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Aminoacetaldehyde dimethyl acetal

Aminoacetaldehyde dimethyl acetal Structure
Aminoacetaldehyde dimethyl acetal structure
CAS No.
22483-09-6
Chemical Name:
Aminoacetaldehyde dimethyl acetal
Synonyms
AMINOACETALDEHYDE DIMETHYL ACETAL;2,2-Dimethoxyethanamine;AMINOACETOLDEHYDE DIMETHYL ACETOL;2,2-Dimethyethanamine;Aminoacetaldehyde dimethyl acetal ,98%;AMINOACETALDEHYDE DIMETHYL ACETAL (OR) 2,2- DIMETHOXYETHYLAMINE (ADMA);anjiahuanchun;DIMETHYLAMINOACETAL;Dimethoxyethylamine;Ammoniated methanol
CBNumber:
CB2394455
Molecular Formula:
C4H11NO2
Molecular Weight:
105.14
MDL Number:
MFCD00008135
MOL File:
22483-09-6.mol
MSDS File:
SDS
Last updated:2026-01-13 11:18:10
Product description Number Pack Size Price
Aminoacetaldehyde dimethyl acetal 99% 121967 25ml $66.5
Aminoacetaldehyde dimethyl acetal 99% 121967 100ml $167.2
Aminoacetaldehyde Dimethyl Acetal >98.0%(GC)(T) A0801 25mL $36
Aminoacetaldehyde Dimethyl Acetal >98.0%(GC)(T) A0801 250mL $275
Aminoacetaldehyde dimethyl acetal 99% 121967 500ml $683
More product size
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Aminoacetaldehyde dimethyl acetal Properties

Melting point -78°C
Boiling point 135-139 °C/95 mmHg (lit.)
Density 0.965 g/mL at 25 °C (lit.)
refractive index n20/D 1.417(lit.)
Flash point 128 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility soluble in Chloroform, Methanol
pka 6.95±0.10(Predicted)
form Liquid
color Clear colorless to pale yellow
Water Solubility miscible
BRN 741868
InChI 1S/C4H11NO2/c1-6-4(3-5)7-2/h4H,3,5H2,1-2H3
InChIKey QKWWDTYDYOFRJL-UHFFFAOYSA-N
SMILES COC(CN)OC
CAS DataBase Reference 22483-09-6(CAS DataBase Reference)
FDA UNII XF4JYB7VV5
NIST Chemistry Reference Aminoacetaldehyde dimethyl acetal(22483-09-6)
EPA Substance Registry System Ethanamine, 2,2-dimethoxy- (22483-09-6)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS05
Signal word  Danger
Hazard statements  H226-H314
Precautionary statements  P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C,F,Xi
Risk Statements  10-34-36/37/38
Safety Statements  26-36/37/39-45-16-36
RIDADR  UN 1993 3/PG 3
WGK Germany  2
Hazard Note  Flammable/Corrosive
TSCA  TSCA listed
HazardClass  3
PackingGroup  III
HS Code  29225000
Storage Class 3 - Flammable liquids
Hazard Classifications Flam. Liq. 3
Skin Corr. 1B
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
2
3 0

Aminoacetaldehyde dimethyl acetal price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 121967 Aminoacetaldehyde dimethyl acetal 99% 22483-09-6 25ml $66.5 2025-07-31 Buy
Sigma-Aldrich 121967 Aminoacetaldehyde dimethyl acetal 99% 22483-09-6 100ml $167.2 2025-07-31 Buy
TCI Chemical A0801 Aminoacetaldehyde Dimethyl Acetal >98.0%(GC)(T) 22483-09-6 25mL $36 2025-07-31 Buy
TCI Chemical A0801 Aminoacetaldehyde Dimethyl Acetal >98.0%(GC)(T) 22483-09-6 250mL $275 2025-07-31 Buy
Sigma-Aldrich 121967 Aminoacetaldehyde dimethyl acetal 99% 22483-09-6 500ml $683 2025-07-31 Buy
Product number Packaging Price Buy
121967 25ml $66.5 Buy
121967 100ml $167.2 Buy
A0801 25mL $36 Buy
A0801 250mL $275 Buy
121967 500ml $683 Buy

Aminoacetaldehyde dimethyl acetal Chemical Properties,Uses,Production

Description

Aminoacetaldehyde dimethyl acetal, also known as 2,2-dimethoxy-ethylamine, is a critical intermediate in the synthesis of ivabradine hydrochloride, proline analogs, praziquantel, and other raw materials. The existing process for producing aminoacetal dimethyl acetate uses vinyl acetate as the starting material, and the target product is synthesized through bromination, Gabriel synthesis, and hydrazinolysis.

