4-Hydroxyquinoline
- CAS No.
- 611-36-9
- Chemical Name:
- 4-Hydroxyquinoline
- Synonyms
- KYNURINE;AKOS 222-32;4-QUINOLINOL;QUINOLIN-4-OL;4-HydroxyquinoL;4-Quinolinol 98%;4-Quinolinol >1H-Quinolin-4-one;4(1H)-QUINOLINONE;4-hydroxy-quinolin
- CBNumber:
- CB2372460
- Molecular Formula:
- C9H7NO
- Molecular Weight:
- 145.16
- MDL Number:
- MFCD00006777
- MOL File:
- 611-36-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Quinolinol 98% | H58005 | 1g | $26.7 |
| 4-Quinolinol 98% | H58005 | 5g | $123 |
| 4-Quinolinol >98.0%(GC)(T) | Q0029 | 5g | $63 |
| 4-Quinolinol >98.0%(GC)(T) | Q0029 | 25g | $249 |
| 4-Quinolinol 98% | H58005 | 10g | $192 |
| More product size | |||
| Melting point | 200-202 °C(lit.) |
|---|---|
| Boiling point | 264.27°C (rough estimate) |
| Density | 1.1555 (rough estimate) |
| refractive index | 1.4500 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in methanol. |
| pka | 2.23, 11.28(at 20℃) |
| form | Crystalline Powder or Needles |
| color | Light beige to yellow |
| Water Solubility | 4.8g/L(15 ºC) |
| BRN | 1524969 |
| InChI | 1S/C9H7NO/c11-9-5-6-10-8-4-2-1-3-7(8)9/h1-6H,(H,10,11) |
| InChIKey | PMZDQRJGMBOQBF-UHFFFAOYSA-N |
| SMILES | Oc1ccnc2ccccc12 |
| LogP | 2.450 (est) |
| CAS DataBase Reference | 611-36-9(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | M1O131WXFO |
| NIST Chemistry Reference | 4-Quinolinol(611-36-9) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VC4070000 | |||||||||
| HS Code | 29334900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4-Hydroxyquinoline price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H58005 | 4-Quinolinol 98% | 611-36-9 | 1g | $26.7 | 2025-07-31 | Buy |
| Sigma-Aldrich | H58005 | 4-Quinolinol 98% | 611-36-9 | 5g | $123 | 2025-07-31 | Buy |
| TCI Chemical | Q0029 | 4-Quinolinol >98.0%(GC)(T) | 611-36-9 | 5g | $63 | 2025-07-31 | Buy |
| TCI Chemical | Q0029 | 4-Quinolinol >98.0%(GC)(T) | 611-36-9 | 25g | $249 | 2025-07-31 | Buy |
| Sigma-Aldrich | H58005 | 4-Quinolinol 98% | 611-36-9 | 10g | $192 | 2025-07-31 | Buy |
4-Hydroxyquinoline Chemical Properties,Uses,Production
Description
4-Hydroxyquinoline is a quinoline alkaloid that has been found in Z. lotus honeys. It is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules such as 2-heptyl-3-hydroxy-4(1H)-quinolone and 2-nonyl-3-hydroxy-4-quinolone. 4-Hydroxyquinoline has been used as a precursor in the synthesis of compounds with antibacterial activity. It has also been used as a fluorescent detection reagent for iron(III) in bovine liver samples.
Chemical Properties
LIGHT BEIGE TO YELLOWISH CRYST. POWDER OR NEEDLES
Uses
4-Hydroxyquinolineis is a raw material in medical research, a hydroxylated quinoline derivative with antimicrobial activity. 4-Hydroxyquinoline showed growth-inhibitory effects against intestinal bacteria. 4-Hydroxyquinoline act as sacrifi cial scavengers of the photogenerated oxygen species and has been shown to prevent the photodegradation of riboflavin.
Definition
ChEBI: A monohydroxyquinoline carrying a hydroxy group at position 4.
Synthesis Reference(s)
Journal of the American Chemical Society, 68, p. 1264, 1946 DOI: 10.1021/ja01211a038
General Description
4-Quinolinol (4-quinolone) is a quinolone compound which forms the core moiety of antibacterials such as norfloxacin, nalidixic acid, ciprofloxacin and cinoxacin.
Biological Activity
4-hydroxyquinoline is a hydroxylated quinoline derivative with antimicrobial activity. it shows growth-inhibitory effects against intestinal bacteria. it also can be used as sacrificial scavengers of the photogenerated oxygen species.
References
[1] F. KHALLOUKI. HPLC-ESI-MS and GC-EI-MS Identification and Quantitation of Polyphenolics and Alkaloids in Moroccan Jujube Honeys[J]. Journal of Apicultural Science, 2020, 64 1: 287-299. DOI: 10.2478/jas-2020-0029
[2] STEPHAN HEEB. Quinolones: from antibiotics to autoinducers[J]. FEMS microbiology reviews, 2011, 35 2: 247-274. DOI: 10.1111/j.1574-6976.2010.00247.x
[3] MARIE-GRATIA KAYIRERE . Synthesis and antibacterial activity of new 4-alkoxy, 4-aminoalkyl and 4-alkylthioquinoline derivatives[J]. European Journal of Medicinal Chemistry, 1998, 33 1: Pages 55-63. DOI: 10.1016/s0223-5234(99)80076-2
[4] GEORGE C. RAGOS Prodromos B I Mavroudis A Demertzis. A high-sensitive spectrofluorimetric method for the determination of micromolar concentrations of iron(III) in bovine liver with 4-hydroxyquinoline[J]. Farmaco (Societa chimica italiana: 1989), 1998, 53 8: Pages 611-616. DOI: 10.1016/s0014-827x(98)00070-6
4-Hydroxyquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Yantai Fenglu Fine Chemical Co. LTD | +86-+undefined-008618315825527 | kevin.wang@xhtechgroup.com | China | 122 | 58 |
| Shanghai Yongzeng Technology Co.,Ltd | +8613818947575 | sales@yongzchem.com | China | 142 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8753 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5242 | 58 |
| Hefei Lbao Physical & Chemical Science Co.,Ltd | +1-5184799099 | lbaochemicals@gmail.com | China | 674 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13799 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29831 | 58 |
| NINGBO INNO PHARMCHEM CO., LTD. | 13867897135 | sales@nbinno.com | CHINA | 923 | 58 |
View Lastest Price from 4-Hydroxyquinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-02-15 | 4-Hydroxyquinoline
611-36-9
|
US $0.00 / kg | 1kg | 98% | Customise | Hefei Lbao Physical & Chemical Science Co.,Ltd | |
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2026-02-02 | 4-Hydroxyquinoline
611-36-9
|
US $0.00 / kg | 1kg | 99%min | 100kgs | Shanghai Yongzeng Technology Co.,Ltd | |
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2026-01-30 | 4-Hydroxyquinoline
611-36-9
|
US $10.00-8.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-

- 4-Hydroxyquinoline
611-36-9
- US $0.00 / kg
- 98%
- Hefei Lbao Physical & Chemical Science Co.,Ltd
-

- 4-Hydroxyquinoline
611-36-9
- US $0.00 / kg
- 99%min
- Shanghai Yongzeng Technology Co.,Ltd
-

- 4-Hydroxyquinoline
611-36-9
- US $10.00-8.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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