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2-Methylthiophene

2-Methylthiophene structure

CAS No.: 554-14-3

Chemical Name:: 2-Methylthiophene

Synonyms: Thiophene, 2-methyl-;methylthiol;2-Methylthiophene CAS NO.554-14-3;2-methylthiacyclopentadiene (2-methylthiophene);2MT;2-thiotolene;α-Thiotolene;2-methyl-thiophen;2-METHYLTHIOPHENE;5-Methylthiophene

CBNumber:: CB2386865

Molecular Formula:: C5H6S

Molecular Weight:: 98.17

MDL Number:: MFCD00005451

MOL File:: 554-14-3.mol

MSDS File:: SDS

Last updated:2026-01-13 11:17:25

Product description	Number	Pack Size	Price
2-Methylthiophene analytical standard	78833	1ml	$75.1
2-Methylthiophene >97.0%(GC)	M0635	25mL	$80
2-Methylthiophene >97.0%(GC)	M0635	500mL	$961
2-Methylthiophene 98%	M84208	25g	$46.1
2-Methylthiophene 98%	M84208	100g	$120.65
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2-Methylthiophene Properties

Melting point	-63 °C (lit.)
Boiling point	113 °C (lit.)
Density	1.014 g/mL at 25 °C (lit.)
vapor pressure	47.6 mm Hg ( 37.7 °C)
refractive index	n20/D 1.52(lit.)
Flash point	45 °F
storage temp.	2-8°C
solubility	immiscible
form	Liquid
color	Clear colorless to yellow
Specific Gravity	1.025 (20℃)
Odor	at 0.01 % in propylene glycol. sulfurous alliaceous onion roasted green
Odor Type	sulfurous
Water Solubility	immiscible
BRN	103734
InChI	1S/C5H6S/c1-5-3-2-4-6-5/h2-4H,1H3
InChIKey	XQQBUAPQHNYYRS-UHFFFAOYSA-N
SMILES	Cc1cccs1
LogP	2.330
CAS DataBase Reference	554-14-3(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	7115JAP77A
NIST Chemistry Reference	Thiophene, 2-methyl-(554-14-3)
EPA Substance Registry System	Thiophene, 2-methyl- (554-14-3)
UNSPSC Code	85151701
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02

Signal word

Danger

Hazard statements

H225

Precautionary statements

P210-P370+P378-P403+P235

PPE

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

F,Xn,Xi

Risk Statements

11-22-36/37/38-37-2017/11/22

Safety Statements

16-37/39-26-36-33-7/9

RIDADR

UN 1993 3/PG 2

WGK Germany

RTECS

XM9625000

10-13

TSCA

TSCA listed

HazardClass

PackingGroup

HS Code

29349990

Storage Class

3 - Flammable liquids

Hazard Classifications

Flam. Liq. 2

Limited Quantities

1.0 L (0.3 gallon) (liquid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

NFPA 704

	3
2		1

2-Methylthiophene price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	78833	2-Methylthiophene analytical standard	554-14-3	1ml	$75.1	2022-05-15	Buy
TCI Chemical	M0635	2-Methylthiophene >97.0%(GC)	554-14-3	25mL	$80	2025-07-31	Buy
TCI Chemical	M0635	2-Methylthiophene >97.0%(GC)	554-14-3	500mL	$961	2025-07-31	Buy
Sigma-Aldrich	M84208	2-Methylthiophene 98%	554-14-3	25g	$46.1	2025-07-31	Buy
Sigma-Aldrich	M84208	2-Methylthiophene 98%	554-14-3	100g	$120.65	2025-07-31	Buy

Product number	Packaging	Price	Buy
78833	1ml	$75.1	Buy
M0635	25mL	$80	Buy
M0635	500mL	$961	Buy
M84208	25g	$46.1	Buy
M84208	100g	$120.65	Buy

2-Methylthiophene Chemical Properties,Uses,Production

Chemical Properties

clear colorless to slightly yellow liquid

Uses

2-Methylthiophene, is used as a flavoring agent that naturally occurs in grilled and roasted beef, papaya, cooked shrimp, whiskey, and in trace amounts in roasted chicken;

Definition

ChEBI: 2-methylthiophene is a member of the class of thiophenes that is thiophene in which the hydrogen atom at position 2 is substituted by a methyl group. It has a role as a flavouring agent and a Maillard reaction product. It is a member of thiophenes and a volatile organic compound. It is functionally related to a thiophene.

Production Methods

2-Methylthiophene is commercially produced to 98 wt% purity by VP cyclization.

Application

2-Methylthiophene is a feasible raw material for the production of several of the important 2-substituted thiophenes. It may be used to manufacture 2-chloromethylthiophene (2-thenyl chloride), but this and further syntheses must be completed in situ, because of its instability.