Chemical Properties

clear colorless to pale yellow liquid

Uses

Amino acetaldehyde dimethyl was used in preparation of chitosan- dendrimer hybrids having various functional groups such as carboxyl, ester and poly(ethylene glycol). It was used in an synthesis of a bicyclic proline analog from L-ascorbic acid and in 3-component reaction catalyzed by MgClO4 leading to α-aminophosphonates.

General Description

Aminoacetaldehyde dimethyl acetal reacts with sulfone, followed by hydrolysis and reductive amination by adding desired piperazine derivative to yield piperazine derivatives of 2-furanyl[1,2,4]triazolo[1,5-a][1,3,5]triazine.

Synthesis

1) to disposable in container, add the ammonia soln that monochloroacetaldehyde dimethyl acetal and concentration are 10～40%, stir;
2) by step 1) in reaction solution stir, this reaction solution is warming up to 100～150 ℃;
3) by step 2) in reaction solution distill, reclaim ammoniacal liquor, until steam without obvious cut;
4) in step 3) in reaction solution in to add concentration be 20%～50% aqueous sodium hydroxide solution, regulate pH to 12～14;
5) by step 4) in solution carry out rectifying, collect colourless and light yellow transparent liquid, be target product aminoacetaldehyde dimethyl acetal.

Purification Methods

Dry the acetal over KOH pellets and distil it through a 30cm vacuum jacketed Vigreux column (p 11). [Lawson J Am Chem Soc 75 3398 1953, Erickson et al. J Am Chem Soc 77 6640 1955, Beilstein 4 IV 1918.]

Aminoacetaldehyde dimethyl acetal synthesis

97-97-2
22483-09-6
Synthesis of Aminoacetaldehyde dimethyl acetal from Chloroacetaldehyde dimethyl acetal

Aminoacetaldehyde dimethyl acetal Preparation Products And Raw materials

Raw materials

Preparation Products

ethyl 2-(3-bromo-2-oxopyrazin-1(2H)-yl)acetate 6-Bromoisoquinoline ethyl 2-(3,4-dihydro-2,3-dioxopyrazin-1(2H)-yl)acetate 6-(bromomethyl)isoquinoline 6-Methylisoquinoline
2-MERCAPTOIMIDAZOLE 8-METHYL-ISOQUINOLINE 2-Aminoimidazole 1-Methyl-1,3-dihydro-imidazol-2-one Glycine, N-(2,2-dimethoxyethyl)-, ethyl ester
2-(4-BROMO-PHENYL)-1H-IMIDAZOLE 7-Hydroxyisoquinoline 3-Fluorobenzyl alcohol 2,2-DIMETHOXY-N-(PHENYLMETHYLENE)-1-ETHANAMINE Methyl 3-(2,2-dimethoxyethylamino)propanoate
N-[(3-Bromophenyl)methylene]-2,2-dimethoxyethanamine 2-(3-FLUORO-PHENYL)-1H-IMIDAZOLE

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Aminoacetaldehyde dimethyl acetal Suppliers

Global( 597)Suppliers
Supplier Tel Email Country ProdList Advantage
Asia Chem I and E (Jiangsu) Co Ltd
+8615105181882 mera.z@nitrobenzenechemical.com China 144 58
Hangzhou Qiwei Pharmatech Co.,Ltd
13282840061 mw@qwpharmatech.com China 109 58
Hebei Yanxi Chemical Co., Ltd. 		+8618531123677 faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531151365 mina@chuanghaibio.com China 18126 58
Hangzhou ICH Biofarm Co., Ltd 		+86-0571-28186870; +undefined8613073685410 sales@ichemie.com China 1006 58
airuikechemical co., ltd. 		+86-18353166132 sales02@airuikechemical.com China 983 58
Apeloa production Co.,Limited 		+8619933239880 admin@apcl.com.cn China 861 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3692 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 13620 58
Supplier Advantage
Asia Chem I and E (Jiangsu) Co Ltd
58
Hangzhou Qiwei Pharmatech Co.,Ltd
58
Hebei Yanxi Chemical Co., Ltd. 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hangzhou ICH Biofarm Co., Ltd 		58
airuikechemical co., ltd. 		58
Apeloa production Co.,Limited 		58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58

