ChemicalBook >> CAS DataBase List >>4-Hydroxyquinoline

4-Hydroxyquinoline

CAS No.
611-36-9
Chemical Name:
4-Hydroxyquinoline
Synonyms
KYNURINE;AKOS 222-32;4-QUINOLINOL;QUINOLIN-4-OL;4-HydroxyquinoL;4-Quinolinol 98%;4-Quinolinol >1H-Quinolin-4-one;4(1H)-QUINOLINONE;4-hydroxy-quinolin
CBNumber:
CB2372460
Molecular Formula:
C9H7NO
Molecular Weight:
145.16
MDL Number:
MFCD00006777
MOL File:
611-36-9.mol
MSDS File:
SDS
Last updated:2026-01-26 13:56:28
Product description Number Pack Size Price
4-Quinolinol 98% H58005 1g $26.7
4-Quinolinol 98% H58005 5g $123
4-Quinolinol >98.0%(GC)(T) Q0029 5g $63
4-Quinolinol >98.0%(GC)(T) Q0029 25g $249
4-Quinolinol 98% H58005 10g $192
More product size

4-Hydroxyquinoline Properties

Melting point 200-202 °C(lit.)
Boiling point 264.27°C (rough estimate)
Density 1.1555 (rough estimate)
refractive index 1.4500 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in methanol.
pka 2.23, 11.28(at 20℃)
form Crystalline Powder or Needles
color Light beige to yellow
Water Solubility 4.8g/L(15 ºC)
BRN 1524969
InChI 1S/C9H7NO/c11-9-5-6-10-8-4-2-1-3-7(8)9/h1-6H,(H,10,11)
InChIKey PMZDQRJGMBOQBF-UHFFFAOYSA-N
SMILES Oc1ccnc2ccccc12
LogP 2.450 (est)
CAS DataBase Reference 611-36-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII M1O131WXFO
NIST Chemistry Reference 4-Quinolinol(611-36-9)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  VC4070000
HS Code  29334900
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

4-Hydroxyquinoline price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H58005 4-Quinolinol 98% 611-36-9 1g $26.7 2025-07-31 Buy
Sigma-Aldrich H58005 4-Quinolinol 98% 611-36-9 5g $123 2025-07-31 Buy
TCI Chemical Q0029 4-Quinolinol >98.0%(GC)(T) 611-36-9 5g $63 2025-07-31 Buy
TCI Chemical Q0029 4-Quinolinol >98.0%(GC)(T) 611-36-9 25g $249 2025-07-31 Buy
Sigma-Aldrich H58005 4-Quinolinol 98% 611-36-9 10g $192 2025-07-31 Buy
Product number Packaging Price Buy
H58005 1g $26.7 Buy
H58005 5g $123 Buy
Q0029 5g $63 Buy
Q0029 25g $249 Buy
H58005 10g $192 Buy

4-Hydroxyquinoline Chemical Properties,Uses,Production

Description

4-Hydroxyquinoline is a quinoline alkaloid that has been found in Z. lotus honeys. It is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules such as 2-heptyl-3-hydroxy-4(1H)-quinolone and 2-nonyl-3-hydroxy-4-quinolone. 4-Hydroxyquinoline has been used as a precursor in the synthesis of compounds with antibacterial activity. It has also been used as a fluorescent detection reagent for iron(III) in bovine liver samples.

Chemical Properties

LIGHT BEIGE TO YELLOWISH CRYST. POWDER OR NEEDLES

Uses

4-Hydroxyquinolineis is a raw material in medical research, a hydroxylated quinoline derivative with antimicrobial activity. 4-Hydroxyquinoline showed growth-inhibitory effects against intestinal bacteria. 4-Hydroxyquinoline act as sacrifi cial scavengers of the photogenerated oxygen species and has been shown to prevent the photodegradation of riboflavin.

Definition

ChEBI: A monohydroxyquinoline carrying a hydroxy group at position 4.

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1264, 1946 DOI: 10.1021/ja01211a038

General Description

4-Quinolinol (4-quinolone) is a quinolone compound which forms the core moiety of antibacterials such as norfloxacin, nalidixic acid, ciprofloxacin and cinoxacin.

Biological Activity

4-hydroxyquinoline is a hydroxylated quinoline derivative with antimicrobial activity. it shows growth-inhibitory effects against intestinal bacteria. it also can be used as sacrificial scavengers of the photogenerated oxygen species.

