3,4-Dimethylisoxazol-5-amine
- CAS No.
- 19947-75-2
- Chemical Name:
- 3,4-Dimethylisoxazol-5-amine
- Synonyms
- 5-AMINO-3,4-DIMETHYLISOXAZOLE;5-AMino-3;NSC 143787;4-diMethylisoxazole;5-Amino-3,4-dimethyL;3,4-DIMETHYLISOXAZOL-5-AMINE;3,4-Dimethyl-5-isoxazolamine;5-Amino-3,4-dimethylisooxazole;3,4-dimethylisoxazol-5-ylamine;5-Isoxazolamine, 3,4-dimethyl-
- CBNumber:
- CB2389240
- Molecular Formula:
- C5H8N2O
- Molecular Weight:
- 112.13
- MDL Number:
- MFCD00046081
- MOL File:
- 19947-75-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Amino-3,4-dimethylisoxazole >98.0%(GC)(T) | A3179 | 5g | $146 |
| 5-Amino-3,4-dimethylisoxazole >98.0%(GC)(T) | A3179 | 25g | $517 |
| 5-Amino-3,4-dimethylisoxazole ≥98%(GC) | 43071 | 5G | $71.81 |
| 5-Amino-3,4-dimethylisoxazole ≥98%(GC) | 43071 | 25G | $268.8 |
| 3,4-Dimethylisoxazol-5-amine | 081327 | 1.00g | $37 |
| Melting point | 118-122 °C(lit.) |
|---|---|
| Boiling point | 246.0±35.0 °C(Predicted) |
| Density | 1.118±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO, Methanol |
| pka | -0.24±0.50(Predicted) |
| form | Solid |
| color | White to Off-White |
| BRN | 108546 |
| InChI | InChI=1S/C5H8N2O/c1-3-4(2)7-8-5(3)6/h6H2,1-2H3 |
| InChIKey | PYNDWPFZDQONDV-UHFFFAOYSA-N |
| SMILES | O1C(N)=C(C)C(C)=N1 |
| CAS DataBase Reference | 19947-75-2(CAS DataBase Reference) |
| FDA UNII | EX4SJ7E95P |
| NIST Chemistry Reference | 5-Amino-3,4-dimethyl-isoxazole(19947-75-2) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2934999090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
3,4-Dimethylisoxazol-5-amine price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A3179 | 5-Amino-3,4-dimethylisoxazole >98.0%(GC)(T) | 19947-75-2 | 5g | $146 | 2026-04-30 | Buy |
| TCI Chemical | A3179 | 5-Amino-3,4-dimethylisoxazole >98.0%(GC)(T) | 19947-75-2 | 25g | $517 | 2026-04-30 | Buy |
| Chem-Impex | 43071 | 5-Amino-3,4-dimethylisoxazole ≥98%(GC) | 19947-75-2 | 5G | $71.81 | 2026-05-19 | Buy |
| Chem-Impex | 43071 | 5-Amino-3,4-dimethylisoxazole ≥98%(GC) | 19947-75-2 | 25G | $268.8 | 2026-05-19 | Buy |
| Matrix Scientific | 081327 | 3,4-Dimethylisoxazol-5-amine | 19947-75-2 | 1.00g | $37 | 2026-05-18 | Buy |
3,4-Dimethylisoxazol-5-amine Chemical Properties,Uses,Production
Chemical Properties
White to Off-White Cyrstalline Solid
Uses
5-amino-3,4-dimethylisoxazole formed complexes with cobalt(II) and copper(II). The kinetics of gas-phase thermal isomerization of 5-amino-3,4-dimethylisoxazole was studied.
General Description
5-amino-3,4-dimethylisoxazole formed complexes with cobalt(II) and copper(II). The kinetics of gas-phase thermal isomerization of 5-amino-3,4-dimethylisoxazole was studied.
Synthesis
4468-47-7
19947-75-2
General procedure for the synthesis of 3,4-dimethylisoxazol-5-amine using 2-methyl-3-oxobutanenitrile as starting material: 2-methyl-3-oxobutanenitrile (9.7 g, 0.1 mol), hydroxylamine hydrochloride (7 g, 0.1 mol), and water (20 mL) were mixed, followed by the slow dropwise addition of NaOH aqueous solution (4 g dissolved in 10 mL of water) at 40 °C. After the dropwise addition, the reaction mixture was heated to reflux for 3 hours. After completion of the reaction, it was cooled to room temperature and phase separation was carried out. After the organic layer was allowed to stand overnight, filtration afforded the white crystalline product 3,4-dimethylisoxazol-5-amine (3.66 g, yield 32.7%) with a melting point of 123-125 °C.
References
[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 15, p. 4661 - 4667
[2] Pharmaceutical bulletin, 1954, vol. 2, # 1, p. 62 - 64
[3] Yakugaku Zasshi, 1951, vol. 71, p. 1356,1358
[4] Chem.Abstr., 1952, p. 8036
3,4-Dimethylisoxazol-5-amine Preparation Products And Raw materials
3,4-Dimethylisoxazol-5-amine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9542 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49967 | 58 |
| Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 +8618018249389 | sales@anikare.com | China | 9969 | 58 |
View Lastest Price from 3,4-Dimethylisoxazol-5-amine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 3,4-Dimethylisoxazol-5-amine
19947-75-2
|
1KG | 98% | 150KG | Career Henan Chemical Co |
-
- 3,4-Dimethylisoxazol-5-amine
19947-75-2
- $0.00
- 98%
- Career Henan Chemical Co
