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6-Aminouracil

6-Aminouracil structure

CAS No.: 873-83-6

Chemical Name:: 6-Aminouracil

Synonyms: 6-AMINOPYRIMIDINE-2,4(1H,3H)-DIONE;6-AMINOPYRIMIDINE-2,4-DIOL;4-AMINO-2,6-DIHYDROXYPYRIMIDINE;4-ADHP;NSC 7367;NSC 15919;AKOS 92815;Aminuracil;Aminouracil;4-AMINOURACI

CBNumber:: CB2355975

Molecular Formula:: C4H5N3O2

Molecular Weight:: 127.1

MDL Number:: MFCD00006071

MOL File:: 873-83-6.mol

MSDS File:: SDS

Last updated:2025-09-05 20:24:49

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6-Aminouracil Properties

Melting point	≥360 °C(lit.)
Boiling point	235.85°C (rough estimate)
Density	1.4748 (rough estimate)
refractive index	1.5000 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Slightly, Heated), Methanol (Slightly)
form	Crystalline Powder
pka	3.76±0.10(Predicted)
color	Cream to light brown
Water Solubility	slightly soluble
BRN	120491
InChI	InChI=1S/C4H5N3O2/c5-2-1-3(8)7-4(9)6-2/h1H,(H4,5,6,7,8,9)
InChIKey	LNDZXOWGUAIUBG-UHFFFAOYSA-N
SMILES	C1(=O)NC(N)=CC(=O)N1
CAS DataBase Reference	873-83-6(CAS DataBase Reference)
EPA Substance Registry System	2,4(1H,3H)-Pyrimidinedione, 6-amino- (873-83-6)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P280f

Safety Statements

22-24/25

WGK Germany

RTECS

YQ8750000

10-23

TSCA

Yes

HS Code

29335995

Toxicity

LDLo par-mus: 2400 mg/kg CBCCT* 7,696,55

NFPA 704

	1
1		0

6-Aminouracil price More Price(43)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A50606	6-Aminouracil 97%	873-83-6	100g	$72	2025-07-31	Buy
TCI Chemical	A0658	6-Aminouracil >98.0%(T)	873-83-6	25g	$61	2025-07-31	Buy
TCI Chemical	A0658	6-Aminouracil >98.0%(T)	873-83-6	250g	$357	2025-07-31	Buy
TRC	A604935	6-Amino-2,4-dihydroxypyrimidine	873-83-6	250g	$135	2021-12-16	Buy
Usbiological	A1377-08	6-Amino-2,4-dihydroxypyrimidine	873-83-6	2.5g	$312	2021-12-16	Buy

Product number	Packaging	Price	Buy
A50606	100g	$72	Buy
A0658	25g	$61	Buy
A0658	250g	$357	Buy
A604935	250g	$135	Buy
A1377-08	2.5g	$312	Buy

6-Aminouracil Chemical Properties,Uses,Production

Chemical Properties

cream to light brown crystalline powder

Definition

ChEBI: 6-aminouracil is a pyrimidone.

Safety Profile

Moderately toxic by parenteralroute. When heated to decomposition it emits toxic fumesof NOx.

Synthesis

105-56-6

57-13-6

873-83-6

GENERAL METHOD: Ethyl cyanoacetate (0.1 mol) was mixed with urea, methylurea and/or methylthiourea (0.1 mol) in anhydrous ethanol (290 mL) containing sodium. The reaction mixture was refluxed for 10-12 hours and subsequently cooled to room temperature. Acidification was carried out by adjusting the pH to 6 with acetic acid. The resulting precipitate was washed with distilled water and dried in a desiccator overnight.1a was obtained in 69% yield with a melting point over 360°C (literature value ≥ 360°C).

Purification Methods

Purify the aminouracil by dissolving it in 3M aqueous NH3, filtering hot, and adding 3M formic acid until precipitation is complete. Cool, filter off (or centrifuge), wash well with cold H2O, then EtOH and dry it in air. Dry it further in a vacuum at ~80o. [Barlin & Pfeiderer J Chem Soc (B) 1424 1971, Beilstein 25 III/IV 4107.]

References

[1] Russian Journal of Organic Chemistry, 2002, vol. 38, # 7, p. 1053 - 1055
[2] Journal of Chemical Research, 2016, vol. 40, # 12, p. 771 - 777
[3] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1996, vol. 35, # 7, p. 662 - 668
[4] Australian Journal of Chemistry, 2007, vol. 60, # 2, p. 120 - 123
[5] Oriental Journal of Chemistry, 2010, vol. 26, # 4, p. 1281 - 1292

6-Aminouracil synthesis

Synthesis of 6-Aminouracil from Urea and Methyl cyanoacetate

6-Aminouracil Preparation Products And Raw materials

Raw materials

Urea 1,4-Dioxane Ethyl cyanoacetate Cyanoacetic acid Sodium

Ethanol

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Preparation Products

6-methyl-1H-Pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione

6-Aminouracil Suppliers

Global( 545)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58
Hebei Chuanghai Biotechnology Co., Ltd	+8617732866630	abby@chuanghaibio.com	China	8773	58
Hebei Mujin Biotechnology Co.,Ltd	+8613288715578	sales@hbmojin.com	China	12248	58
Hebei Junhua Import and Export Co., LTD	+85259680964	junhua1@hb-junhua.com	China	933	58
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29734	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13090	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29852	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58

