ChemicalBook >> CAS DataBase List >>2-Amino-5-bromo-3-methylpyridine

2-Amino-5-bromo-3-methylpyridine

2-Amino-5-bromo-3-methylpyridine structure

CAS No.: 3430-21-5

Chemical Name:: 2-Amino-5-bromo-3-methylpyridine

Synonyms: 5-BROMO-3-METHYLPYRIDIN-2-AMINE;5-BROMO-3-METHYL-PYRIDIN-2-YLAMINE;2-Amina-5-bromo;TIMTEC-BB SBB003694;2-Amino-5-bromo-3-methyl;2-AMINO-5-BROMO-3-PICOLINE;2-Amina-5-bromo-3-picoline;2-Amino-5-bromo-3-picoline,98%;5-Bromo-3-methyl-2-pyridinamine;2-AMINO-3-METHYL-5-BROMOPYRIDINE

CBNumber:: CB2409508

Molecular Formula:: C6H7BrN2

Molecular Weight:: 187.04

MDL Number:: MFCD00068232

MOL File:: 3430-21-5.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:45

Request For Quotation

2-Amino-5-bromo-3-methylpyridine Properties

Melting point	88-95 °C(lit.)
Boiling point	250.0±35.0 °C(Predicted)
Density	1.5672 (rough estimate)
refractive index	1.5500 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform, Methanol
form	Solid
pka	4.96±0.49(Predicted)
color	Yellow
Sensitive	Hygroscopic
BRN	386426
InChI	InChI=1S/C6H7BrN2/c1-4-2-5(7)3-9-6(4)8/h2-3H,1H3,(H2,8,9)
InChIKey	KBLGGRWUEVCNPY-UHFFFAOYSA-N
SMILES	C1(N)=NC=C(Br)C=C1C
CAS DataBase Reference	3430-21-5(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-36/37

WGK Germany

HazardClass

IRRITANT

HS Code

29333999

NFPA 704

	1
2		0

2-Amino-5-bromo-3-methylpyridine price More Price(47)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	525537	2-Amino-5-bromo-3-methylpyridine 97%	3430-21-5	5g	$115	2025-07-31	Buy
Sigma-Aldrich	525537	2-Amino-5-bromo-3-methylpyridine 97%	3430-21-5	1g	$49	2023-06-20	Buy
TCI Chemical	A2154	2-Amino-5-bromo-3-methylpyridine >98.0%(GC)(T)	3430-21-5	1g	$27	2025-07-31	Buy
TCI Chemical	A2154	2-Amino-5-bromo-3-methylpyridine >98.0%(GC)(T)	3430-21-5	5g	$74	2025-07-31	Buy
TRC	A601829	2-Amino-5-bromo-3-methylpyridine	3430-21-5	10g	$165	2021-12-16	Buy

Product number	Packaging	Price	Buy
525537	5g	$115	Buy
525537	1g	$49	Buy
A2154	1g	$27	Buy
A2154	5g	$74	Buy
A601829	10g	$165	Buy

2-Amino-5-bromo-3-methylpyridine Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

Uses

2-Amino-5-bromo-3-methylpyridine may be used to synthesize:

5-bromo-2-chloro-3-methylpyridine
2-azidopyridine 1-oxide
2-amino-5-bromo-3-methylpyridine 1-oxide
2,5-dibromo-3-methyl pyridine
ethyl-3,6-dibromo-8-methylimidazo[1,2-a]pyridine-2-carboxylate

General Description

2-Amino-5-bromo-3-methylpyridine can be prepared from 2-amino-3-methylpyridine, via bromination.

Synthesis

1603-40-3

3430-21-5

General procedure for the synthesis of 2-amino-3-methyl-5-bromopyridine from 2-amino-3-methylpyridine: Bromine (15.4 mL, 0.30 mol) was slowly added dropwise to an anhydrous dichloromethane (1000 mL) solution of 2-amino-3-methylpyridine (32.44 g, 0.30 mol) under stirring at 0-2 °C for 1 hour. The cooling bath was then removed and the yellow suspension was allowed to continue stirring at room temperature for 3 hours and 40 minutes. Upon completion of the reaction, the mixture was alkalized to pH 9 with 2N sodium hydroxide solution (145 mL) and subsequently treated with a mixture of saturated aqueous sodium bicarbonate (100 mL) and saturated aqueous sodium thiosulfate (10 mL). The organic layer was separated, washed with brine, dried over magnesium sulfate and concentrated to give the brown solid product 2-amino-3-methyl-5-bromopyridine (56.83 g, 102% yield), which could be used in the next reaction without further purification.

References

[1] Patent: WO2004/13139, 2004, A2. Location in patent: Page 25-26
[2] Tetrahedron Letters, 2009, vol. 50, # 9, p. 1007 - 1009
[3] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001, vol. 40, # 11, p. 1129 - 1131
[4] Patent: CN105348177, 2016, A. Location in patent: Paragraph 0012; 0016
[5] Journal of Medicinal Chemistry, 2012, vol. 55, # 4, p. 1682 - 1697

2-Amino-5-bromo-3-methylpyridine synthesis

Synthesis of 2-Amino-5-bromo-3-methylpyridine from 2-Amino-3-picoline

2-Amino-5-bromo-3-methylpyridine Preparation Products And Raw materials

Raw materials

Hydrogen peroxide Sodium sulfite 2-Amino-3-picoline Hydrogen bromide Ethyl acetate

