18-Hydroxycorticosterone

CAS No.
Chemical Name:
18-Hydroxycorticosterone
Synonyms
18-Hydroxycorticosterone;4-PREGNEN-11-BETA, 18,21-TRIOL-3,20-DIONE
CBNumber:
CB2400525
Molecular Formula:
C21H30O5
Molecular Weight:
362.46
MDL Number:
MFCD00042685
MOL File:
Mol file
Last updated:2026-09-12 18:51:18

18-Hydroxycorticosterone Properties

FDA UNII 4U5T0O9SI3

18-Hydroxycorticosterone Chemical Properties, Uses, Production

Description

18-hydroxycorticosterone is a derivative of corticosterone that has a weak electrolyte action. 18-hydroxycorticosterone serves as an intermediate in the synthesis of aldosterone by the aldosterone synthase in the zona glomerulosa.

Synthesis

Human CYP11B2, which catalyzes the synthesis of 18-hydroxycorticosterone, is located on chromosome 8 (8q21-q22), and consists of nine exons. Human CYP11B2 mRNA has 2935 bp, which encodes a protein of 503 residues.

Uses

18-Hydroxycorticosterone is a derivative of Corticosterone. 18-Hydroxycorticosterone is used as an intermediate in the synthesis of Aldosterone (A514700).

18-Hydroxycorticosterone Preparation Products And Raw materials

Raw materials

Preparation Products

18-Hydroxycorticosterone Suppliers

Global Suppliers ( 5)
Supplier Tel Email Country ProdList Advantage
Interchim S.A. -- interchim@interchim.com France 6280 76
CHEMICAL LAND21 -- sales21@chemicalland21.com South Korea 6266 74
Beijing Hengye Zhongyuan Chemical Co., Ltd -- 13552281129@163.com China 6168 64
Advanced Technology & Industrial Co., Ltd. -- sales@advtechind.com China 6488 75
Steraloids Inc. -- sales@steraloids.com United States 2357 68

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4-PREGNEN-11-BETA, 18,21-TRIOL-3,20-DIONE 18-Hydroxycorticosterone