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(3-Amino-5-nitrophenyl)methanol

(3-Amino-5-nitrophenyl)methanol Structure
(3-Amino-5-nitrophenyl)methanol structure
CAS No.
90390-46-8
Chemical Name:
(3-Amino-5-nitrophenyl)methanol
Synonyms
(3-AMINO-5-NITROPHENYL)METHANO;3-Amino-5-nitrobenzenemethanol;(3-Amino-5-nitrophenyl)methanol;3-(Hydroxymethyl)-5-nitroaniline;Benzenemethanol, 3-amino-5-nitro-
CBNumber:
CB2377203
Molecular Formula:
C7H8N2O3
Molecular Weight:
168.15
MDL Number:
MFCD08236778
MOL File:
90390-46-8.mol
MSDS File:
SDS
Last updated:2026-09-12 18:50:38
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(3-Amino-5-nitrophenyl)methanol Properties

Boiling point 425.9±30.0 °C(Predicted)
Density 1.432±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 13.71±0.10(Predicted)
Appearance Light yellow to green yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338

(3-Amino-5-nitrophenyl)methanol price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS32513 (3-Amino-5-nitrophenyl)methanol 98% 90390-46-8 1g $72 2026-06-04 Buy
Activate Scientific AS32513 (3-Amino-5-nitrophenyl)methanol 98% 90390-46-8 5g $309 2026-06-04 Buy
Matrix Scientific 074465 (3-Amino-5-nitrophenyl)methanol 90390-46-8 250.00mg $260 2026-05-18 Buy
Matrix Scientific 074465 (3-Amino-5-nitrophenyl)methanol 90390-46-8 1.00g $559 2026-05-18 Buy
Matrix Scientific 074465 (3-Amino-5-nitrophenyl)methanol 90390-46-8 5.00g $1519 2026-05-18 Buy
Product number Packaging Price Buy
AS32513 1g $72 Buy
AS32513 5g $309 Buy
074465 250.00mg $260 Buy
074465 1.00g $559 Buy
074465 5.00g $1519 Buy

(3-Amino-5-nitrophenyl)methanol Chemical Properties,Uses,Production

Synthesis

3,5-DINITROBENZYL ALCOHOL

71022-43-0

(3-AMINO-5-NITROPHENYL)METHANOL

90390-46-8

(ii) Synthesis of 3-amino-5-nitrobenzyl alcohol: 3,5-dinitrobenzyl alcohol (129.1 g, 0.65 mol) from step (i) was dissolved in methanol (1500 mL) and heated to reflux. Ammonium sulfide solution (450 mL, containing 20 wt% H2O, 442.9 g, 1.30 mol) was added slowly over 45 min. The resulting non-homogeneous mixture was refluxed for 2 hours, followed by stirring at 25 °C for 18 hours. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filtrate was acidified with 2N hydrochloric acid and the methanol was evaporated under reduced pressure. The remaining acidic aqueous solution was washed with ether (3×) and then alkalized with 6N sodium hydroxide solution. The alkalized aqueous solution was extracted with ether (4×). The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 95.8 g (88% yield) of 3-amino-5-nitrobenzenemethanol as an orange solid, which could be used in the next reaction without further purification. The product was characterized by 1H NMR (300 MHz, CD3OD): δ 7.46 (m, 1H), 7.38 (m, 1H), 6.98 (m, 1H), 4.57 (s, 2H).

References

[1] Tetrahedron Letters, 2003, vol. 44, # 29, p. 5477 - 5481
[2] Chinese Chemical Letters, 2011, vol. 22, # 7, p. 785 - 788
[3] Journal of Medicinal Chemistry, 1984, vol. 27, # 9, p. 1111 - 1118
[4] Bioorganic and medicinal chemistry letters, 2002, vol. 12, # 22, p. 3263 - 3265
[5] Journal of Labelled Compounds and Radiopharmaceuticals, 2002, vol. 45, # 3, p. 257 - 268

(3-Amino-5-nitrophenyl)methanol Preparation Products And Raw materials

Raw materials

3,5-Dinitrobenzyl alcohol Ammonium sulfide

Preparation Products

3-Chloro-5-nitrobenzaldehyde 3-Chloro-5-fluorobenzaldehyde 3-iodo-5-nitroBenzenemethanol

(3-Amino-5-nitrophenyl)methanol Suppliers

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 85114309 18982182443 yangli@happysyn.com China 2283 55
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Shanghai Witofly Chemical Co.,Ltd sales@witofly.com China 2853 52
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Wuhan Chemwish Technology Co.， Ltd 027-67849912 sales@chemwish.com China 9144 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Sichuan BoYou Biotechnology Co., Ltd. 028-65791793 18140026355 568470422@qq.com China 9961 58
Wuxi AppTec 022-59987777 13552403979 jia_guoqiang@wuxiapptec.com China 22344 58
Supplier Advantage
Wuhan Chemwish Technology Co., Ltd 56
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 55
Shanghai Topbiochem Technology Co., Ltd 58
Shanghai T&W Pharmaceutical Co., Ltd. 58
Shanghai Witofly Chemical Co.,Ltd 52
Cool Pharm, Ltd 58
Wuhan Chemwish Technology Co.， Ltd 60
Amadis Chemical Company Limited 58
Sichuan BoYou Biotechnology Co., Ltd. 58
Wuxi AppTec 58

(3-Amino-5-nitrophenyl)methanol Spectrum

(3-AMINO-5-NITROPHENYL)METHANOL(90390-46-8)1HNMR

90390-46-8((3-Amino-5-nitrophenyl)methanol)Related Search:

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Methyl 3,5-dinitrobenzoate 4-Chloro-3,5-dinitrobenzoic acid 3-Amino-5-nitrobenzoic acid Methyl 3,5-dinitrosalicylate 3,5-Dinitrobenzoic acid
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3-(Hydroxymethyl)-5-nitroaniline 3-Amino-5-nitrobenzenemethanol (3-AMINO-5-NITROPHENYL)METHANO Benzenemethanol, 3-amino-5-nitro- (3-Amino-5-nitrophenyl)methanol 90390-46-8