3-CHLOROBENZHYDRAZIDE
- CAS No.
- 1673-47-8
- Chemical Name:
- 3-CHLOROBENZHYDRAZIDE
- Synonyms
- 3-chlorobenzohydrazide;RMA-106;ASISCHEM D51116;AKOS BBS-00004508;SPECS AN-068/40169986;3-CHLOROBENZHYDRAZIDE;3-Chlorobenzoylhydrazine;3-CHLOROBENZOIC HYDRAZIDE;3-Chlorobenzohydrazide >3-Chlorobenzhydrazide, 98+%
- CBNumber:
- CB2424392
- Molecular Formula:
- C7H7ClN2O
- Molecular Weight:
- 170.6
- MDL Number:
- MFCD00014757
- MOL File:
- 1673-47-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Chlorobenzohydrazide >98.0%(GC)(T) | C2648 | 5g | $33 |
| 3-Chlorobenzohydrazide >98.0%(GC)(T) | C2648 | 25g | $112 |
| 3-Chlorobenzoic hydrazide, min. 98% min.98% | 07-0128 | 25g | $30 |
| 3-Chlorobenzoic hydrazide, min. 98% min.98% | 07-0128 | 100g | $90 |
| 3-Chlorobenzohydrazide Asreported | 270581 | 5g | $317 |
| Melting point | 155-156°C |
|---|---|
| Density | 1.323±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | powder to crystal |
| pka | 11.86±0.10(Predicted) |
| color | White to Light yellow |
| BRN | 973243 |
| InChI | InChI=1S/C7H7ClN2O/c8-6-3-1-2-5(4-6)7(11)10-9/h1-4H,9H2,(H,10,11) |
| InChIKey | PHRDZSRVSVNQRN-UHFFFAOYSA-N |
| SMILES | C(NN)(=O)C1=CC=CC(Cl)=C1 |
| CAS DataBase Reference | 1673-47-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29280090 | |||||||||
| NFPA 704 |
|
3-CHLOROBENZHYDRAZIDE price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C2648 | 3-Chlorobenzohydrazide >98.0%(GC)(T) | 1673-47-8 | 5g | $33 | 2026-04-30 | Buy |
| TCI Chemical | C2648 | 3-Chlorobenzohydrazide >98.0%(GC)(T) | 1673-47-8 | 25g | $112 | 2026-04-30 | Buy |
| Strem Chemicals | 07-0128 | 3-Chlorobenzoic hydrazide, min. 98% min.98% | 1673-47-8 | 25g | $30 | 2026-04-30 | Buy |
| Strem Chemicals | 07-0128 | 3-Chlorobenzoic hydrazide, min. 98% min.98% | 1673-47-8 | 100g | $90 | 2026-04-30 | Buy |
| Usbiological | 270581 | 3-Chlorobenzohydrazide Asreported | 1673-47-8 | 5g | $317 | 2026-06-03 | Buy |
3-CHLOROBENZHYDRAZIDE Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder
Antimicrobial activity
3-Chlorobenzhydrazide is a dihedral molecule that can be classified as an antibacterial and antimycobacterial agent. The crystal x-ray diffraction study revealed that 3-chlorobenzhydrazide forms a hydrogen bond with hydroxyl groups of amino acids in proteins. This property makes it an effective antibacterial agent against Gram-positive bacteria such as staphylococci and Mycobacteria tuberculosis.
Synthesis
535-80-8
1673-47-8
General procedure for the synthesis of 3-chlorobenzhydrazide from 3-chlorobenzoic acid: a mixture of 3-chlorobenzoic acid (0.5 g, 3.19 mmol), 1,3-dicyclohexylcarbodiimide (0.72 g, 3.51 mmol), and 4-dimethylaminopyridine (0.04 g, 0.32 mmol) in ethanol was stirred for 1.5 h at room temperature. The white solid was collected by filtration and the filtrate was diluted with dichloromethane (100 mL). The organic phase was washed sequentially with 1N sodium bisulfate solution (100 mL), saturated sodium bicarbonate solution (100 mL), water (100 mL) and brine (100 mL). The organic layer was dried with anhydrous magnesium sulfate, filtered and the filtrate was concentrated under reduced pressure. The resulting crude product was dissolved in ethanol (15 mL) and hydrazine monohydrate (0.46 mL, 9.58 mmol) was added. The reaction mixture was stirred at room temperature overnight. Subsequently, the reaction mixture was concentrated to dryness under reduced pressure. The residue was purified by silica gel column chromatography with the eluent being a dichloromethane solution of 3% methanol to give 0.29 g (53% yield) of 3-chlorobenzohydrazide as a white solid.
References
[1] European Journal of Medicinal Chemistry, 2017, vol. 138, p. 396 - 406
[2] Patent: US2003/55085, 2003, A1
[3] Journal of Chemical Research, 2010, vol. 34, # 12, p. 680 - 683
[4] Journal of Chemical Research, 2011, vol. 35, # 4, p. 234 - 237
[5] Monatshefte fur Chemie, 2010, vol. 141, # 4, p. 479 - 484
3-CHLOROBENZHYDRAZIDE Preparation Products And Raw materials
3-CHLOROBENZHYDRAZIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2165 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Jinan Liheng Biotechnology Co., Ltd. | 15865262812 | info@lihengpharm.com | CHINA | 938 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
View Lastest Price from 3-CHLOROBENZHYDRAZIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 3-CHLOROBENZHYDRAZIDE
1673-47-8
|
$1.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 3-CHLOROBENZHYDRAZIDE
1673-47-8
- $1.00
- 99%
- Career Henan Chemical Co
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