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View Lastest Price from Aminoacetaldehyde dimethyl acetal manufacturers

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2,2-Dimethoxyethylamine pictures 2026-01-18 2,2-Dimethoxyethylamine
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2,2-Dimethoxyethylamine pictures 2026-01-17 2,2-Dimethoxyethylamine
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 US $0.00 / KG 1KG ≥99% 1000mt/year Jinan Finer Chemical Co., Ltd
Aminoacetaldehyde dimethyl acetal pictures 2026-01-16 Aminoacetaldehyde dimethyl acetal
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 US $39.10 / Kg/Drum 200Kg/Drum 99.00%HPLC 10tons/month Asia Chem I and E (Jiangsu) Co Ltd

Aminoacetaldehyde dimethyl acetal Spectrum

2,2-Dimethoxyethylamine(22483-09-6)MS2,2-Dimethoxyethylamine(22483-09-6)1HNMR2,2-Dimethoxyethylamine(22483-09-6)13CNMR2,2-Dimethoxyethylamine(22483-09-6)IR12,2-Dimethoxyethylamine(22483-09-6)Raman

22483-09-6(Aminoacetaldehyde dimethyl acetal)Related Search:

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2-METHOXYETHYLAMINE Bromoacetaldehyde diethyl acetal Bromoacetaldehyde dimethyl acetal Dimethyldimethoxysilane Dimethyl fumarate
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Acetal Triethylamine Dimethoxymethane

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AMINOACETOLDEHYDE DIMETHYL ACETOL 2,2-Dimetoxyethyl Amine 2,2-Dimethoxyethylamin Glycinal dimethyl acetal Aminoacetaldehyd Dimethy Acetal Aminoacetaldehyde dimethyl ace anjiahuanchun Aminoacetaldehyde dimethyl acetal ,98% Aminoacetaldehyde dimethyl acetal,99% Aminoacetaldehyde di AMino acetaldehyde diMethyll acetal AMinoacetaldehyde diMethyl acetal, 99% 100GR AMinoacetaldehyde diMethyl acetal, 99% 25GR AMINOACETALDEHYDE DIMETHYL ACETAL FOR SY 2,2-Dimethoxyethylamine, 2-Amino-1,1-dimethoxyethane AMinoacetaltwo Methanol AMinoacetaldehyde DiMethyl Acetal, 97+% AMino acetaldehyde condensation of Methanol 2,2-Dimethyethanamine 2,2-dimethoxy-ethanamin 2,2-Dimethoxyethanamine Acetaldehyde, amino-, dimethyl acetal Ethanamine, 2,2-dimethoxy- DIMETHYLAMINOACETAL 2-AMINOACETALDEHYDE DIMETHYLACETAL 1-AMINO-2,2-DIMETHOXYETHANE 2,2-DIMETHOXYETHYLAMINE AMINOACETALDEHYDE DIMETHYL ACETAL 2-Methoxy-N-[2-methoxyethyl]-1-ethaneamine 2-Aminoacetaldehyde dimethylacetal 98% 2,2-DIMETHYLETHANAMINE β,β-diethoxy-N,N-dimethylethylamine Aminoacetaldehyde Dimethyl Acetal > Dimethoxyethylamine 2,2-Dimethoxyethylamine ISO 9001：2015 REACH AMINOACETALDEHYDE DIMETHYL ACETAL (OR) 2,2- DIMETHOXYETHYLAMINE (ADMA) 2,2-DIMETHOXY ETHYLAMINE(ADMA) 2'2-Dimethoxyethylamine Ammoniated methanol 22483-09-6 22483-09-06 22483-09-5 22483-09-4 22843-09-6 H2NCH2CHOCH32 CH32NCH2CHOC2H52 NH2CH2CHOCH32 Aldehydes Acetals/Ketals/Ortho Esters Organic Building Blocks Oxygen Compounds Carbonyl Compounds C1 to C6 Building Blocks Pharmaceutical Intermediates 1 22483-09-6