Supplier	Advantage
Career Henan Chemica Co	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Hebei Junhua Import and Export Co., LTD	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58

View Lastest Price from 6-Aminouracil manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-30	6-Aminouracil 873-83-6	US $0.00-0.00 / kg	1kg	99%	1000kg	Hebei Junhua Import and Export Co., LTD
2025-09-04	6-Aminouracil 873-83-6	US $500.00 / g	100g	99%	200ton	Hebei Mujin Biotechnology Co.,Ltd
2025-06-24	6-Aminouracil 873-83-6	US $25.00 / ASSAYS	100ASSAYS	99.5%	100 mt	Hebei Chuanghai Biotechnology Co., Ltd

6-Aminouracil
873-83-6
US $0.00-0.00 / kg
99%
Hebei Junhua Import and Export Co., LTD

6-Aminouracil
873-83-6
US $500.00 / g
99%
Hebei Mujin Biotechnology Co.,Ltd

6-Aminouracil
873-83-6
US $25.00 / ASSAYS
99.5%
Hebei Chuanghai Biotechnology Co., Ltd

6-Aminouracil Spectrum

6-Aminouracil(873-83-6)MS 6-Aminouracil(873-83-6)¹HNMR 6-Aminouracil(873-83-6)¹³CNMR 6-Aminouracil(873-83-6)IR1 6-Aminouracil(873-83-6)IR2 6-Aminouracil(873-83-6)Raman

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4(6)-AMINOURACIL 6-AMINO-2,4-PYRIMIDINEDIOL 6-AMINO-2,4-DIHYDROXY-PYRIMIDINE 6-AMINOURACIL 6-AMINOPYRIMIDINE-2,4(1H,3H)-DIONE AURORA KA-377 4-AMINOURACIL 4-AMINO-2,6-DIHYDROXYPYRIMIDINE 4-ADHP 6-aminohexahydropyrimidine-2,4-dione Tofacitinib Impurity 187 6-Aminouracil (for AMILORIDE) 4-AMINO-2,6-DIHYDROXYPYRIMIDINE 4-Amino-2,6-dihydroxypyrimidine, 6-Amino-2,4-pyrimidinediol 6-Amino-2,4-dioxo-1,2,3,4-tetrahydropyrimidine 4-Amino-2,6-dihydroxypyrimidine ,97% 4-AMINO-2,6-DIHYDROXYPYRIMIDINE,98% 2-Hydroxy-6-amino-3,4-dihydropyrimidine-4-one 6-Amino-2,4(1H,3H)-pyrimidinedione 6-AMinouracil (4-AMINO-2,6-DIHYDROXYPYRIMIDINE) 4 - aMino - 2, 6-2 hydroxy pyriMidine 6-Aminouracil,98% 6-AMINOURACIL PURUM 98% 4-AMINO-2,6-DIHYDROXYPYRIMIDINE 98% 4-AMINO-2,6-DIHYDROXYPYRIMIDINE (4(6)-AMINOURACIL) NSC 15919 NSC 7367 4-Amino-2,6-dihydroxypyrimidine 4-Aminouracil 6-Amino-2,4-pyrimidinediol 6-Aminopyrimidine-2,4(1H,3H)-dione, 4-Amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidine 6-AMINOPYRIMIDINE-2,4-DIOL AKOS 92815 TIMTEC-BB SBB000054 3h)-pyrimidinedione,6-amino-4(1h 4-Amimouracil 6-amino-uraci 4-Amino-2,6-dihydroxypyrimidine~4-Aminouracil Aminouracil 4-Amino-2,6-dihydroxypyrimidine;6-Amino-2,4-pyrimidinediol; 6-Aminouracil; 6-Aminouracil; 6-Amino-2,4-pyrimidinediol 4-AMINO-2-6-DIHYDROXY-PYRIMIDINECRYSTALL INE 4-AMINOURACI 2,4(1H,3H)-Pyrimidinedione, 6-amino- (9CI) 6-Aminouracil,99% 4(6)-Aminouracil for synthesis 6-Aminouracil (for AMILORIDE) 2,4(1H,3H)-Pyrimidinedione, 6-amino- 2,6-DIHYDROXY-4-AMINOPYRIMIDINE(4-AMINOURACIL) 6-Aminouracil > Aminuracil 6-Aminouracil ISO 9001：2015 REACH 4-Amino-2,6-dihydroxypyrimidine (6-aminouracil) 6-Aminouracil (or) 4-Amino-2,6-dihydroxypyrimidine, (or) 6-Amino-2,4-pyrimidinediol: Tofacitinib Impurity02 873-83-6 876-83-6 H2NC4H3N2O2 Building Blocks Heterocyclic Building Blocks Pyrimidines Amines