998 1g $282
3,3-Diphenyl-L-alanine ≥99%(ChiralHPLC) 04129 1G $95
3,3-Diphenyl-L-alanine ≥99%(ChiralHPLC) 04129 5G $360
3,3-Diphenyl-L-alanine ≥99%(ChiralHPLC) 04129 25G $1535
(S)-2-Amino-3,3-diphenylpropanoic acid >98% A67972 1g $122
More product size
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3,3-Diphenyl-L-alanine Properties

Melting point 234-240 °C
Boiling point 389.2±30.0 °C(Predicted)
Density 1.198±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form solid
pka 2.11±0.10(Predicted)
color White
Major Application peptide synthesis
InChI InChI=1/C15H15NO2/c16-14(15(17)18)13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13-14H,16H2,(H,17,18)/t14-/s3
InChIKey PECGVEGMRUZOML-AWEZNQCLSA-N
SMILES C([C@H](N)C(=O)O)(C1=CC=CC=C1)C1=CC=CC=C1 |&1:1,r|
CAS DataBase Reference 149597-92-2(CAS DataBase Reference)
FDA UNII L1ZWG54X8B
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H300
Precautionary statements  P264-P301+P310
PPE Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes  T,Xi
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1/PG 3
WGK Germany  2
HazardClass  6.1
PackingGroup  Ⅲ
HS Code  2922498590
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 2 Oral
NFPA 704
1
3 0

3,3-Diphenyl-L-alanine price More Price(59)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 86998 3,3-Diphenyl-L-alanine ≥98.0% (HPLC) 149597-92-2 1g $282 2023-06-20 Buy
Chem-Impex 04129 3,3-Diphenyl-L-alanine ≥99%(ChiralHPLC) 149597-92-2 1G $95 2026-05-19 Buy
Chem-Impex 04129 3,3-Diphenyl-L-alanine ≥99%(ChiralHPLC) 149597-92-2 5G $360 2026-05-19 Buy
Chem-Impex 04129 3,3-Diphenyl-L-alanine ≥99%(ChiralHPLC) 149597-92-2 25G $1535 2026-05-19 Buy
Synthonix A67972 (S)-2-Amino-3,3-diphenylpropanoic acid >98% 149597-92-2 1g $122 2026-05-06 Buy
Product number Packaging Price Buy
86998 1g $282 Buy
04129 1G $95 Buy
04129 5G $360 Buy
04129 25G $1535 Buy
A67972 1g $122 Buy

3,3-Diphenyl-L-alanine Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

3,3-Diphenyl-L-alanine is used as organic chemical synthesis intermediate.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

1-Imidazolidinecarboxylic acid, 2-(2,6-dichlorophenyl)-4-(diphenylmethyl)-5-oxo-3-[(1R)-1-phenylethyl]-, 1,1-dimethylethyl ester, (2R,4S)-

1004755-24-1

3,3-Diphenyl-L-alanine

149597-92-2

Step 2: 1,1-dimethylethyl-(2R)-(2,6-dichlorophenyl)-(4S)-(diphenylmethyl)-5-oxo-3-((1'R)-phenylethyl)tetrahydro-1H-1-imidazolecarboxylate (188 mg, 0.31 mmol) was dissolved in a solvent mixture of 7.5 mL of tetrahydrofuran and 1 mL of 1 M hydrochloric acid, and the atmosphere of the reaction vessel was replaced with nitrogen. . To the mixture was added 90 mg of 20% palladium-carbon hydroxide catalyst; the atmosphere was again replaced with nitrogen and then hydrogen. After 100 hours of reaction at room temperature and 2.2 MPa hydrogen pressure, the catalyst was separated by filtration. The resulting product was washed once with 5 mL of tetrahydrofuran and 3 mL of distilled water, respectively, and the solvent was removed under reduced pressure. To the mixture was added 7.5 mL of 6M hydrochloric acid; the mixture was heated and refluxed at an external temperature of 120-130°C for 2.5 hours. Thereafter, the reaction mixture was cooled to an external temperature of 0°C. After adjusting the pH to 6 to 7 by adding 30% aqueous sodium hydroxide solution thereto, the solvent was removed under reduced pressure. The amount of (S)-2-amino-3,3-diphenylpropionic acid contained in the residue was determined under the following analytical conditions. As a result, the yield was 76% and the ee value was 95.7%.