Synthesis Reference(s)

The Journal of Organic Chemistry, 14, p. 638, 1949 DOI: 10.1021/jo01156a016
Tetrahedron Letters, 22, p. 2443, 1981 DOI: 10.1016/S0040-4039(01)92928-4

2-Methylthiophene synthesis

Synthesis of 2-Methylthiophene from 2-Bromo-5-methylthiophene

2-Methylthiophene Preparation Products And Raw materials

Raw materials

Thiophene(SIV) (9CI) 2,3,5-TRIMETHYLTHIOPHENE 2-Ethyl-5-methylthiophene 2-N-BUTYLTHIOPHENE

Preparation Products

5-METHYLTHIOPHEN-2-YLMETHYLAMINE 5-Methylthiophene-2-boronic acid METHYL 4-METHYLTHIOPHENE-2-CARBOXYLATE 2-(Chloromethyl)thiophene 4-Methyl-2-thiophenecarboxylic acid

2-Bromo-5-methylthiophene 5-Methylthiophene-2-carboxaldehyde 4-Bromo-5-methyl-2-thiophenecarbaldehyde 2-METHYLTETRAHYDROTHIOPHENE 3,5-DIBROMO-2-METHYLTHIOPHENE

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2-Methylthiophene Suppliers

Global( 332)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20126	58
airuikechemical co., ltd.	+86-18353166132	sales02@airuikechemical.com	China	983	58
JINING XINHE CHEMICAL CO., LTD	+8615318402391	sales@xinhepharma.com	China	809	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21595	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29830	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2951	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
airuikechemical co., ltd.	58
JINING XINHE CHEMICAL CO., LTD	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Finer Chemical Co., Ltd	58
Xiamen AmoyChem Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from 2-Methylthiophene manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-01	2-Methylthiophene 554-14-3	US $0.00 / kg	1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-09-25	methylthiol 554-14-3	US $9.00-0.90 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2024-12-24	2-Methylthiophene 554-14-3	US $0.00-0.00 / Kg	1Kg	99.99%	20 tons	airuikechemical co., ltd.

2-Methylthiophene
554-14-3
US $0.00 / kg
99%
Shaanxi Dideu New Materials Co. Ltd

methylthiol
554-14-3
US $9.00-0.90 / KG
99%
Henan Fengda Chemical Co., Ltd

2-Methylthiophene
554-14-3
US $0.00-0.00 / Kg
99.99%
airuikechemical co., ltd.

2-Methylthiophene Spectrum

2-Methylthiophene(554-14-3)MS 2-Methylthiophene(554-14-3)¹HNMR 2-Methylthiophene(554-14-3)¹³CNMR 2-Methylthiophene(554-14-3)IR1 2-Methylthiophene(554-14-3)Raman

554-14-3(2-Methylthiophene)Related Search:

Cephalothin sodium Tetrahydrothiophene Thifensulfuron 2-Thiophenecarboxaldehyde Cyclopropyl 2-thienyl ketone

Ethyl 2-thiophenecarboxylate 2-Acetylthiophene 2-Thiopheneglyoxylic acid 2,2'-BITHIOPHENE 5-NITROTHIOPHENE-2-CARBOXALDEHYDE

3-Methyl-2-thiophenecarboxylic acid 2-Thiophenecarboxylic acid hydrazide 2-Formyl-5-methylthiophene 4-Bromothiophene-2-carboxaldehyde 2-Thiophenecarbonitrile

3-Methyl-2-thiophenecarboxaldehyde 2-Carboxy-5-methylthiophene 2-Acetyl-3-methylthiophene

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2-Methylthiophene CAS NO.554-14-3 2-methylthiacyclopentadiene (2-methylthiophene) 2-methyl-thiophen alpha-methylthiophene 2-METHYLTHIOPHENE 2MT 2-Methylthiophene,98% methylthiophene,2-methylthiophene Thiophene, 2-methyl- 2-thiotolene 2-METHYLTHIOPHENE GC 99+% 5-Methylthiophene α-Thiotolene 2-Methylthiophene, 98% 25GR 2-Methylthiophene@2000 μg/mL in Toluene 2-Methylthiophene> methylthiol 2-Methylthiophene USP/EP/BP 2-Methylthiophene 554-14-3 2-Methylthiophene?New 554-14-3 CH3C4H3S 554143 Building Blocks Heterocyclic Building Blocks Thiophenes Heterocycle-oher series Chemistry Building Blocks Heterocyclic Building Blocks Thiophene&Benzothiophene Heterocycles Thiophenes thiophene Flavor