5-Nitro-6-methyluracil
- CAS No.
- 16632-21-6
- Chemical Name:
- 5-Nitro-6-methyluracil
- Synonyms
- NSC 40201;6-Methyl-5-Nit;-5-nitropyrimidine;6-metyl-5-nitrouracil;6-methyl-5-nitrouracil;5-NITRO-6-METHYLURACIL;2,4-Dihydroxy-6-methyL;6-Methyl-5-nitrouracil >5-Nitro-6-methyluracil ,98%;2,4-Dihydroxy-6-methyl-5-Nitro
- CBNumber:
- CB2373609
- Molecular Formula:
- C5H5N3O4
- Molecular Weight:
- 171.11
- MDL Number:
- MFCD00051201
- MOL File:
- 16632-21-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 6-Methyl-5-nitrouracil >95.0%(HPLC)(T) | M2506 | 1g | $16 |
| 6-Methyl-5-nitrouracil >95.0%(HPLC)(T) | M2506 | 5g | $33 |
| 6-METHYL-5-NITROPYRIMIDINE-2,4-DIONE 97% | 64041 | 5G | $19 |
| 6-METHYL-5-NITROPYRIMIDINE-2,4-DIONE 97% | 64041 | 10G | $36 |
| 5-Nitro-6-methyluracil 97% | N40978 | 1g | $25 |
| More product size | |||
| Melting point | 290-291°C dec. |
|---|---|
| Density | 1.58±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMF, DMSO, Hot Methanol, Hot Water |
| form | Solid |
| pka | 6.24±0.10(Predicted) |
| color | Light Yellow Crystalline |
| Water Solubility | Soluble in DMF, DMSO, hot methanol and hot water. |
| InChI | InChI=1S/C5H5N3O4/c1-2-3(8(11)12)4(9)7-5(10)6-2/h1H3,(H2,6,7,9,10) |
| InChIKey | LIVYMRJSNFHYEN-UHFFFAOYSA-N |
| SMILES | C1(=O)NC(C)=C([N+]([O-])=O)C(=O)N1 |
| CAS DataBase Reference | 16632-21-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H318-H335-H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-37/38-41-40 | |||||||||
| Safety Statements | 26-39-36-22 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29335990 | |||||||||
| NFPA 704 |
|
5-Nitro-6-methyluracil price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M2506 | 6-Methyl-5-nitrouracil >95.0%(HPLC)(T) | 16632-21-6 | 1g | $16 | 2025-07-31 | Buy |
| TCI Chemical | M2506 | 6-Methyl-5-nitrouracil >95.0%(HPLC)(T) | 16632-21-6 | 5g | $33 | 2025-07-31 | Buy |
| AstaTech | 64041 | 6-METHYL-5-NITROPYRIMIDINE-2,4-DIONE 97% | 16632-21-6 | 5G | $19 | 2026-04-30 | Buy |
| AstaTech | 64041 | 6-METHYL-5-NITROPYRIMIDINE-2,4-DIONE 97% | 16632-21-6 | 10G | $36 | 2026-04-30 | Buy |
| Synthonix | N40978 | 5-Nitro-6-methyluracil 97% | 16632-21-6 | 1g | $25 | 2026-05-06 | Buy |
5-Nitro-6-methyluracil Chemical Properties,Uses,Production
Chemical Properties
Light Yellow Crystalline Solid
Uses
A synthetic intermediate
Uses
5-Nitro-6-methyluracil, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
Synthesis
626-48-2
16632-21-6
The general procedure for the synthesis of 2,4-dihydroxy-6-methyl-5-nitropyrimidine from 6-methyluracil was as follows: the procedure was adapted from the Journal of Medicinal Chemistry. 6-Methylpyrimidine-2,4(1H,3H)-dione (7.0 g, 55.56 mmol) was slowly added to ice-cooled but concentrated sulfuric acid (26 mL), and the rate of addition was controlled to keep the internal temperature of the reaction system from exceeding 40 °C. Subsequently, fuming nitric acid (5.2 mL) was slowly added dropwise to the reaction mixture at a temperature below 15 °C. After completion of the dropwise addition, the cooling bath was removed and the reaction mixture was stirred at room temperature for 30 min. The reaction solution was carefully poured into 100 mL of crushed ice and stirred for 10 minutes before collecting the solid product that precipitated. The solid was washed with cold water and then dried under vacuum in the presence of phosphorus pentoxide. A yellow-green solid of 6-methyl-5-nitropyrimidine-2,4(1H,3H)-dione (7.92 g, 83% yield) was finally obtained.
References
[1] Journal of Chemical Research, Miniprint, 1989, # 9, p. 2086 - 2097
[2] Patent: WO2009/62258, 2009, A1. Location in patent: Page/Page column 97-98
[3] Synthetic Communications, 2007, vol. 37, # 14, p. 2421 - 2431
[4] ChemMedChem, 2018, vol. 13, # 2, p. 178 - 185
[5] Patent: CN105906621, 2016, A. Location in patent: Paragraph 0030
5-Nitro-6-methyluracil Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29817 | 58 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451682 | act@arborchemical.com | CHINA | 904 | 58 |
| Changzhou Carman Chemical Co., Ltd. | 15061933924 | CHINA | 514 | 58 | |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 5-Nitro-6-methyluracil manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-17 | 5-Nitro-6-methyluracil
16632-21-6
|
US $2.00-5.00 / kg | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2025-11-18 | 5-Nitro-6-methyluracil
16632-21-6
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2022-02-10 | 2,4-Dihydroxy-6-methyl-5-nitropyrimidine
16632-21-6
|
US $0.00 / KG | 1KG | 98.7% | 100 tons | Honest Joy Holdings Limited |
-
- 5-Nitro-6-methyluracil
16632-21-6
- US $2.00-5.00 / kg
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 5-Nitro-6-methyluracil
16632-21-6
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 2,4-Dihydroxy-6-methyl-5-nitropyrimidine
16632-21-6
- US $0.00 / KG
- 98.7%
- Honest Joy Holdings Limited