References

[1] Patent: EP2050738, 2009, A1. Location in patent: Page/Page column 39-40

3,3-Diphenyl-L-alanine Preparation Products And Raw materials

Raw materials

1-Imidazolidinecarboxylic acid, 2-(2,6-dichlorophenyl)-4-(diphenylmethyl)-5-oxo-3-[(1R)-1-phenylethyl]-, 1,1-dimethylethyl ester, (2R,4S)- Water Hydrogen Hydrochloric acid Tetrahydrofuran

Preparation Products

3,3-Diphenyl-L-alanine Suppliers

Global( 151)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29640 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
GL Biochem (Shanghai) Ltd. 		+86-021-61263370 +86-18901917034 CHINA 3904 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 18903 58
Baoji Guokang Healthchem co.,ltd 		+8615604608665 15604608665 dominicguo@gk-bio.com CHINA 9414 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52705 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
career henan chemical co 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
GL Biochem (Shanghai) Ltd. 		58
Dideu Industries Group Limited 		58
Baoji Guokang Healthchem co.,ltd 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
Nextpeptide Inc 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58

View Lastest Price from 3,3-Diphenyl-L-alanine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-3,3-Diphenylalanine pictures 2022-02-09 L-3,3-Diphenylalanine
149597-92-2
 1KG 99.0% 100 tons Honest Joy Holdings Limited
3,3-Diphenyl-L-alanine pictures 2019-07-06 3,3-Diphenyl-L-alanine
149597-92-2
 $1.00 1kg 95%-99% Career Henan Chemical Co

3,3-Diphenyl-L-alanine Spectrum

3,3-Diphenyl-L-alanine(149597-92-2)1HNMR

149597-92-2(3,3-Diphenyl-L-alanine)Related Search:

DL-beta-Homophenylalanine D-Alanine 6-Aminocaproic acid Biphenyl Chlorodiphenylphosphine
L-Alanine EC 2.6.1.2 Phenprobamate L-CYSTEIC ACID L-3,4-DIFLUOROPHENYLALANINE
L-3,5-DIFLUOROPHE Tris(hydroxymethyl)aminomethane Glycine Aminoethoxyvinyl glycine hydrochloride Fmoc-3,3-diphenyl-L-alanine
Phenylacetic acid Boc-3,3-Diphenyl-L-alanine 3,3-DIPHENYL-D-ALANINE

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L-Ala(3,3-diphenyl)-OH 3,3-DIPHENYL-L-ALANINE (S)-DIPHENYLALANINE (S)-2-AMINO-3,3-DIPHENYL-PROPIONIC ACID RARECHEM BK PT 0193 BETA-PHENYL-L-PHENYLALANINE H-DPH-OH H-ALA(3,3-DIPHENYL)-OH H-(3-PHENYL)PHE-OH beta-Phenyl-L-phenylalanin H-L-Dip-OH L-3,3-Diphenyl-Ala-OH (S)-2-amino-3,3-diphenylpropanoic acid β-Phenyl-L-phenylalanine 3-Diphenyl-L-alanine (2S)-2-Amino-3,3-diphenylpropanoic acid L-DiPhenylalanine L-DiPhenylalanine β-Phenyl-L-phenylalanine, (S)-2-Amino-3,3-diphenylpropionic acid L-Phenylalanine, b-phenyl- L-Phenylalanine, β-phenyl- 3,3-Diphenyl-L-alanine USP/EP/BP β-Phenyl-L-Phenylalanin CAS:149597-92-2 3,3-Diphenyl-L-alanine H-Dip-OH L-3,3-DIPHENYLALANINE L-DiPhenylalanine 149597-92-2 Alanine Derivatives Peptide Synthesis Unnatural Amino Acid Derivatives Specialty Synthesis a-amino Phenylalanine analogs and other aromatic alpha amino acids Amino Acids Amino Acid Derivatives Peptide unnatural amino acids