Bromine Acetic acid Dichloromethane Sodium hydroxide 2-ACETAMIDO-3-PICOLINE

1of2

Preparation Products

5-BROMO-2-CARBOXY-3-METHYLPYRIDINE 6-BROMO-8-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 2,5-Dibromo-3-methylpyridine 5-broMo-N,3-diMethylpyridin-2-aMine C-(6-Methoxy-5-methyl-pyridin-3-yl)-methylamine

6-Bromo-8-methyl-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester DI-TERT-BUTYL [5-BROMO-3-METHYLPYRIDIN-2-YL]IMIDODICARBONATE

1of2

2-Amino-5-bromo-3-methylpyridine Suppliers

Global( 479)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20188	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29734	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Fluoropharm Co., Ltd.	+86-0571-85586753 +86-13336034509	sales@fluoropharm.com	China	1445	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Zjartschem	+86-571 87238903	jocelynpan@zjarts.com	CHINA	988	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
Fluoropharm Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Zjartschem	58
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58

View Lastest Price from 2-Amino-5-bromo-3-methylpyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-22	2-Amino-5-bromo-3-methylpyridine 3430-21-5	US $0.00 / gm	100gm	99%min	100kgs	Shanghai Yongzeng Technology Co.,Ltd
2025-07-25	2-Amino-5-bromo-3-methylpyridine 3430-21-5	US $0.00-0.00 / KG	1KG	99.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-06-27	2-Amino-5-bromo-3-methylpyridine 3430-21-5	US $0.00-0.00 / KG	1KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd

2-Amino-5-bromo-3-methylpyridine
3430-21-5
US $0.00 / gm
99%min
Shanghai Yongzeng Technology Co.,Ltd

2-Amino-5-bromo-3-methylpyridine
3430-21-5
US $0.00-0.00 / KG
99.0%
Shaanxi Dideu New Materials Co. Ltd

2-Amino-5-bromo-3-methylpyridine
3430-21-5
US $0.00-0.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

2-Amino-5-bromo-3-methylpyridine Spectrum

2-Amino-5-bromo-3-methylpyridine(3430-21-5)¹HNMR 2-Amino-5-bromo-3-methylpyridine(3430-21-5)IR

3430-21-5(2-Amino-5-bromo-3-methylpyridine)Related Search:

2-Amino-5-bromo-3-(hydroxymethyl)pyridine 6-Bromo-3,4-dihydro-1H-[1,8]naphthyridin-2-one Methyl 2-amino-5-bromonicotinate 5-BROMO-2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE 2-Amino-5-bromonicotinic acid

5-BROMO-1H-PYRROLO[2 , 3-B]PYRIDIN-2(3H)-ONE (2-AMINO-5-BROMOPYRIDIN-3-YL)METHANOL HYDROBROMIDE 2-AMINO-5-BROMO-3,4-DIMETHYLPYRIDINE 2-Amino-5-bromo-3-methylpyridine 2-Acetylamino-5-bromo-3-methylpyridine

5-AMINO-2-BROMO-3-METHYLPYRIDINE,5-AMINO-2-BROMO-3-PICOLINE (5-AMINO-2-BROMO-3-METHYLPYRIDINE) 2-Amino-3-bromo-5-methylpyridine 4-Bromo-2-methyl-3-pyridinamine 4-AMINO-5-BROMO-3-METHYLPYRIDINE 3-Amino-2-bromo-4-methylpyridine

5-Amino-2-bromo-4-methylpyridine 2-AMINO-3-BROMO-4-METHYLPYRIDINE 3-Amino-5-bromo-2-methylpyridine

1of4

2-AMINO-5-BROMO-3-METHYLPYRIDINE 2-AMINO-5-BROMO-3-PICOLINE 2-AMINO-3-METHYL-5-BROMOPYRIDINE 2-AMINO-5-BROMO-3-METHYLPYRIDINE 98% 5-Bromo-3-methyl-2-pyridinamine 2-Amino-5-bromo-3-methyl 2-Amina-5-bromo-3-picoline 2-AMINO-5-BROMO-3-PICOLINE (2-AMINO-5-BROMO-3-METHYLPYRIDINE) JR-8255, 2-Amino-5-bromo-3-methylpyridine, 97% 2-Amino-5-bromo-3-picoline,98% 5-Bromo-3-methylpyridin-2-amine ,98% 2-Amino-5-bromo-3-methylpyridine ,98% 2-PyridinaMine, 5-broMo-3-Methyl- TIMTEC-BB SBB003694 5-BROMO-3-METHYLPYRIDIN-2-AMINE 5-BROMO-3-METHYL-PYRIDIN-2-YLAMINE 6-aMino-3-broMo-5-Methylpyridine 2-Amino-5-bromo-3-picoline, 5-Bromo-3-methylpyridin-2-amine 2-AMino-5-broMo-3-Methylpyridine SynonyMs 5-BroMo-3-Methylpyridin-2-aMine 2-Amino-5-bromo-3-methylpyridine,97% 5-broMo-3-Methyl-2-aMinopyridine 2-Amina-5-bromo 2-Amino-5-bromo-3-methylpyridine > 2-Amino-5-bromo-3-methylpyridine ISO 9001：2015 REACH 5-Bromo-3-methyl-pyridine-2-ylamine "2-Amino-3-methyl-5-bromopyridine 13C4, 15N" 3-methyl-2-amino-5-bromo pyridine 3430-21-5 30-21-5 430-21-5 C6H7N2Br Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyridines Pyridines, Pyrimidines, Purines and Pteredines Amines Pyridines Heterocyclic Compounds Chemical Amines Anilines, Amides & Amines Bromine Compounds Miscellaneous Compounds Bromopyridines Pyridine Amines and Anilines Heterocycles C6Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Halopyridines Bases & Related Reagents Heterocyclic Nucleotides Boronic Acid