References

[1] F. KHALLOUKI. HPLC-ESI-MS and GC-EI-MS Identification and Quantitation of Polyphenolics and Alkaloids in Moroccan Jujube Honeys[J]. Journal of Apicultural Science, 2020, 64 1: 287-299. DOI: 10.2478/jas-2020-0029
[2] STEPHAN HEEB. Quinolones: from antibiotics to autoinducers[J]. FEMS microbiology reviews, 2011, 35 2: 247-274. DOI: 10.1111/j.1574-6976.2010.00247.x
[3] MARIE-GRATIA KAYIRERE . Synthesis and antibacterial activity of new 4-alkoxy, 4-aminoalkyl and 4-alkylthioquinoline derivatives[J]. European Journal of Medicinal Chemistry, 1998, 33 1: Pages 55-63. DOI: 10.1016/s0223-5234(99)80076-2
[4] GEORGE C. RAGOS  Prodromos B I  Mavroudis A Demertzis. A high-sensitive spectrofluorimetric method for the determination of micromolar concentrations of iron(III) in bovine liver with 4-hydroxyquinoline[J]. Farmaco (Societa chimica italiana: 1989), 1998, 53 8: Pages 611-616. DOI: 10.1016/s0014-827x(98)00070-6

62-53-3
611-36-9
Synthesis of 4-Hydroxyquinoline from Aniline
Global( 486)Suppliers
Supplier Tel Email Country ProdList Advantage
Yantai Fenglu Fine Chemical Co. LTD
+86-+undefined-008618315825527 kevin.wang@xhtechgroup.com China 122 58
Shanghai Yongzeng Technology Co.,Ltd
+8613818947575 sales@yongzchem.com China 142 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8753 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5242 58
Hefei Lbao Physical & Chemical Science Co.,Ltd
+1-5184799099 lbaochemicals@gmail.com China 674 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-2158073036 info@dakenam.com China 13799 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3009 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29831 58
NINGBO INNO PHARMCHEM CO., LTD.
13867897135 sales@nbinno.com CHINA 923 58

View Lastest Price from 4-Hydroxyquinoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Hydroxyquinoline pictures 2026-02-15 4-Hydroxyquinoline
611-36-9
US $0.00 / kg 1kg 98% Customise Hefei Lbao Physical & Chemical Science Co.,Ltd
4-Hydroxyquinoline pictures 2026-02-02 4-Hydroxyquinoline
611-36-9
US $0.00 / kg 1kg 99%min 100kgs Shanghai Yongzeng Technology Co.,Ltd
4-Hydroxyquinoline pictures 2026-01-30 4-Hydroxyquinoline
611-36-9
US $10.00-8.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
QUINOLIN-4-OL QUINOLIN-4(1H)-ONE KYNURINE 4-hydroxy-quinolin 1H-Quinolin-4-one Quinoline, 4-hydroxy- 4-Hydroxyquinoline98% 4-Quinolinol,4-Hydroxyquinoline 4-Hydroxyquinoline, 98% 10GR 4-hydroxyquatolate 4-Quinolinol 98% 4(1H)-QUINOLINONE 4-QUINOLINOL 4-HYDROXYQUINOLINE 4-HYDROXY-1-AZANAPHTHALENE HYDROXYQUINOLINE,4- 4-Hydroxyquinoline, >=98.5% AKOS 222-32 4-Quinolinol > 4-HydroxyquinoL 4-Hydroxyquinoline ISO 9001:2015 REACH Bedaquiline Impurity 15 4-Hydroxyquinoline, 10 mM in DMSO 4-Hydroxyquinoline, 95% 4-Hydroxyquinoline-d6 2-(3-((1R,2S)-4-(dimethylamino)-2-hydroxy-2-(naphthalen-1-yl)-1-phenylbutyl)-2-methoxyquinolin-6-yl)fumaric acid 611-36-9 C9H8NO ALCOHOL Hydroxyquinolines Quinolines Building Blocks Heterocyclic Building Blocks Building Blocks C8 to C10 Chemical Synthesis Heterocyclic Building Blocks Quinoline&Isoquinoline Quinolines Hydroxyquinolines quinoline Quinolines, Quinazolines and derivatives Heterocyclic Series Alcohols and Derivatives Heterocycles